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Source: Translational Stroke Research
Condition: Subarachnoid Hemorrhage
Nutrition: Iron
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The Fate of Erythrocytes after Cerebral Hemorrhage
AbstractAfter a cerebral hemorrhage (intracerebral, subarachnoid, and intraventricular), extravasated blood contributes to both initial brain injury, via physical disruption and mass effect, and secondary injury, through the release of potentially neurotoxic and pro-inflammatory factors such as hemoglobin, iron, and peroxiredoxin-2. Erythrocytes are a major blood component and are a source of such damaging factors. Erythrolysis after cerebral hemorrhage releases potential neurotoxins, contributing to brain injury and edema. Alternatively, erythrocyte phagocytosis via microglia or macrophages may limit the spill of neurotox...
Source: Translational Stroke Research - January 23, 2022 Category: Neurology Source Type: research
