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Analysis of the clinical features and risk factors of kidney injury in patients with chronic heart failure-a retrospective cohort study
CONCLUSIONS: Kidney injury occurred in more than half of the patients with CHF during hospitalization. The independent risk factors for kidney injury in the CHF patients included sex (male), hypertension, and stroke. Kidney injury was positively correlated with age and serum potassium, and negatively correlated with serum albumin, hemoglobin concentration, LVEF, and ARB application.PMID:37559657 | PMC:PMC10407521 | DOI:10.21037/jtd-23-1016
Source: Journal of Thoracic Disease - August 10, 2023 Category: Respiratory Medicine Authors: Xiaoran Shen Hongliang Guo Guglielmo Mantica Hui Yuan Source Type: research

Epidemiological aspects of obstructive sleep apnea.
This article addresses OSA from an epidemiological perspective, from prevalence studies to economic aspects to co-morbidity. PMID: 26101650 [PubMed]
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Red blood cell distribution width and cardiovascular diseases.
CONCLUSIONS: Although the role of anisocytosis in the pathogenesis of cardiovascular diseases remains uncertain, the considerable evidence available so far suggests that the clinical use of RDW may be broadened beyond the conventional boundaries of erythrocyte disorders, in particular for assisting the diagnosis and prognostication of patients with ACS, ischemic cerebrovascular disease, PAD, HF and AF. PMID: 26623117 [PubMed - as supplied by publisher]
Source: Journal of Thoracic Disease - December 4, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Atrial fibrillation and sleep-disordered breathing.
Authors: Lavergne F, Morin L, Armitstead J, Benjafield A, Richards G, Woehrle H Abstract Atrial fibrillation (AF) is a common supraventricular arrhythmia that increases in prevalence with increasing age and in the presence of comorbidities such as heart failure (HF). AF increases the risk of a number of serious complications, including stroke and HF. As a result, the rate of hospitalization is high, making AF a costly disease. Treatment strategies for AF are broadly based around rate and rhythm control, either pharmacological or mechanical. There appear to be a number of links between sleep-disordered breathing (SD...
Source: Journal of Thoracic Disease - January 24, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Prevalence of carotid artery stenosis in Chinese patients with angina pectoris.
CONCLUSIONS: The prevalence of CAS was not rare in China when compared with that in western countries, and the presence of CAS was weakly correlated with the extent of CAD. Screening for CAS should be recommended in Chinese patients with CAD, especially in those with one or more CAS-associated risk factors. PMID: 26793351 [PubMed]
Source: Journal of Thoracic Disease - January 24, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The sympathetic nervous system and catecholamines metabolism in obstructive sleep apnoea.
Authors: Bisogni V, Pengo MF, Maiolino G, Rossi GP Abstract Obstructive sleep apnoea (OSA) is the most common sleep disorder of breathing in middle-aged and overweight subjects. It features recurrent episodes of upper airway total (apnoea) o partial (hypopnea) collapse during sleep, which are associated with a reduction in blood oxygen saturation and with arousal from sleep to re-establish airway patency. An association of OSA with dysregulation of the autonomous nervous system (ANS) and altered catecholamines (CAs) metabolism has been contended for years. However, the pathophysiology mechanisms underlying these al...
Source: Journal of Thoracic Disease - February 25, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Air particulate matter and cardiovascular disease: the epidemiological, biomedical and clinical evidence.
Authors: Du Y, Xu X, Chu M, Guo Y, Wang J Abstract Air pollution is now becoming an independent risk factor for cardiovascular morbidity and mortality. Numerous epidemiological, biomedical and clinical studies indicate that ambient particulate matter (PM) in air pollution is strongly associated with increased cardiovascular disease such as myocardial infarction (MI), cardiac arrhythmias, ischemic stroke, vascular dysfunction, hypertension and atherosclerosis. The molecular mechanisms for PM-caused cardiovascular disease include directly toxicity to cardiovascular system or indirectly injury by inducing systemic inf...
Source: Journal of Thoracic Disease - February 25, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Obstructive sleep apnoea and coronary artery disease.
Authors: Mandal S, Kent BD Abstract Obstructive sleep apnoea (OSA) is a highly prevalent disorder, which causes significant nocturnal and daytime symptoms, reduced quality of life, and impaired functional capacity. Importantly, however, OSA also appears to predispose to the development of a number of cardiovascular and metabolic diseases, including diabetes, hypertension, and stroke. In this review we explore its relationship with coronary artery disease (CAD), discussing mechanisms whereby it may promote the development of atherosclerosis, evidence of its effect on CAD incidence and outcomes, and coronary imaging ...
Source: Journal of Thoracic Disease - January 29, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Treating sleep disorders to improve blood pressure control and cardiovascular prevention: a dream come true?-a narrative review.
Authors: Maiolino G, Bisogni V, Silvani A, Pengo MF, Lombardi C, Parati G Abstract Hypertension is one of the primary risk factors for heart disease and stroke, the leading causes of death worldwide. Current evidence supports the treatment of high blood pressure (BP) values in order to obtain a substantial reduction of cardiovascular burden. Sleep plays an important role in maintaining nocturnal BP control and nocturnal hypertension which, in turn, can be affected by the presence of sleep disorders. Whilst respiratory disturbances have been extensively studied and their causal role in the development of nocturnal h...
Source: Journal of Thoracic Disease - November 22, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Relation of red cell distribution width with HAS-BLED score in patients with non-valvular atrial fibrillation
CONCLUSIONS: RDW value is associated with HAS-BLED value, and can be used as the independent predictive factor of high HAS-BLED scores.PMID:34164198 | PMC:PMC8182543 | DOI:10.21037/jtd-21-567
Source: Journal of Thoracic Disease - June 24, 2021 Category: Respiratory Medicine Authors: Hong-Li Cai Hao Chen Jing Wang Ling Xie Kou-Long Zheng Qing Zhang Source Type: research

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