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Source: Journal of the Neurological Sciences
Condition: Hypertension
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Total 43 results found since Jan 2013.
Cerebral microbleeds in a multiethnic elderly community: Demographic and clinical correlates
Conclusions: Microbleeds in deep and lobar locations are associated with worse outcomes than microbleeds in either location alone, although the presence of lobar microbleeds appears to be more clinically relevant.Highlights:
Source: Journal of the Neurological Sciences - July 21, 2014 Category: Neurology Authors: Anne F. Wiegman, Irene B. Meier, Nicole Schupf, Jennifer J. Manly, Vanessa A. Guzman, Atul Narkhede, Yaakov Stern, Sergi Martinez-Ramirez, Anand Viswanathan, José A. Luchsinger, Steven M. Greenberg, Richard Mayeux, Adam M. Brickman Tags: Original Articles Source Type: research
CNS-disease affecting the heart: Brain–heart disorders
Abstract: There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain–heart disorders). The most well-known of these CNS-disorders are epilepsy, stroke, subarachanoid bleeding, bacterial meningitis, and head injury. In addition, a number of hereditary and non-hereditary neurodegenerative disorders may impair cardiac functions. Affection of the heart may manifest as arrhythmias, cardiomyopathy, or autonomic dysfunction. Rarer cardiac complications of CNS disorders include heart failure, systolic or diastolic dysfunction, myocardial infarc...
Source: Journal of the Neurological Sciences - July 10, 2014 Category: Neurology Authors: Josef Finsterer, Karim Wahbi Tags: Reviews Source Type: research
Genetic variations of MMP9 gene and intracerebral hemorrhage susceptibility: A case–control study in Chinese Han population
Conclusions: The genetic variations of MMP9 gene were not significantly associated with ICH susceptibility in the Chinese Han population.Highlights:
Source: Journal of the Neurological Sciences - April 28, 2014 Category: Neurology Authors: Jie Yang, Bo Wu, Sen Lin, Junshan Zhou, Yingbin Li, Wei Dong, Hisatomi Arima, Chanfei Zhang, Yukai Liu, Ming Liu, for the Chengdu stroke registry and Nanjing First Hospital stroke registry investigators Tags: Original Articles Source Type: research
Clinico-radiological predictors of vascular cognitive impairment (VCI) in patients with stroke: A prospective observational study
Conclusion: Post-stroke cognitive impairment is frequent and is associated with poor functional outcome. Predictors like lower educational status, strategic site lesion, greater severity of age related white matter changes and baseline stroke severity independently contributed to the risk of developing VCI in stroke patients.Highlights:
Source: Journal of the Neurological Sciences - March 31, 2014 Category: Neurology Authors: Tejendra Sukdeo Chaudhari, Rajesh Verma, Ravindra Kumar Garg, Manish Kumar Singh, Hardeep Singh Malhotra, Praveen kumar Sharma Tags: Original Articles Source Type: research
Basilar artery bending length, vascular risk factors, and pontine infarction
In this study, pontine infarction patients were analyzed to assess the effect of BA bending length (BL) together with other vascular factors on pontine stroke risk.Methods: Acute pontine infarction patients were divided into BA bending and non-BA bending groups by magnetic resonance angiography (MRA). Patients with BA bending who reported symptoms of dizziness or vertigo but who had not suffered brain infarction constituted the control group. The diameter of the vertebral artery (VA) and BL were measured using MRA. Based on the bilateral VA diameter data in vertebral artery-dominant (VAD) patients, the study participants w...
Source: Journal of the Neurological Sciences - February 18, 2014 Category: Neurology Authors: Dao-pei Zhang, Shu-ling Zhang, Jie-wen Zhang, Hong-tao Zhang, Sheng-qi Fu, Meng Yu, Ya-fang Ren, Peng Ji Tags: Original Articles Source Type: research
Risk factors and acute ischemic stroke subtypes
Conclusion: Specific AIS etiology and blood characteristics associated independently to the youngest and oldest AIS patients, respectively. Chronic kidney disease was a specific predictor of cerebellum–brainstem AIS. AIS mortality showed peculiar association with the oldest patients.
Source: Journal of the Neurological Sciences - January 31, 2014 Category: Neurology Authors: Aliaksei Kisialiou, Rodolfo Grella, Albino Carrizzo, Giordana Pelone, Michelangelo Bartolo, Chiara Zucchella, Francesco Rozza, Giovanni Grillea, Claudio Colonnese, Luigi Formisano, Maria Lembo, Annibale A. Puca, Carmine Vecchione Tags: Original Articles Source Type: research
Risk factors and etiological subtype analysis of brainstem infarctions
Abstract: Objective: To evaluate the features of risk factors and etiological subtypes of brainstem infarctions (BSIs) patients in China.Methods: One hundred and ninety-nine cerebral infarction patients with brainstem involvement were categorized into five groups according to Trial of Org 10172 in Acute Stroke Treatment classification: large artery disease (LAD), cardioembolism (CE), small vessel disease (SVD), stroke of other determined etiology (SOE) or stroke of undetermined etiology (SUE). The risk factors and percentage of the different etiological subtypes were assessed.Result: A total of 199 patients were enrolled i...
Source: Journal of the Neurological Sciences - January 10, 2014 Category: Neurology Authors: Yinyao Lin, Lei Zhang, Jian Bao, Bingjun Zhang, Haiyan Li, Suqin Chen, Shaoyang Sun, Xuejiao Men, Zhengqi Lu Tags: Original Articles Source Type: research
Stroke-prone renovascular hypertensive rat as an animal model for stroke studies: From artery to brain
Abstract: High blood pressure is a main risk factor for both initial and recurrent stroke. Compared to the poststroke situation in normotension, the brain lesion is larger in hypertension, and the treatments may not be as effective. Thus, the results from healthy individuals may not be directly applied to the hypertensive. In fact, the high prevalence of hypertension in stroke patients and its devastating effect urge the necessity to integrate arterial hypertension in the study of stroke in order to better mimic the clinical situations. The first step to do so is to have an appropriate hypertensive animal model for stroke ...
Source: Journal of the Neurological Sciences - August 19, 2013 Category: Neurology Authors: Song-Jie Liao, Ru-Xun Huang, Zhen-Pei Su, Jin-Sheng Zeng, Jian-Wei Mo, Zhong Pei, Ling Li, Yan-Nan Fang, Hua Hong, Hai-Wei Huang Tags: Review Source Type: research
Stroke warning syndrome: 18 new cases
Conclusion: SWS is an under-recognized syndrome. Intravenous rt-PA treatment seems to have lower efficacy than in other subtypes of strokes, but none of the patients with SWS undergoing treatment presented haemorrhagic transformation or other complications.
Source: Journal of the Neurological Sciences - June 13, 2013 Category: Neurology Authors: Rossana Tassi, Alfonso Cerase, Maurizio Acampa, Paolo D’Andrea, Francesca Guideri, Giuseppe Lo Giudice, Giovanna Marotta, Sandra Bracco, Giuseppe Martini Tags: Short Communictions Source Type: research
Association of ALOX5AP1 SG13S114T/A variant with ischemic stroke, stroke subtypes and aspirin resistance
Abstract: The important role of genetic variants in the etiology and pathophysiology of stroke is being increasingly recognized. Simultaneously, the influence of genetic factors in the clinical outcome of drug therapy cannot be ignored. 5-lipoxygenase activating (ALOX5AP) gene involved in the synthesis of leukotrienes, has been recognized as an important gene contributing towards susceptibility of stroke risk. Leukotrienes are involved in the physiological mechanism of atherosclerotic events and inflammation. The present study was designed to identify the association of SG13S114T/A polymorphism in ALOX5AP1 gene with risk o...
Source: Journal of the Neurological Sciences - June 10, 2013 Category: Neurology Authors: Vandana Sharma, Sneha Dadheech, Subhash Kaul, A. Jyothy, Anjana Munshi Tags: Original Articles Source Type: research
CHADS2 score predicts functional outcome of stroke in patients with a history of coronary artery disease
Abstract: Background: The aim of this study was to evaluate the efficacy of the CHADS2 scoring system as a prognostic tool for stroke patients with a prior history of coronary artery disease (CAD).Methods: We enrolled 148 acute ischemic stroke patients (mean age, 74.2years; males, 77.0%) with a history of CAD. Pre-admission CHADS2 scores were calculated by assigning a single point for the presence of congestive heart failure, hypertension, age ≥75years, and diabetes; and assigning 2 points for a prior history of stroke or transient ischemic attack. Comparisons were made between patients with poor and good 3-month functio...
Source: Journal of the Neurological Sciences - May 28, 2013 Category: Neurology Authors: Takao Hoshino, Kentaro Ishizuka, Satoru Shimizu, Shinichiro Uchiyama Tags: Original Articles Source Type: research
Cerebral hemorrhages in CADASIL: Report of four cases and a brief review
Conclusions: Hemorrhagic stroke can occur in CADASIL similarly to sporadic cerebral small vessel diseases; this finding expands the phenotype of the disease. A diagnosis of CADASIL should probably be considered also in patients with ICH. These data bear potential implications in terms of need of better control of risk factors, particularly hypertension, and raise relevant questions about the use of antiplatelets as prevention measures in CADASIL patients.
Source: Journal of the Neurological Sciences - May 2, 2013 Category: Neurology Authors: Valentina Rinnoci, Serena Nannucci, Raffaella Valenti, Ida Donnini, Silvia Bianchi, Francesca Pescini, Maria Teresa Dotti, Antonio Federico, Domenico Inzitari, Leonardo Pantoni Tags: Original Articles Source Type: research
Risk factors for stroke among patients with hypertension: A case–control study
Abstract: Background: In some African countries, more than half of the adult population are estimated to be hypertensive leading to an escalated burden of stroke in the continent. We conducted the first study to unravel the major risk factors for stroke among hypertensive patients (Nigerian-Africans) using a case–control design while also exploring the relative contributions of carotid intima medial thickness (CIMT) and carotid diameter as risk markers for stroke.Methods: Using conventional techniques, stroke-related demographic, clinical and laboratory data were obtained from 135 consecutive volunteering hypertensive st...
Source: Journal of the Neurological Sciences - December 20, 2012 Category: Neurology Authors: M.O. Owolabi, A.M. Agunloye Tags: Original Articles Source Type: research
