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Elevated Blood Pressure Before Left Ventricular Assist Device Support Implant is Associated with an Increased Risk of Stroke
Despite the recent advances in Left Ventricular Assist Device (LVAD) therapy, stroke remains a frequent and catastrophic complication. Hypertension (HTN) after LVAD implant has been associated with an increased risk of stroke, but the association between HTN before LVAD implant and stroke has never been studied. We hypothesized that LVAD patients with elevated blood pressure (BP) during outpatient visits before the LVAD implant may have an increased risk of stroke.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: F. Castagna, S. Patel, S. Vukelic, S. Madan, O. Saeed, D. Sims, D. Goldstin, U.P. Jorde Tags: (978) Source Type: research

Systolic Blood Pressure on Discharge after Left Ventricular Assist Device Insertion is Associated with Subsequent Stroke
Stroke is a significant complication in patients supported with continuous-flow left ventricular assist devices (CF-LVAD) and hypertension (HTN) is a significant risk factor for stroke, but the association between blood pressure and stroke in LVAD patients is not well characterized.
Source: The Journal of Heart and Lung Transplantation - October 22, 2014 Category: Transplant Surgery Authors: Michael E. Nassif, Anjan Tibrewala, David S. Raymer, Adam Andruska, Eric Novak, Justin M. Vader, Akinobu Itoh, Scott C. Silvestry, Gregory A. Ewald, Shane J. LaRue Source Type: research

Stroke Volume Response to Exercise is Dependent on Disease Severity in Pulmonary Arterial Hypertension
This study aimed to describe changes in stroke volume (SV) during exercise in patients with pulmonary arterial hypertension (PAH) to allow for exercise-based risk stratification.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C. G öransson, N. Vejlstrup, J. Carlsen Source Type: research

RVOT-VTI/PASP Is a Novel Noninvasive Parameter of Pulmonary Artery Compliance and Improves After Treatment with Pulmonary Hypertension-Specific Therapy
Pulmonary artery compliance (PAC) is an independent predictor of mortality in patients with pulmonary hypertension (PH). We have previously shown that the ratio of echocardiography derived right ventricular outflow tract velocity time integral (RVOT-VTI; an estimate of stroke volume) to pulmonary artery systolic pressure (PASP) correlates with PAC measured by right heart catheterization. We sought to determine whether PH-specific therapy improves PAC in patients with pulmonary arterial hypertension (PAH).
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: M.S. Tanna, A. Fox, G.S. Troutman, P.T. Bhattacharya, J.N. Menachem, F. Mao, E.Y. Birati, P.R. Forfia, A. Vaidya, J.A. Mazurek Source Type: research

Cardiovascular Magnetic Resonance Imaging for Risk Assessment and Prediction of Clinical Worsening in Pulmonary Arterial Hypertension
To determine the clinically detectable changes of right ventricular (RV) volume and stroke volume (SV) that predicts clinical worsening in patients with pulmonary arterial hypertension (PAH).
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C. G öransson, N. Vejlstrup, J. Carlsen Source Type: research

Hypertension, Arterial Compliance and LVAD Pump Function
Hypertension (HTN) has been implicated as a risk factor for stroke in continuous-flow Left Ventricular Assist Device (LVAD) populations. Active treatment of HTN has been shown to decrease cerebrovascular accident rates in the recent trial. Current guidelines recommend a mean arterial pressure (MAP) of 80mmHg in LVAD patients; however, it is difficult to reliably measure Blood Pressure (BP) in this cohort. Increased BP will further affect pump output since LVAD flows are altered by both preload and afterload.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: A. Adji, S. Shehab, P. Jain, D. Robson, P. Jansz, C. Hayward Tags: (371) Source Type: research

Physiologically Significant Pulsatility Key to Reducing Adverse Events in CF LVADS
Hypertension is common in continuous flow LVAD (CFLVAD) patients and is linked to major adverse events like stroke and aortic incompetence.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: K. Balakrishnan, R. Krishnakumar Tags: (1037) Source Type: research

Prolonged Circulatory Arrest is Not Associated with Stroke or Mortality after Pulmonary Thromboendarterectomy
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) frequently present with extensive distal clot burden, which adds complexity to pulmonary thromboendarterectomy (PTE). Complete endarterectomy often necessitates prolonged periods of hypothermic circulatory arrest (HCA), the ramifications of which are poorly understood. Objectives were to describe the association of HCA time with post-operative neurologic complications, operative mortality and other major morbidity after PTE.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: J.L. Armstrong, A.M. Vekstein, A. Seas, C.M. Wojnarski, A.M. Ganapathi, J.C. Haney Tags: (433) Source Type: research

Reservoir Pressure Analysis in Group 2 Pulmonary Hypertension
In this study we aim to describe Pres in Group 2 isolated post-capillary (IPC) and combined pre and post-capillary (CPC) pulmonary hypertension (PH).
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: I. Yim, K. Parker, S. Lim Tags: (307) Source Type: research