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Measuring Health-Related Quality Of Life (HRQOL) During Inpatient Stroke Rehabilitation (S21.002)
CONCLUSIONS: EQ-5 ratings converged between stroke survivors and clinicians, suggesting it is valid and reliable to measure moderate stroke survivor HRQOL in inpatient rehabilitation. EQ-5 and FIM improvement were poorly associated; HRQOL may independently complement functional outcome assessment in inpatient rehabilitation. Future studies could explore different areas of function to clarify the factor structure of improvement on these measures relative to HRQL.Study Supported by: NIH, Kessler FoundationDisclosure: Dr. Frisina has received personal compensation for activities with Kessler Institute for Rehabilitation as an...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Frisina, P., Kutlik, A., Hreha, K., Barrett, A. Tags: Neuro-rehabilitation and Neural Repair Source Type: research

Ischemic stroke in a patient with Parry-Romberg syndrome (P4.064)
Conclusions:The only other reported patient with PRS and stroke was also found to have a PFO. It is possible that the elevated ANA seen in this patient correlates with propensity towards small venous clots not seen on ultrasound. This may lead to paradoxical emboli and ischemic strokes. It is important to note this potential association between PRS and ischemic stroke in young patients without other known risk factors. It would be worthwhile to treat this subset of patients with medications for secondary stroke prevention.Disclosure: Dr. Ebiana has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Khosa has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ebiana, V., Singh, S., Khosa, S., Moheb, N., Trikamji, B., Rao, N., Mishra, S. Tags: General Neurology: Vascular Neurology Source Type: research

What factors predict Fitbit adherence in Stroke and Parkinson disease? (P6.029)
Conclusions:The strongest predictor of adherence to daily activity monitoring was level of medical co-morbidity. Other determinants of adherence were self-efficacy for managing conditions, e-Health literacy and pain. Age and level of disability did not affect daily use of small wireless monitors to track activity in stroke and PD.Disclosure: Dr. Schrader has nothing to disclose. Dr. Mentis has nothing to disclose. Dr. Phipps has nothing to disclose. Dr. Barr has nothing to disclose. Dr. Gruber-Baldini has nothing to disclose. Dr. Yarbrough has nothing to disclose. Dr. Von Coelln has nothing to disclose. Dr. Shulman has rec...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Schrader, K., Mentis, H., Phipps, M., Barr, E., Gruber-Baldini, A., Yarbrough, K., Von Coelln, F. R., Shulman, L. Tags: Movement Disorders: Tics, Tremor & amp;amp; Ataxia II Source Type: research

Rate of Utilization and Determination of Withdrawal of Care among Acute Ischemic Stroke Patient Treated with Thrombolytics (P02.002)
CONCLUSIONS: Our results identify several individual and institution related factors that determine the use of "withdrawal of care" among thrombolytic treated ischemic stroke patients. The excessively high mortality and resource utilization mandates a more evidence based policy for "withdrawal of care" in these patients.Disclosure: Dr. Suri has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Gilani has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Suri, M. F., Adil, M., Gilani, W., Qureshi, A. Tags: P02 Ethics, Pain, and Palliative Care Source Type: research

Presence of decreased Intraepidermal Nerve Fiber Density consistent with Small Fiber Neuropathy in Patients with Central Post-Stroke Pain (P1.050)
CONCLUSIONS: We have demonstrated evidence of decreased ENFD in a small series of patients with CPSP. These findings do not imply causality; however, they do bring up several important questions for further consideration. Does the central nervous system injury associated with stroke result in small fiber neuropathy in certain patients? Are patients with asymptomatic, previously undiagnosed small fiber neuropathy at increased risk for developing CPSP following a stroke? Do these findings have any implication for treatment? Further studies including prospective analyses are necessary to better understand these findings for b...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Yushvayev-Cavalier, Y., Amory, C., Bernardini, G., Argoff, C. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research

Facial Colliculus and Opalski Stroke Syndromes Caused by Vertebral Artery Dissection. Case Report (P4.349)
Conclusion: Brainstem stroke syndromes are challenging to localize before brain imaging. In this case two embolic strokes happened. The first in the right facial colliculus causing the right 6th and 7th cranial nerves palsy. The second happened in the left lateral medulla extending below the pyramidal decussation causing a classical left lateral medullary syndrome with ipsilateral hemiparesis, which constitute a left Opalski stroke syndrome.Disclosure: Dr. Alghamdi has nothing to disclose. Dr. Ayoub has nothing to disclose. Dr. Alzahrani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alghamdi, S., Ayoub, O., Alzahrani, N. Tags: Cerebrovascular Case Reports Source Type: research

Palliative Care is Underutilized in Ischemic Stroke Patients with Poor Functional Outcome (P6.089)
Conclusions:Our observations suggest that PC may be underutilized in ischemic stroke patients, particularly in those who may benefit from it the most. PC has great potential to diminish suffering through physical and psychological symptom management. Providers should at least consider PC consults for hospitalized stroke patients.Disclosure: Dr. Gropen has nothing to disclose. Dr. Sisson has nothing to disclose. Dr. Albright has nothing to disclose. Dr. Lakkur has nothing to disclose. Dr. Bakitas has nothing to disclose. Dr. Sands has received research support from Biogen. Dr. Kaur has nothing to disclose. Dr. Lyerly has no...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gropen, T., Sisson, A., Albright, K., Lakkur, S., Bakitas, M., Sands, K., Kaur, M., Lyerly, M., Burgio, K. Tags: Pain and Palliative Care: Patient Safety and Quality Source Type: research

Parasylvian or Operculo-Insular Pain at the Onset of Stroke (P02.042)
CONCLUSIONS: As mentioned above, dysesthesia has been described in cases of parasylvian or operculo-insular infarcts during recovery from stroke, but we present a case where dysesthesia is the presenting symptoms itself. Recognizing such a possibility can help in guiding initial investigations.Supported by: Garcia-Larrea L, Perchet C, Creac'h C, et al. Operculo-insular pain (parasylvian pain): a distinct central pain syndrome. Brain 2010 Sep;133(9):2528-39.Disclosure: Dr. Kavi has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kavi, T. Tags: P02 Cerebrovascular Disease II Source Type: research

Cervical artery dissection: Trauma and other potential mechanical trigger events
Conclusion: PCT seems to be an important environmental determinant of CeAD, but was not an independent outcome predictor. Because of the characteristics of most PCTs, the term mechanical trigger event rather than trauma may be more appropriate.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Engelter, S. T., Grond-Ginsbach, C., Metso, T. M., Metso, A. J., Kloss, M., Debette, S., Leys, D., Grau, A., Dallongeville, J., Bodenant, M., Samson, Y., Caso, V., Pezzini, A., Bonati, L. H., Thijs, V., Gensicke, H., Martin, J. J., Bersano, A., Touze, E., Tags: Stroke in young adults, Other trauma, Carotid artery dissection ARTICLE Source Type: research

Increase in Rate of Utilization of Withdrawal of Care in Acute Ischemic Stroke in USA (P1.209)
Conclusions:We found a considerable increase in rate of withdrawal of care with aggressive treatment, which may be due to disease severity and/or patient/family preference. Prognostic models and clinical experience for severe stroke patients may be biased by frequent withdrawal of care, leading to errors in prognostication with significant consequences including premature withdrawal of care, suboptimal outcomes and higher risk of short-term mortalityStudy Supported by: NADisclosure: Dr. Adil has nothing to disclose. Dr. Zweifler has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Adil, M., Zweifler, R. Tags: Pain and Palliative Care Source Type: research

Recurrent Intra-Luminal Aortic Thrombus And Ischemic Stroke In A Patient With Essential Thrombocythemia (P6.262)
CONCLUSIONS: This case highlights the importance of recognizing essential thrombocythemia as an entity that can lead to devastating complications, including acute coronary syndrome and either arterial and venous thrombosis. Early recognition and effective cytoreductive therapy are cornerstones to the prevention of recurrent embolism. This case demonstrates that Intra-luminal thrombus may resolve and reappear, and can vary greatly in its clinical consequences.Disclosure: Dr. Vela-Duarte has nothing to disclose. Dr. Flaster has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Vela-Duarte, D., Flaster, M. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Mitochondrial Encephalopathy with Lactic Acidosis and Stroke (MELAS) presenting as an apparent neoplastic process (P5.015)
CONCLUSION: MELAS can mimic more common disorders. The slow onset of her symptoms and the MRI's appearance led to suspicion for neoplasm. This is the first report to our knowledge where MELAS has presented as such. Documentation of this and other unusual presentations of mitochondrial disease is crucial to appropriate diagnosis of the condition.Disclosure: Dr. Rothstein has nothing to disclose. Dr. Haq has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Rothstein, A., Haq, I. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology ePosters Source Type: research

Sustained Efficacy with IncobotulinumtoxinA in Upper-Limb Post-Stroke Spasticity Over 48 Weeks (a Phase 3, Placebo-Controlled Study with an Open-Label Extension) (P3.303)
Conclusions: For subjects with upper-limb spasticity after a stroke, repeated injections of incobotulinumtoxinA (400U each at 12-week intervals) showed sustained efficacy in reducing muscle tone and spasticity-associated disability, while confirming the favorable safety profile of incobotulinumtoxinA in this indication.Disclosure: Dr. Elovic has received personal compensation from Allergan, Inc., and Solstice Neurosciences. Dr. Brashear has received personal compensation for activities with Allergan, Ipsen, Revance and Concerta as a consultant. Dr. Brashear has received royalty payments from books royalties. Dr. Brashear h...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Elovic, E., Brashear, A., Munin, M., Kaňovsky, P., Hanschmann, A., Hiersemenzel, R., Marciniak, C. Tags: Neurorehabilitation Source Type: research

Avoidance of steroids in the reversible cerebral vasoconstriction syndrome
Reversible cerebral vasoconstriction syndrome (RCVS), characterized by multifocal constrictions of cerebral arteries resolving spontaneously within 3 months, most commonly presents with unusual, severe, mostly thunderclap headaches (severe pain peaking in less than 1 minute).1,2 Seizures and focal neurologic deficits related to cortical subarachnoid hemorrhage, intracerebral hemorrhage, ischemic stroke, or posterior reversible encephalopathy syndrome may occur.3–5 Treatment relies on rest; withdrawal of any vasoactive drugs; avoidance of triggering factors; administration of nimodipine, given by analogy to aneurysmal...
Source: Neurology - January 15, 2017 Category: Neurology Authors: Mawet, J. Tags: All Headache, Stroke in young adults, All Imaging, Vasculitis, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Central Post Stroke Pain: A Systematic Review (P4.219)
Conclusions:While CPSP has been linked to the thalamic region since the early 1900’s, the peer-reviewed literature showed equivocal results when examining location of stroke. Our systematic review suggests damage to the STP is associated with CPSP and this could provide insights into mechanisms and treatment. Moreover, historical connection of strokes in the thalamic region and CPSP should be reevaluated as many studies noted that strokes in other regions of the brain also produce CPSP.Study Supported by: N/ADisclosure: Dr. Singer has nothing to disclose. Dr. Conigliaro has nothing to disclose. Dr. Spina has nothing ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Singer, J., Conigliaro, A., Spina, E., Law, S., Levine, S. Tags: Neuro-rehabilitation: Mechanism of Recovery Source Type: research

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