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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hypertension
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Total 220 results found since Jan 2013.
Infarction in the Anterior Choroidal Artery Territory: Clinical Progression and Prognosis Factors
This study was undertaken to describe the still poorly known evolving profile of anterior choroidal artery (AChA) infarctions, identify their prognosis factors, and evaluate responses to intravenous (IV) thrombolysis. During 42 months, we prospectively enrolled patients with an isolated AChA stroke. Clinical and radiologic parameters were compared between patients with or without progression, defined as any clinical worsening. Factors associated with poor outcome (dependence or death) were tested, and IV thrombolysis responses were assessed. For the 100 of 1234 (8.1%) analyzed patients with AChA stroke (predominantly lacu...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Nicolas Chausson, Julien Joux, Martine Saint-Vil, Mireille Edimonana, Séverine Jeannin, Mathieu Aveillan, Philippe Cabre, Stéphane Olindo, Didier Smadja Tags: Original Articles Source Type: research
Clinical Characteristics of Cardioembolic Transient Ischemic Attack: Comparison with Noncardioembolic Transient Ischemic Attack
Conclusions: Clinical features are similar in tissue-defined TIA of cardioembolic and noncardioembolic etiologies. The CHADS2 score can be useful in assessing the probability of cardioembolic TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Takeshi Hayashi, Yoshihide Seahara, Yuji Kato, Takuya Fukuoka, Ichiro Deguchi, Yasuko Ohe, Hajime Maruyama, Yohsuke Horiuchi, Hiroyasu Sano, Yuito Nagamine, Norio Tanahashi Tags: Original Articles Source Type: research
Frequency and Determinants of Intracranial Atherosclerotic Stroke in Urban Pakistan
Conclusions: ICAD accounted for one fifth of all strokes making it the most common ischemic stroke mechanism. In addition to aggressive risk factor control, data also indicated broader holistic efforts on ameliorating inequity, unemployment, and stress reduction to reduce stroke because of ICAD.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Ayeesha K. Kamal, Asif Rasheed, Khalid Mehmood, Muhammad Murtaza, Moazzam Zaidi, Maria Khan, Nabi Shah, Maria Samuel, Bilal Ahmed, Emmon Raza, Naveeduddin Ahmed, Jamal Ara, Tasnim Ahsan, Syed M. Munir, Shoukat Ali, Karim U. Maki, Muhammad M. Ahmed, Abdul Tags: Original Articles Source Type: research
Long-term Prognosis of Patients Presenting First-ever Vestibular Symptoms in a Community-based Study
Conclusions: First-ever-in-lifetime VSs are common in patients with FNS and may represent a good opportunity for preventing a serious vascular event, particularly in patients with vascular comorbidity (silent infarctions and VRFs).
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2014 Category: Neurology Authors: Rui Felgueiras, Rui Magalhães, Manuel Correia, Maria Carolina Silva Tags: Original Articles Source Type: research
Safety of Standard-dose (.9-mg/kg) Alteplase Intravenous Thrombolysis for Acute Ischemic Stroke in Afro–Caribbeans, French West Indies
Conclusions: The excess hemorrhagic risk after standard-dose alteplase infusion into older Afro–Caribbean patients warrants further study to determine the possible role of cerebral microangiopathy and should be evaluated in different black populations.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Nicolas Chausson, Stéphane Olindo, Julien Joux, Martine Saint-Vil, Mathieu Aveillan, Didier Smadja Tags: Original Articles Source Type: research
Prevalence of Ischemic and Hemorrhagic Strokes in Qena Governorate, Egypt: Community-based Study
Conclusions: The overall prevalence rate of stroke is nearly the same as in other Egyptian governorates and is higher than other Arabic countries.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Eman M. Khedr, Gharib Fawi, Mohamed Abdela, Talal A. Mohammed, Mohamed A. Ahmed, Noha Abo El-Fetoh, Ahmed F. Zaki Tags: Original Articles Source Type: research
Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African Americans with Ischemic Stroke
Conclusions: Prevalence of LVSD in AA with IS was 22% in our study. Smoking was a significant modifiable RF associated with systolic dysfunction. A history of smoking and higher age could predict the occurrence of LVSD. There were more large-vessel IS in patients with LVSD.
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2014 Category: Neurology Authors: Saravana Devulapalli, Shariff Dunlap, Nakia Wilson, Stephen Cockburn, Mohankumar Kurukumbi, Prafulla Mehrotra, Annapurni Jayam-Trouth Tags: Original Articles Source Type: research
Telmisartan Reduces Progressive Oxidative Stress and Phosphorylated α-Synuclein Accumulation in Stroke-resistant Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion
We examined the effects of telmisartan on oxidative stress by advanced glycation end product (AGE) and 4-hydroxynonenal (4-HNE) assays and the accumulation of phosphorylated α-synuclein (pSyn) in the brain of stroke-resistant spontaneously hypertensive rats (SHR-SR). At the age of 12 weeks, SHR-SR received transient middle cerebral artery occlusion (tMCAO) for 90 minutes and were divided into the following 3 groups: the vehicle group, the low-dose telmisartan group (.3 mg/kg/day), and the high-dose telmisartan group (3 mg/kg/day, postoperatively). Immunohistologic analysis was performed when rats were 6, 12, and 18 m...
Source: Journal of Stroke and Cerebrovascular Diseases - April 28, 2014 Category: Neurology Authors: Kota Sato, Toru Yamashita, Tomoko Kurata, Violeta Lukic, Yusuke Fukui, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research
Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion
Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality–associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2014 Category: Neurology Authors: Sibel Güler, Ufuk Utku, Özer Aynaci Tags: Original Articles Source Type: research
Occurrence and Predictors of Persistent Impaired Glucose Tolerance After Acute Ischemic Stroke or Transient Ischemic Attack
Conclusions: Half of the patients with impaired glucose tolerance after a TIA or ischemic stroke have persistent impaired glucose tolerance. We provide a prediction model to identify patients at risk of persistent impaired glucose tolerance, with statin use, triglyceride, and fasting plasma glucose as the most important predictors, which after external validation might be used to optimize secondary prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2014 Category: Neurology Authors: Susanne Fonville, Heleen M. den Hertog, Adrienne A.M. Zandbergen, Peter J. Koudstaal, Hester F. Lingsma Tags: Original Articles Source Type: research
Ischemic Strokes in Pakistan: Observations from the National Acute Ischemic Stroke Database
Conclusions: Hypertension and dyslipidemia were the most common risk factors and large vessel atherosclerosis was the most common stroke etiology. Elderly patients were significantly more likely to have in-hospital complications, die during their hospital stay, and have a higher mRS score at discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2014 Category: Neurology Authors: Bhojo A. Khealani, Maria Khan, Muhammad Tariq, Abdul Malik, Alam I. Siddiqi, Safia Awan, Mohammad Wasay Tags: Original Articles Source Type: research
High Blood Pressure on Admission in Relation to Poor Outcome in Acute Ischemic Stroke with Intracranial Atherosclerotic Stenosis or Occlusion
Conclusions: Higher BP on admission was associated with an increased risk of death or disability in patients with symptomatic intracranial artery stenosis or occlusion. It is reasonable that further studies on the effects of BP lowering in acute stroke include these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Zilong Hao, Ming Liu, Deren Wang, Bo Wu, Wendan Tao, Xueli Chang Tags: Original Articles Source Type: research
Protective Effect of Telmisartan Against Progressive Oxidative Brain Damage and Synuclein Phosphorylation in Stroke-resistant Spontaneously Hypertensive Rats
Previously, we reported that reactive oxygen species and signaling molecules of angiotensin II produced lipid peroxides, degenerated proteins, and injured DNA after cerebral ischemia in normotensive Wistar rats. Here, we investigated the long-term effect of the angiotensin II type I receptor blocker telmisartan on oxidative stress and hyperphosphorylated α-synuclein accumulation in stroke-resistant spontaneously hypertensive rats (SHR-SR). At the age of 3 months, SHR-SR were divided into 3 treatment groups: SHR-SR vehicle (SHR/Ve), SHR-SR low-dose telmisartan (.3 mg/kg/day) (SHR/low), and SHR-SR high-dose telmisartan (3...
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Yusuke Fukui, Toru Yamashita, Tomoko Kurata, Kota Sato, Violeta Lukic, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research
High Blood Pressure on Admission in Relation to Poor Outcome in Acute Ischemic Stroke with Intracranial Atherosclerotic Stenosis or Occlusion
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2014 Category: Neurology Authors: Zilong Hao, Ming Liu, Deren Wang, Bo Wu, Wendan Tao, Xueli Chang Tags: Original Articles Source Type: research
Association of rs2075575 and rs9951307 Polymorphisms of AQP-4 Gene with Leukoaraiosis
Background: Leukoaraiosis (LA) is associated with structural and functional vascular changes that correlate with motor and gait disturbances, depressive symptoms, urinary disturbances, and dementia. The blood–brain barrier (BBB) plays a key role in development of lacunar stroke, leukoaraiosis, and other feature of cerebral small-vessel disease, and there are numerous studies examining changes in the BBB with normal aging and in dementia and LA. Aquaporin-4 (AQP-4), the primary water channel protein in the central nervous system, is involved in BBB development, function, and integrity, and its dysfunction induces several ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2014 Category: Neurology Authors: Binod K. Yadav, Sun-Young Oh, Nam-Keun Kim, Byoung-Soo Shin Tags: Original Articles Source Type: research
