Presence of decreased Intraepidermal Nerve Fiber Density consistent with Small Fiber Neuropathy in Patients with Central Post-Stroke Pain (P1.050)

CONCLUSIONS: We have demonstrated evidence of decreased ENFD in a small series of patients with CPSP. These findings do not imply causality; however, they do bring up several important questions for further consideration. Does the central nervous system injury associated with stroke result in small fiber neuropathy in certain patients? Are patients with asymptomatic, previously undiagnosed small fiber neuropathy at increased risk for developing CPSP following a stroke? Do these findings have any implication for treatment? Further studies including prospective analyses are necessary to better understand these findings for both diagnostic and treatment purposes. Study Supported by:Disclosure: Dr. Yushvayev-Cavalier has nothing to disclose. Dr. Amory has nothing to disclose. Dr. Bernardini has nothing to disclose. Dr. Argoff has received personal compensation for activities with Endo Pharmaceuticals, Eli Lilly, Janssen Pharmaceutica, Neurogesx, Horizon Pharma, Depomed, Eli Lilly, Covidien, Nuvo Research, Shionogi Pharmaceuticals, Pfizer, and Teva Neuroscience as a

Source: Neurology - April 8, 2015 Category: Neurology Authors: Yushvayev-Cavalier, Y., Amory, C., Bernardini, G., Argoff, C. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research