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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hypertension
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Total 220 results found since Jan 2013.
A Puzzling Case of Cryptogenic Stroke
Background: Stroke is a common neurological complication of infective endocarditis (IE) and it is associated with increased morbidity and mortality but infective endocarditis in acute stroke setting is hard to discover. Material and methods: A 75-year-old man referred to hospital for the onset of left hemiparesis and dysarthria. His past medical history included hypertension. He had 3 months history of fatigue, fever, and weight loss. Neurological examination revealed left hemiparesis and dysarthria.
Source: Journal of Stroke and Cerebrovascular Diseases - January 17, 2019 Category: Neurology Authors: Marisa Distefano, Rosalinda Calandrelli, Vincenzo Arena, Alessandro Pedicelli, Giacomo Della Marca, Fabio Pilato Tags: Case Report Source Type: research
A Unique Recurrent Stroke Case due to Bilateral Vertebral Artery Dissection with Familial Hirschsprung Disease
Vertebral artery (VA) dissection is one major cause of brain infarction in young and middle-aged adults. Risk factors for VA dissection are hypertension, diabetes mellitus, hyperlipidemia, trauma, and genetic factors. A 32-year-old man with familial Hirschsprung disease at the age of 2 presented cerebellar ischemic stroke due to bilateral VA dissections. A stroke recurred within 17 days despite oral dual antiplatelet therapy. Bilateral VA dissections and recurrent dissections are related to genetic mutations associated with connective tissue diseases.
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2019 Category: Neurology Authors: Kota Sato, Ryo Sasaki, Yasuyuki Ohta, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Koji Abe Tags: Case Report Source Type: research
Stroke Awareness among Elderly Hypertensives in a Rural Area of Bangalore District, India
India faces a high and growing burden of hypertension, which is an important cerebrovascular risk factor, especially in elderly persons. Poor awareness contributes to delays in seeking health care, which is undesirable given the emergent nature of stroke. Literature regarding awareness in this subgroup of the population is scarce. Our objective was to assess awareness regarding cerebrovascular disease among elderly persons with hypertension residing in a rural area of Bangalore district, and estimate their individual risk of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2020 Category: Neurology Authors: Vivek Bhat, Thanmayi GS, Arvind Kasthuri Source Type: research
Feasibility, acceptability, and appropriateness of the phone based interventions under nurse guidance after stroke (pings) in ghana
PINGS is a clinical trial to evaluate a nurse-led mHealth technology - centered approach to maintaining BP control among recent stroke survivors with hypertension in Ghana. PINGS involves domiciliary BP self-monitoring, mobile phone consultations, phone alerts as reminders, and patient education via text messages. We assessed the feasibility, acceptability, and appropriateness of PINGS from the perspective of health workers in general - not necessarily working in stroke rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Melvin K. Agbogbatey, Fred S. Sarfo, Alexis Beyuo, Kwaku Duah, Patrick Agasiya, Raelle Tagge, Bruce Ovbiagele, John H. Amuasi Source Type: research
National health insurance scheme: a means to effective stroke prevention among hypertensives in subsaharan africa
Uncontrolled hypertension is a leading cause of stroke in Sub-Saharan Africa. Factors affecting blood pressure control include low income, sedentary lifestyle and unhealthy diet. We sought to determine the role of National Health Insurance Scheme (NHIS) in achieving good blood control among hypertensives in Ghana and Nigeria and thus prevention of stroke and other cardiovascular complications of uncontrolled hypertension.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: T.I.A. Oseni, B.F. Dele-Ojo, B. Paa-Kwesi, D. Fifi, C.P. Echieh, B.S. Alabi, B. Tayo Source Type: research
Nascent Lobar Microbleeds and Stroke Recurrences
Conclusions: Though a cohort study limited the power of analyses, our findings suggested that lobar MBs might be associated with deep ICH.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Ikuhide Kohama, Kazuhisa Yoshifuji, Tatsufumi Nomura, Katsuya Komatsu Tags: Original Articles Source Type: research
Protective Effect of Telmisartan Against Progressive Oxidative Brain Damage and Synuclein Phosphorylation in Stroke-resistant Spontaneously Hypertensive Rats
Previously, we reported that reactive oxygen species and signaling molecules of angiotensin II produced lipid peroxides, degenerated proteins, and injured DNA after cerebral ischemia in normotensive Wistar rats. Here, we investigated the long-term effect of the angiotensin II type I receptor blocker telmisartan on oxidative stress and hyperphosphorylated α-synuclein accumulation in stroke-resistant spontaneously hypertensive rats (SHR-SR). At the age of 3 months, SHR-SR were divided into 3 treatment groups: SHR-SR vehicle (SHR/Ve), SHR-SR low-dose telmisartan (.3 mg/kg/day) (SHR/low), and SHR-SR high-dose telmisartan (3...
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Yusuke Fukui, Toru Yamashita, Tomoko Kurata, Kota Sato, Violeta Lukic, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research
Telmisartan Reduces Progressive Oxidative Stress and Phosphorylated α-Synuclein Accumulation in Stroke-resistant Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion
We examined the effects of telmisartan on oxidative stress by advanced glycation end product (AGE) and 4-hydroxynonenal (4-HNE) assays and the accumulation of phosphorylated α-synuclein (pSyn) in the brain of stroke-resistant spontaneously hypertensive rats (SHR-SR). At the age of 12 weeks, SHR-SR received transient middle cerebral artery occlusion (tMCAO) for 90 minutes and were divided into the following 3 groups: the vehicle group, the low-dose telmisartan group (.3 mg/kg/day), and the high-dose telmisartan group (3 mg/kg/day, postoperatively). Immunohistologic analysis was performed when rats were 6, 12, and 18 m...
Source: Journal of Stroke and Cerebrovascular Diseases - April 28, 2014 Category: Neurology Authors: Kota Sato, Toru Yamashita, Tomoko Kurata, Violeta Lukic, Yusuke Fukui, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research
Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African Americans with Ischemic Stroke
Conclusions: Prevalence of LVSD in AA with IS was 22% in our study. Smoking was a significant modifiable RF associated with systolic dysfunction. A history of smoking and higher age could predict the occurrence of LVSD. There were more large-vessel IS in patients with LVSD.
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2014 Category: Neurology Authors: Saravana Devulapalli, Shariff Dunlap, Nakia Wilson, Stephen Cockburn, Mohankumar Kurukumbi, Prafulla Mehrotra, Annapurni Jayam-Trouth Tags: Original Articles Source Type: research
Strong Reduction of Low-Density Lipoprotein Receptor/Apolipoprotein E Expressions by Telmisartan in Cerebral Cortex and Hippocampus of Stroke Resistant Spontaneously Hypertensive Rats
Conclusions: These findings suggest that a long-term treatment with telmisartan directly improved neuronal lipid metabolism in the cerebral cortex and hippocampus of SHR-SR, mainly improving LDL-R and ApoE metabolism (SHR/Low) with a small additive benefit by BP lowering (SHR/High), which could provide a preventative approach in patients with hypertension at risk of Alzheimer disease.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2014 Category: Neurology Authors: Yun Zhai, Toru Yamashita, Tomoko Kurata, Yusuke Fukui, Kota Sato, Syoichiro Kono, Wentao Liu, Yoshio Omote, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Tags: Original Articles Source Type: research
Posterior Reversible Encephalopathy Syndrome and Stroke after Intravenous Immunoglobulin Treatment in Miller–Fisher Syndrome/Bickerstaff Brain Stem Encephalitis Overlap Syndrome
The association of a posterior reversible encephalopathy syndrome (PRES) without arterial hypertension with autoimmune-mediated inflammatory neuropathies such as Guillain–Barré syndrome (GBS) is a rare and poorly understood phenomenon. To date, PRES has been described as initial manifestation, coincidental finding, or adverse event subsequent to immunomodulatory treatment with intravenous immunoglobulin (IVIG) in cases of axonal and demyelinating GBS as well as in Miller–Fisher syndrome (MFS). We here report a case of MFS/Bickerstaff brain stem encephalitis (BBE)–overlap syndrome and nonhypertensive PRES that occurr...
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2014 Category: Neurology Authors: Henning R. Stetefeld, Helmar C. Lehmann, Gereon R. Fink, Lothar Burghaus Tags: Case Reports Source Type: research
Long-term Amelioration of Telmisartan on Metabolic Syndrome-related Molecules in Stroke-resistant Spontaneously Hypertensive Rat after Transient Middle Cerebral Artery Occlusion
We examined the effects of telmisartan on metabolic syndrome-related molecules such as insulin receptor (IR), peroxisome proliferator-activated receptor gamma (PPAR-γ), and angiotensin 2 type 1 receptor (AT1R) in stroke-resistant spontaneously hypertensive rat (SHR-SR) after transient middle cerebral artery occlusion (tMCAO), by administering telmisartan at either 0 (vehicle), .3 mg/kg/day (low dose), or 3 mg/kg/day (high dose), postoperatively, from 3 months of age and performed immunohistologic analysis at 6, 12, and 18 months of age.
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2014 Category: Neurology Authors: Kentaro Deguchi, Tomoko Kurata, Yusuke Fukui, Wentao Liu, Zhai Yun, Yoshio Omote, Kota Sato, Syoichiro Kono, Nozomi Hishikawa, Toru Yamashita, Koji Abe Source Type: research
Do Physically Active Patients Have Better Functional Outcome after Stroke? A Systematic Review
Stroke is one of the major causes of mortality and, among survivors, disability. Physical activity has a protective effect maybe due to a major control of risk factors, such as hypertension, diabetes mellitus, and body weight. However, the effect of prestroke physical activity and the poststroke functional outcomes needs clarification.
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2015 Category: Neurology Authors: Mariely Trigo Tumasz, Tathiana Trócoli, Matheus Fernandes de Oliveira, Ricardo Rezende Campos, Ricardo Vieira Botelho Source Type: research
A Fall in Systolic Blood Pressure 24 Hours after Thrombolysis for Acute Ischemic Stroke Is Associated with Early Neurological Recovery
The objective of this study is to investigate whether fall in systolic blood pressure (SBP) has any relationship with neurological outcome 24 hours after thrombolysis, after adjusting for potentially confounding factors.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2016 Category: Neurology Authors: Dipender Gill, Thomas Cox, Adarsh Aravind, Peter Wilding, Eleni Korompoki, Roland Veltkamp, Arindam Kar Source Type: research
Risk Factors of Nicardipine-Related Phlebitis in Acute Stroke Patients
Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis. We aimed to identify the incidence and risk factors of phlebitis in such patients.
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2016 Category: Neurology Authors: Kei Kawada, Tsuyoshi Ohta, Koudai Tanaka, Naoto Kadoguchi, Souichi Yamamoto, Masanori Morimoto Source Type: research
