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Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

The relationship between chemerin levels and carotid intima-media thickness in patients with ischemic stroke (P1.262)
Conclusions:Consequently, this study showed that serum chemerin levels may play role in atherosclerosis and ischemic stroke.Study Supported by: Fırat University (FÜBAP)Disclosure: Dr. Demir has nothing to disclose. Dr. Atas has nothing to disclose. Dr. Aytaç has nothing to disclose. Dr. Gonen has nothing to disclose. Dr. Erten has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Demir, C., Ataş, I., Aytac, E., Gonen, M., Erten, Z. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Premature atherosclerosis: A major contributor to early-onset ischemic stroke
Atherosclerosis is an age-dependent process. The prevalence of large-artery atherosclerosis in case series of ischemic stroke in young adults has been substantially less than in older adults.1–4 Historically, data on the role of atherosclerosis in early-onset stroke have been limited for a variety of reasons. First, multi-institutional studies often have inconsistent evaluations of the cerebral vasculature, particularly the intracranial circulation. Second, studies may not report evidence for proximal atherosclerosis less severe than necessary to meet criteria for etiology. Emerging data, however, show a high inciden...
Source: Neurology - April 1, 2013 Category: Neurology Authors: Kittner, S. J., Singhal, A. B. Tags: Stroke in young adults, Ultrasound, Prevalence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African American Population with Ischemic Stroke (P02.044)
CONCLUSIONS: In this study the prevalence of LVSD in AA population with ischemic stroke was 22.45%. Among these, there was correlation between location of stroke and severity of LVSD. However prospective randomized studies are needed to validate our results. Disclosure: Dr. Devulapalli has nothing to disclose. Dr. Dunlap has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Cockburn has nothing to disclose. Dr. Kurukumbi has nothing to disclose. Dr. Jayam-Trouth has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Devulapalli, S., Dunlap, S., Wilson, N., Cockburn, S., Kurukumbi, M., Jayam-Trouth, A. Tags: P02 Cerebrovascular Disease II Source Type: research

Relation of Intracranial Stenosis and Elevated Carotid Intimal Medial Thickness in Black Caribbean Ischemic Stroke Patients (P03.187)
CONCLUSIONS: Our preliminary results suggest that increased MCA velocity is independent elevated CIMT, a biomarker for atherosclerosis, in anterior circulation ischemic stroke in CBs. History of hypercholesterolemia appears to be an important risk factor in atherosclerosis in CBs. This data suggests further prospective studies of MCA stenosis mechanisms in CBs are warranted.Disclosure: Dr. Law has nothing to disclose. Dr. Hao has nothing to disclose. Dr. Rojas-Soto has nothing to disclose. Dr. Yu has nothing to disclose. Dr. Baird has received personal compensation for activities as a speaker at the International Conferenc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Law, S., Hao, Q., Rojas-Soto, D., Yu, H., Baird, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Amusia: Unique Presentation of Stroke (P6.261)
CONCLUSIONS:Even though music and speech are similar in principle and execution they are functions of different hemispheres of the brain. Unlike aphasia, anatomical localization of amusia has not been established but it is known that right non dominant hemisphere is concerned with musical ability. Impairment of musical ability in the presence of intact speech can be the only presenting finding in stroke. Their identification is the key to early and appropriate treatment.Study Supported by:NoneDisclosure: Dr. Ramchandani has nothing to disclose. Dr. Alsmaan has nothing to disclose. Dr. Schwarz has nothing to disclose. Dr. A...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramchandani, C., Alsmaan, F., Schwarz, H., Alkhoury, Z. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Pearls & Oy-sters: Cerebral venous air embolism after central catheter removal: Too much air can kill
A 95-year-old woman with a history of hypertension presented from a long-term care facility for altered mental status in the context of dehydration and hypoglycemia. Multiple attempts to obtain a peripheral IV failed, and a triple lumen catheter was placed into the right internal jugular vein using the Seldinger technique under ultrasound guidance. No complications followed the procedure. The patient was then rehydrated and given multiple ampules of D50, leading to prompt resolution of the hypoglycemia and improvement in her mental status. After resolution of symptoms, the central line was removed, with the head of the bed...
Source: Neurology - March 30, 2015 Category: Neurology Authors: Bartolini, L., Burger, K. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke, Embolism RESIDENT AND FELLOW SECTION Source Type: research

More to Atherosclerosis than Stenosis: Symptomatic Carotid Artery with Intraplaque Hemorrhage (P5.285)
Conclusions:Current guidelines only address the degree of arterial narrowing when recommending carotid revascularization procedures for secondary stroke prevention. The most recent AHA-ASA guideline advises against revascularization procedures in less than 50% CA stenosis. These guidelines do not account for plaque morphology that may predict a high risk of early stroke recurrence as demonstrated by our patient.Disclosure: Dr. Rai has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant. Dr. Leung has nothing to disclose. Dr. Madan ha...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rai, S., Thaler, D., Leung, L., Madan, N., Salehi, P. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Mediators of the Age Effect among Patients Treated with Carotid Artery Stenting: The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) (P02.017)
CONCLUSIONS: These data suggest that a longer carotid artery lesion length is a significant contributor to the increased risk of CAS in the elderly. However, attenuation of the age effect was modest, less than a 10% change in the hazard ratios. Other potential mediators such as tortuosity and atherosclerosis of the aortic arch and great vessels were not assessed. Non-anatomic factors that are more common with advancing age such as cerebral white matter disease and subclinical dementia were also not assessed and may play a role in how elderly patients respond to ischemic insults.Disclosure: Dr. Voeks has nothing to disclose...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Voeks, J., Farb, R., Heck, D., Roubin, G., Moore, W., Logan, W., Longbottom, M., Howard, G., Brott, T. Tags: P02 Cerebrovascular Disease II Source Type: research

Early Spontaneous Recanalization of Symptomatic Carotid Occlusion: When Should We Be Looking? (P01.238)
CONCLUSIONS: Spontaneous recanalization of an occluded carotid artery may occur in a subacute fashion. Clinical deterioration, even minor, should prompt an investigation into possible recanalization.Disclosure: Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclose. Dr. Prabhakaran has nothing to disclose. Dr. Song has received personal compensation in an editorial capacity for serving as Advocacy Editor for AAN.com.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Cutting, S., Conners, J., Prabhakaran, S., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research

Recurrent ischemic strokes and headaches originating from Lambl's excrescence (P2.273)
CONCLUSIONS: The association between recurrent strokes and late-age onset migraine with aura should raise clinical suspicion of a cardiogenic valvular etiology. Early TEE use is necessary to diagnose cardiac valvular strands like LE. LE associated with migraine headaches should prompt a treatment with anti-thrombotic agent. While anticoagulants and cardiothoracic surgery are indicated for recurrent strokes, a combined antiplatelet therapy was effective in our patient.Disclosure: Dr. Dumitrascu has nothing to disclose. Dr. Tsimerinov has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dumitrascu, O., Tsimerinov, E. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research