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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hypertension

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Total 220 results found since Jan 2013.

Clinical Utility of the Inflammatory Factors Combined With Lipid Markers in the Diagnostic and Prognostic Assessment of Ischemic Stroke: Based on Logistic Regression Models
In this study, we developed novel logistic regression models for the diagnostic and prognostic assessment of ischemic stroke. Methods: A total of 288 ischemic stroke patients and 300 controls admitted to The First Affiliated Hospital of Soochow University were included in the testing group. Two validation groups from The Affiliated Kunshan Hospital of Jiangsu University and The Second Affiliated Hospital of Soochow University were included to assess our novel assessment models. Results: Results from the testing group indicated that the diagnostic assessment model for ischemic stroke prediction was: Logit(P)  = 437.116â...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2020 Category: Neurology Authors: Zhaoxi Ma, Yushan Yue, Yan Luo, Wanhua Wang, Yongjun Cao, Qi Fang Source Type: research

Coffee Consumption and Stroke Risk: Evidence from a Systematic Review and Meta-Analysis of more than 2.4 Million Men and Women
Stroke remains the leading cause of disability and mortality globally. Based on the Global Burden of Disease Study 2016, it was estimated that there were 13.7 million new stroke cases, 5.5 million deaths, 80.1 million prevalent cases, and 116.4 million disability-adjusted life-years.1 About 75% of stroke cases are ischemic, whereas the remaining cases are hemorrhagic.2 Stroke incidence increases with age. Well-known risk factors for stroke include personal history of hypertension, diabetes and cardiac diseases, unhealthy behavioral factors (heavy cigarette consumption, less physical inactivity, poor diet), and serious environmental risks.
Source: Journal of Stroke and Cerebrovascular Diseases - November 11, 2020 Category: Neurology Authors: Chuan Shao, Hui Tang, Xiaoya Wang, Jiaquan He Source Type: research

Chronic Kidney Disease is A Biomarker Rather Than A Risk Factor for Stroke
Over the last approximate 15 years some have suggested that chronic kidney disease (CKD) is a risk factor for stroke in and of itself. The assertion that CKD is a risk factor for stroke requires more scrutiny. It is possible that CKD is a reflection of severity of conditions such as hypertension and diabetes that are themselves among the most treatable risk factors for stroke or it is possible that the effects of CKD change vascular and related physiological functions and therefor directly contribute to increased risk of stroke and it is also possible that treatments for advance CKD such has hemodialysis could contribute t...
Source: Journal of Stroke and Cerebrovascular Diseases - May 29, 2021 Category: Neurology Authors: Judy Dawod, Bruce M Coull Source Type: research

The correlation between testosterone and stroke and the mediating role of blood pressure: The Henan rural cohort study
Stroke is currently the 2nd leading global cause of death and imposes a heavy burden on socio-economic and human health.1,2 There are many factors affecting stroke, among which blood pressure (BP) plays an important role.3 Many studies have pointed to hypertension as a risk factor for stroke.4-6 A study has shown that the prevention and treatment of stroke can be achieved by appropriately lowering BP.7 Therefore, the relationship between BP and stroke is still worth elucidating.
Source: Journal of Stroke and Cerebrovascular Diseases - August 16, 2022 Category: Neurology Authors: Pengling Liu, Dandan Wei, Luting Nie, Keliang Fan, Qingqing Xu, Lulu Wang, Juan Wang, Yu Song, Mian Wang, Xiaotian Liu, Jian Hou, Songcheng Yu, Linlin Li, Chongjian Wang, Wenqian Huo, Caini Fan, Zhenxing Mao Source Type: research

Patent Foramen Ovale and Infarct Volume in Cryptogenic Stroke
Background: The causal relationship between patent foramen ovale (PFO) and stroke is controversial. We hypothesized that if PFO is a pathway of embolic source, there might be a correlation between PFO characteristics (ie, size or extent of shunt) and ischemic lesion burden (ie, infarct volume and number).Methods: From ischemic stroke patients admitted to Asan Medical Center between January 2000 and October 2007, we identified those who had (1) acute ischemic lesion on diffusion-weighted imaging within 5 days of symptom onset and (2) cryptogenic stroke and only PFO detected by transesophageal echocardiography. PFO characte...
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2013 Category: Neurology Authors: Jin-Man Jung, Jong-Young Lee, Hye-Jin Kim, Youngrok Do, Sun U. Kwon, Jong S. Kim, Jae-Kwan Song, Dong-Wha Kang Tags: Original Articles Source Type: research

The Role of Classic Risk Factors and Prothrombotic Factor Gene Mutations in Ischemic Stroke Risk Development in Young and Middle-Aged Individuals
Background: In young individuals, a genetically predisposing hypercoagulability and classic modifying risk factors can act synergistically on the ischemic stroke risk development. The aim of the study was to compare the prevalence of classic vascular risk factors and polymorphisms of the G20210A coagulation factor II (prothrombin), Arg506Glu coagulation factor V Leiden, C677T methylenetetrahydrofolate reductase (MTHFR), and 4G/5G plasminogen activator inhibitor-1 (PAI-1) and the impact of these gene mutations and classic vascular risk factors on the overall stroke risk in individuals aged 55 years or younger.Methods: The s...
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2013 Category: Neurology Authors: Visnja Supanc, Zdenko Sonicki, Ines Vukasovic, Vesna V. Solter, Iris Zavoreo, Vanja B. Kes Tags: Original Articles Source Type: research

Ischemic Strokes in Pakistan: Observations from the National Acute Ischemic Stroke Database
Conclusions: Hypertension and dyslipidemia were the most common risk factors and large vessel atherosclerosis was the most common stroke etiology. Elderly patients were significantly more likely to have in-hospital complications, die during their hospital stay, and have a higher mRS score at discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2014 Category: Neurology Authors: Bhojo A. Khealani, Maria Khan, Muhammad Tariq, Abdul Malik, Alam I. Siddiqi, Safia Awan, Mohammad Wasay Tags: Original Articles Source Type: research

Safety of Standard-dose (.9-mg/kg) Alteplase Intravenous Thrombolysis for Acute Ischemic Stroke in Afro–Caribbeans, French West Indies
Conclusions: The excess hemorrhagic risk after standard-dose alteplase infusion into older Afro–Caribbean patients warrants further study to determine the possible role of cerebral microangiopathy and should be evaluated in different black populations.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Nicolas Chausson, Stéphane Olindo, Julien Joux, Martine Saint-Vil, Mathieu Aveillan, Didier Smadja Tags: Original Articles Source Type: research

Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan
Managing hypertension is crucial for preventing stroke recurrence. Some stroke patients experience resistant hypertension. In our experimental stroke model, olmesartan increased the expression of angiotensin (Ang) II converting enzyme-2. We hypothesized that switching to olmesartan affects biomarkers and the blood pressure (BP) in stroke patients whose BP is insufficiently controlled by standard doses of Ang II type I receptor blockers (ARBs) other than olmesartan.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2015 Category: Neurology Authors: Yoshiteru Tada, Kenji Yagi, Masaaki Uno, Nobuhisa Matsushita, Yasuhisa Kanematsu, Kazuyuki Kuwayama, Kenji Shimada, Kyoko Nishi, Motohiro Hirasawa, Junichiro Satomi, Keiko T. Kitazato, Teruyoshi Kageji, Eiji Matsuura, Shinji Nagahiro Source Type: research

Hypertension Severity, Race/Ethnicity and Stroke Recurrence Risk among Oldest Old Intracerebral Hemorrhage Survivors
Oldest old (age ≥80 years) survivors of Intracerebral Hemorrhage (ICH) may be at higher risk for stroke recurrence, reflecting increasing hypertension severity with aging. Because minority ICH survivors (African American and Hispanic) are at higher risk of stroke recurrence, oldest-old individuals in these racial /ethnic groups are likely to be at even higher risk. We sought to determine whether: 1) oldest old ICH survivors are at higher risk for stroke recurrence; and 2) minority oldest-old ICH survivors are at even higher risk for recurrent stroke than age-matched white counterparts.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Axana Rodriguez-Torres Tags: Poster 16 Source Type: research

Modifiable Factors Associated with Non-Adherence to Secondary Ischaemic Stroke Prevention Strategies
Eighty percent of stroke is due to five modifiable factors: hypertension, smoking, abdominal obesity, unhealthy diet, and lack of exercise.1 Risk factors for first-time and recurrent ischaemic stroke are similar.2 The absolute risk of a recurrent ischaemic stroke following an initial ischaemic stroke is 29.7% by five years.3 Recurrent strokes are associated with greater disability and mortality than first-time strokes.4 Secondary prevention strategies are key in reducing recurrent ischaemic events.
Source: Journal of Stroke and Cerebrovascular Diseases - October 27, 2020 Category: Neurology Authors: G Shankari, Szu Chyi Ng, Si Ying Goh, Fung Peng Woon, Kinjal Doshi, Pei Shieen Wong, Qianqian Fan, Il Fan Tan, Kaavya Narasimhalu, Deidre Anne De Silva Source Type: research

Factors Linked to Chronic Kidney Disease Among Stroke Survivors in Ghana
Stroke and chronic kidney disease (CKD) are major health problems across several regions of the globe. The Global Burden of Disease (GBD) collaborators have estimated the global lifetime risk of stroke for adults 25 years or older at 24.9% in 2016.1 An estimated 11-13% of the population worldwide has kidney disease.2 Both stroke and renal disease share traditional vascular risk factors such as hypertension, diabetes, obesity, dyslipidemia and obesity.3 Among ischemic stroke patients, 20% to 35% have CKD4,5 while 20 to 46% of patients with acute intracerebral hemorrhage have CKD.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Martin Agyei, Isaac Ogyefo, Priscilla Abrafi Opare-Addo, Bruce Ovbiagele Source Type: research

RNA binding protein RPS3 mediates microglial polarization by activating NLRP3 inflammasome via SIRT1 in ischemic stroke
Stroke remains the leading cause of death and permanent disability worldwide and ischemic stroke represents 80% of all cases, which brings extremely serious consequences to the family and society.1 Ischemic stroke refers to the general term of cerebral blood supply artery stenosis or occlusion leading to cerebral blood circulation disorder, insufficient blood supply and brain tissue necrosis.2 Cerebral ischemic stroke occurs in middle-aged and elderly people, and arteriosclerosis and hypertension are the main pathogenic factors.
Source: Journal of Stroke and Cerebrovascular Diseases - April 21, 2023 Category: Neurology Authors: Dimi Zhou, Lin Chen, Yuzheng Wang, Lu Gan, Mei Yuan, Lei Zhang, Fenfang Chen Source Type: research

Association of serum uric acid with risk of stroke in US adults: A cross-sectional study from NHANES 1999 –2020
Stroke is the second-most global death cause, only after ischemic heart disease, and third-most contributor to disability1, making it a major therapeutic challenge. More than 100 million individuals worldwide experience stroke every year, of which 795,000 cases are in the United States.2 Therefore, improved preventive strategies are needed; particularly, strategies targeting the modifiable risk factors of stroke, such as hypertension, hyperglycemia, and dyslipidemia, may help prevent more than approximately 90% of stroke cases.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2023 Category: Neurology Authors: Bei Gao, Yun Bao, Min Meng, Lijun Yu, Yali Lu, Rina Sa, Xiaoyan Liang, Jie Shi Source Type: research

Factors Associated with SF-12 Physical and Mental Health Quality of Life Scores in Adults with Stroke
Conclusions: Sociodemographic, comorbidity, and stroke-related disability factors have differential effect on physical and mental aspects of QOL in poststroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2011 Category: Neurology Authors: Charles Ellis, Anouk L. Grubaugh, Leonard E. Egede Tags: Original Articles Source Type: research