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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hypertension

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Total 220 results found since Jan 2013.

Incidence, Mortality, and Risk Factors for Oral Anticoagulant–associated Intracranial Hemorrhage in Patients with Atrial Fibrillation
Warfarin, a vitamin K epoxide reductase inhibitor, is the oral anticoagulant most commonly used to reduce the risk of stroke in patients with atrial fibrillation (AF). Warfarin has proved to be efficacious for this purpose in multiple clinical trials. However, warfarin use is laborious and associated with an increased risk of intracranial hemorrhage (ICH). Various factors increase the risk of warfarin-related ICH, including older age, intensity of anticoagulation, hypertension, and history of cerebrovascular disease.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2014 Category: Neurology Authors: Rebbeca Grysiewicz, Philip B. Gorelick Tags: Review Article Source Type: research

Relation between Cardiovascular Disease Risk Markers and Brain Infarcts Detected by Magnetic Resonance Imaging in an Elderly Population
Established cardiovascular risk markers, such as hypertension, are associated with increased risk of brain infarcts. The newer markers N-terminal pro-brain natriuretic peptide, troponin I, C-reactive protein, and cystatin C may affect the risk of cardiovascular events and potentially, thereby, also stroke. We investigated the association between established and new risk markers for cardiovascular disease and brain infarcts detected by magnetic resonance imaging (MRI) at age 75.
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2014 Category: Neurology Authors: Ruta Nylander, Lars Lind, Johan Wikström, Bertil Lindahl, Per Venge, Anders Larsson, Johan Ärnlöv, Lars Berglund, Håkan Ahlström, Lars Johansson, Elna-Marie Larsson Source Type: research

Identification of Plasma Biomarkers of Human Intracerebral Hemorrhage Subtypes through Microarray Technology
Intracerebral hemorrhage (ICH) is a devastating form of stroke and depending on the underlying cause, primary ICH is mainly caused by hypertension (HTN-ICH) or cerebral amyloid angiopathy (CAA-ICH). Currently, neuroimaging markers are required to identify the pattern for each etiology. The discovery of new biomarkers to improve the management of this pathology is therefore needed.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2015 Category: Neurology Authors: Cristina Merino-Zamorano, Pilar Delgado, Sofía Fernández de Retana, Israel Fernández-Cadenas, David Rodríguez-Luna, Joan Montaner, Mar Hernández-Guillamon Source Type: research

Clinical and Radiological Predictors of Malignant Middle Cerebral Artery Infarction Development and Outcomes
Optic nerve sheath diameter (ONSD) can predict intracranial hypertension and outcomes in severe traumatic brain injury. Its utility in middle cerebral artery (MCA) stroke is unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2017 Category: Neurology Authors: Angelique F. Albert, Matthew A. Kirkman Source Type: research

Huge Free-Floating Thrombus in the Internal Carotid Artery
A 70-year-old male patient presented with very short recurrent speech difficulty and left-sided monocular transient visual loss. The patient was diagnosed with Crohn's disease and had hemicolectomy due to obstruction 10 years ago. He also had a history of coronary artery disease, hypertension, left femoral vein thrombosis, and 50-pack-year smoking. He had no stroke attack before. He was taking regularly dual antiplatelet therapy and azathioprine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Uygur Tanriverdi, Osman Kizilkilic, Birsen Ince Tags: Letter to the Editor Source Type: research

Cerebral Vasculopathy in Coarctation of Aorta-a Rare Association
Coarctation of aorta is a rare congenital cardiovascular condition where patients are at risk of systemic arteriopathy, including hypertension and intracranial aneurysms.1 Here we report a rare case of young ischemic stroke, who was found to be having a cerebral vasculopathy and coarctation of aorta on evaluation.
Source: Journal of Stroke and Cerebrovascular Diseases - August 6, 2018 Category: Neurology Authors: Poornima Narayanan Nambiar, Arun K Nair, S. Vinayagamani, Sapna Erat Sreedharan, P N Sylaja Tags: Case Report Source Type: research

Transient Global Amnesia Secondary to Atherosclerotic Stenosis of Accessory Posterior Cerebral Artery
A 65-year-old woman was presented with a sudden onset of anterograde amnesia and iterative questioning after physical activity. Her past medical history included hypertension, diabetes, 2 symptomatic stroke events involving left temporal lobe infarction (Fig 1, A), and left basal ganglia infarction. There were no other positive neurological signs on this admission except for the previously right hemiparesis. At 3 days after onset, diffusion-weighted imaging (DWI) showed left hippocampal restricted diffusion foci (Fig 1, B).
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2019 Category: Neurology Authors: Zhiyong Zhang, Zhiqin Liu, Dantao Peng Tags: Case Study Source Type: research

Absence of Microbleeds Reduces the Risk for Recurrent Intracerebral Hemorrhage
Background: Many known risk factors, including hypertension and hyperlipidemia cause intracerebral hemorrhage (ICH). Recently, microbleeds have been identified as one of the factors leading to ICH. While some patients have been found to have recurrent ICH, risk factors for recurrent ICH are scarcely reported. We conducted an observational study on the risk-factors of recurrent ICH, comparing stroke patients with a single hemorrhagic episode and those with recurrent ICH. Methods: A retrospective analysis of a single-center database was performed to analyze the clinical presentation and characteristics of patients with a sin...
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2019 Category: Neurology Authors: Kenji Miki, Yoshihiro Natori, Yasutoshi Kai, Tetsuhisa Yamada, Megumu Mori, Naoki Noguchi, Hidenobu Koga Source Type: research

Hypertension is a Leading Cause of Nontraumatic Intracerebral Hemorrhage in Young Adults
Objective: To evaluate the etiology and discharge outcome of nontraumatic intracerebral hemorrhage (ICH) in young adults admitted to a comprehensive stroke center. Methods: A retrospective chart review was performed on patients with a discharge diagnosis of nontraumatic ICH admitted from 7/1/2011 to 6/30/2016. Data was collected on demographics, clinical history, ICH score, hemorrhage location, do-not-resuscitate (DNR) orders, likely etiology, and discharge disposition. Categorical data was reported as percentage.
Source: Journal of Stroke and Cerebrovascular Diseases - February 27, 2020 Category: Neurology Authors: Matthew Broderick, Luca Rosignoli, Abhishek Lunagariya, Nandakumar Nagaraja Source Type: research

Reach Out: Recruitment in a multicomponent, mobile health, behavioral intervention to reduce blood pressure in the Emergency Department patient population.
Hypertension is the most important modifiable risk factor for cardiovascular disease and an important contributor to the racial disparities of stroke. The Emergency Department (ED) may represent an opportunity to identify difficult-to-reach hypertensive populations.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Candace Odelia Whit Tags: Poster 19 Source Type: research

Impact of Race-Ethnic and Economic Disparities on Rates of Vascular Dementia in the National Inpatient Sample Database from 2006-2014
We have previously reported regional differences in the rates of vascular dementia (VD) in the United States (US), with the West having lower rates of VD diagnosis found in the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (NIS) Database. We aimed to determine if these regional differences were associated with race-ethnic disparities in economic status or prevalence of the stroke risk factors hypertension, diabetes, and hyperlipidemia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Alexis Netis Simpkins Tags: Poster 10 Source Type: research

An Enriched Environment Leads to Increased Synaptic Plasticity-Associated miRNA Levels after Experimental Subarachnoid Hemorrhage
Subarachnoid hemorrhage is a type of stroke caused by usually bleeding in the subarachnoid space with high morbidity and mortality.1,2 The cause is usually arterial aneurysm rupture and arterial hypertension. SAH also affects cognitive functions. Half of the patients may return to their daily lives in a year after SAH, but most of these patients often have problems in memory, executive functions, and speech functions in the future.3 Although long-term neurological disorders are thought to be caused by late-term cerebral ischemia due to vasospasm triggered by extravascular blood contact with the arteries, the molecular basi...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2021 Category: Neurology Authors: Fulya Buge Ergen, Didem Turgut Cosan, Turan Kandemir, İlknur Dag, Fezan Mutlu, Tevfik Erhan Cosan Source Type: research

Non-Adherence to Antihypertensive Guidelines in Patients with Asymptomatic Carotid Stenosis
Hypertension and carotid stenosis are both risk factors for stroke, but the presence of carotid stenosis might dampen enthusiasm for tight control of hypertension because of concerns for hypoperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: William Haley, Fayaz Shawl, W. Charles Sternbergh, Tanya N. Turan, Kevin Barrett, Jenifer Voeks, Thomas Brott, James F. Meschia Source Type: research

Volume of White Matter Hyperintensities, and Cerebral Micro-Bleeds
White matter hyperintensities (WMH) indicate the presence of patchy hyper-intense areas visible on FLAIR-MRI.1,2 WMH are visible in several neurological conditions, (cerebral small vessel disease, dementia, mood and cognitive disorders)3 –5 and these are associated with other pathologies such as stroke and hypertension.6 Moreover, their prevalence increases in elderly subjects.7 However, Pantoni et al.8 speculated that the clinical significance of WMH is not completely defined, and only most severe degrees of WMH seem to have an effect on cognitive functions.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Antonella Balestrieri, Pierleone Lucatelli, Harman S. Suri, Roberto Montisci, Jasjit S. Suri, Max Wintermark, Alessandra Serra, Xiaoguang Cheng, Cheng Jinliang, Roberto Sanfilippo, Luca Saba Source Type: research

Could salt intake directly affect the cerebral microvasculature in hypertension?
Cerebral small vessel disease (CSVD) is a significant cause of stroke and dementia,1,2 as well as gait impairment and falls in the elderly.3 However, its pathophysiology is still poorly understood, and no specific treatment strategies exist.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2022 Category: Neurology Authors: Ana Monteiro, Pedro Castro, Gilberto Pereira, Carmen Ferreira, Cristina Duque, Farzaneh Sorond, Andrew Milstead, James P. Higgins, Jorge Pol ónia, Elsa Azevedo Source Type: research