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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Subarachnoid Hemorrhage
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Total 235 results found since Jan 2013.
Plasma nitrite as an indicator of cerebral ischemia during extracranial/intracranial bypass surgery in moyamoya patients
Cerebral ischemia occurs in conditions such as ischemic stroke, subarachnoid hemorrhage, and traumatic brain injury. Nitric oxide (NO) plays a widely accepted role in ischemia.1 –5 The ability to provide sensitive, timely detection of cerebral ischemia from NO metabolite changes in mixed venous blood samples could be of significant clinical utility.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: James H. Silver, Richard A. Jaffe, Jaime R. L ópez Source Type: research
Rules About Rules – The 6-h CT Rule For Subarachnoid Hemorrhage
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Chakraborty and colleagues describe the cautionary tale of a patient who presented with a thunderclap headache concerning for a subarachnoid hemorrhage (SAH). A head computed tomographic scan (CT) done 4 h after the onset of the headache was interpreted as negative but the patient was ultimately found to have an aneurysmal SAH.1
Source: Journal of Stroke and Cerebrovascular Diseases - September 15, 2020 Category: Neurology Authors: Jonathan A. Edlow Source Type: research
Importance of CBF measurement to exclude concomitant cerebral infarction in the murine endovascular perforation SAH model
Subarachnoid hemorrhage (SAH) has a high morbidity and mortality rate.1 A few studies exist regarding improving the outcome after SAH, compared to ischemic stroke.1,2 Further experimental and clinical studies are necessary for developing a novel treatment strategy for SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - August 20, 2020 Category: Neurology Authors: Hirofumi Matsubara, Takahiko Imai, Tetsuya Yamada, Yusuke Egashira, Shinsuke Nakamura, Masamitsu Shimazawa, Toru Iwama, Hideaki Hara Source Type: research
An Enriched Environment Leads to Increased Synaptic Plasticity-Associated miRNA Levels after Experimental Subarachnoid Hemorrhage
Subarachnoid hemorrhage is a type of stroke caused by usually bleeding in the subarachnoid space with high morbidity and mortality.1,2 The cause is usually arterial aneurysm rupture and arterial hypertension. SAH also affects cognitive functions. Half of the patients may return to their daily lives in a year after SAH, but most of these patients often have problems in memory, executive functions, and speech functions in the future.3 Although long-term neurological disorders are thought to be caused by late-term cerebral ischemia due to vasospasm triggered by extravascular blood contact with the arteries, the molecular basi...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2021 Category: Neurology Authors: Fulya Buge Ergen, Didem Turgut Cosan, Turan Kandemir, İlknur Dag, Fezan Mutlu, Tevfik Erhan Cosan Source Type: research
Pediatric Case of Life-Threatening Stroke Caused by Reversible Cerebral Vasoconstriction Syndrome with Spontaneous Cervical Internal Carotid Artery Vasospasm: A Case Report
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute and severe headache, referred to as thunderclap, and transient segmental cerebral arterial vasoconstriction. The diagnostic criteria include 1) thunderclap headache with or without neurological deficits or seizures, 2) uniphasic course without new symptoms lasting for more than a month after clinical onset, 3) no evidence of aneurysmal subarachnoid hemorrhage, 4) normal or near-normal cerebrospinal fluid analysis findings, 5) multifocal segmental cerebral artery vasoconstriction on either catheter angiography or, indirectly, computed tomography ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2021 Category: Neurology Authors: Yu Fujii, Yoshiki Hanaoka, Toshihiro Ogiwara, Jun-ichi Koyama, Tetsuyoshi Horiuchi Tags: Case Report Source Type: research
Long-Term Cognitive Outcome following Aneurysmal Subarachnoid Haemorrhage
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating form of stroke associated with significant morbidity and mortality. Survivors of aSAH frequently suffer from cognitive impairment,1,2 however the prevalence, characteristics and impact of the cognitive dysfunction needs further study.
Source: Journal of Stroke and Cerebrovascular Diseases - November 10, 2021 Category: Neurology Authors: Ben Gaastra, Frederick Ewbank, William Tapper, Diederik Bulters, Ian Galea Source Type: research
Whole-Brain Permeability Analysis on Admission Improves Prediction of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is a subtype of hemorrhagic stroke with significant morbidity and mortality.1 Delayed cerebral ischemia (DCI), one of the most feared complications of aSAH, mostly occurs within 4-14 days (termed the DCI time window, DCITW) in approximately 30-40% of survivors of initial aneurysmal rupture and is a major contributor to subsequent death, poor function outcome, and prolonged stay in the intensive care unit and hospital,2,3 Prediction of the occurrence of DCI as early and precisely as possible is essential to improving the outcome of patients with aSAH.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Chao Zhang, Lei Feng, Feng You, Xintong Zhao, Xinggen Fang, Yunfeng Zhou Source Type: research
Modification by an aspiration catheter for vessel stretching in thrombectomy using a stent retriever in vitro
Endovascular mechanical thrombectomy (EVT) using a stent retriever (SR) is the current first-line treatment for acute ischemic stroke (AIS) due to large vessel occlusion with a high revascularization rate, better safety profile, and better clinical outcomes.1 –4 However, the widespread increase in SR use has alerted clinicians about complications after EVT because> 10% of thrombectomy procedures are associated with perioperative complications5 including distal embolization to a new territory (4 –6%), de novo stenosis of the target vessel (3.4%), vessel perforation (0.6–4.9%), vasospasm (3.9–23%), dissection (0.6–...
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Yasuhiko Nariai, Tomoji Takigawa, Akio Hyodo, Kensuke Suzuki Source Type: research
Influence of Experimental Subarachnoid Hemorrhage on Nicotine-induced Contraction of the Rat Basilar Artery in Relation to Nicotinic Acetylcholine Receptors, Calcium, and Potassium Channels
Conclusions: Nicotine-induced contraction of the rat basilar artery involved the CNS nAChR subfamily, skeletal muscle nAChR subfamily, and L-type Ca2+ channel pathways. SAH did not affect any of the subfamilies of nAChR, but the Ca2+ channel was reduced and the adenosine triphosphate–sensitive K+ channel was enhanced by SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2011 Category: Neurology Authors: Xu Ji, Aimin Wang, Cristina C. Trandafir, Kazuyoshi Kurahashi Tags: Original Articles Source Type: research
Evaluation of Misdiagnosed Cases of Subarachnoid Hemorrhage and Causal Factors for Misdiagnosis
Conclusions: Type 1 cases were mild, and diagnosis required detailed medical history analyses. Type 2 cases were severe and were diagnosed based on electrocardiographic and echocardiographic changes characteristic of SAH. Symptoms of type 3 cases included vomiting, and diagnosis required recognition of meningeal irritation syndrome and detailed medical history analyses.
Source: Journal of Stroke and Cerebrovascular Diseases - March 15, 2013 Category: Neurology Authors: Tetsuhisa Yamada, Yoshihiro Natori Tags: Original Articles Source Type: research
Sequence Variations in the von Hippel–Lindau Tumor Suppressor Gene in Patients with Intracranial Aneurysms
Conclusions: There is accumulating evidence for a genetic basis of aneurysm development. Our investigations lead to the conclusion that the VHL gene is potentially involved in the formation of intracranial aneurysms in a subset of patients. Additional candidate genes need to be identified in order to develop sensitive genetic screening for at-risk patients.
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2013 Category: Neurology Authors: Jan-Helge Klingler, Marie T. Krüger, Johannes R. Lemke, Cordula Jilg, Vera Van Velthoven, Josef Zentner, Hartmut P.H. Neumann, Sven Gläsker Tags: Original Articles Source Type: research
Haptoglobin Phenotype Predicts Cerebral Vasospasm and Clinical Deterioration after Aneurysmal Subarachnoid Hemorrhage
Vasospasm (VS) and delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) are thought to greatly affect prognosis. Haptoglobin (Hp) is a hemoglobin-binding protein expressed by a genetic polymorphism (1-1, 2-1, and 2-2). Our objects were to investigate whether the Hp phenotype could predict the incidence of cerebral infarction, favorable outcome, clinical deterioration by DCI, and angiographical VS after aneurysmal SAH. Ninety-five consecutive patients who underwent clipping or coil embolization were studied. Favorable functional outcome was defined as a modified Rankin Scale score of 0-2 at 3 months. Angiogr...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Hiroyuki Ohnishi, Koji Iihara, Yasuyuki Kaku, Keita Yamauchi, Kenji Fukuda, Kunihiro Nishimura, Michikazu Nakai, Tetsu Satow, Norio Nakajima, Masaya Ikegawa Tags: Original Articles Source Type: research
Angiogram-Negative Subarachnoid Hemorrhage: Outcomes Data and Review of the Literature
We report data for 31 patients who presented to our institution from 2006 to the present. We performed a retrospective chart review, and report outcome data that include rates of rehemorrhage, hydrocephalus, vasospasm, permanent ischemic deficits, headaches, and outcomes based on modified Rankin Scale scores. We also performed a review of the literature and meta-analysis of the data therein. We compared rates of complications in the PMH subgroup and the diffuse-type hemorrhage subgroup. The chart review revealed no poor outcomes and no rehemorrhages in the patients with PMH. In the diffuse hemorrhage subgroup, 1 patient ha...
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2012 Category: Neurology Authors: Scott Boswell, William Thorell, Steve Gogela, Elizabeth Lyden, Dan Surdell Tags: Original Articles Source Type: research
Influence of Experimental Subarachnoid Hemorrhage on Nicotine-induced Contraction of the Rat Basilar Artery in Relation to Arachidonic Acid Metabolites Signaling Pathway
Conclusions: One week after exposure to SAH, PLC, sPLA2, and COX-2 activity were enhanced and cPLA2 activity was inhibited. One hour after exposure to SAH, PLC activity was enhanced and cPLA2 and iPLA2 activity was inhibited. Such changes of inflammatory arachidonic acid metabolites by smoking after SAH may play important roles in fatal cerebral circulatory disorders, suggesting important implications for the etiology and pathogenesis of SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - January 3, 2012 Category: Neurology Authors: Xu Ji, Aimin Wang, Cristina C. Trandafir, Kazuyoshi Kurahashi Tags: Original Articles Source Type: research
Hypocortisolism in Noncomatose Patients during the Acute Phase of Subarachnoid Hemorrhage
Background: Hypopituitarism represents a common long-term complication of subarachnoid hemorrhage (SAH). The incidence of hypocortisolism may be higher during the acute phase of SAH. Although hypocortisolism may be harmful in critically ill SAH patients, data are still lacking. The primary objective of this study was to investigate the incidence of hypocortisolism during the acute phase of SAH (15 days). Secondary objectives included an analysis of the relationship between hypocortisolism and outcome and the computation of the cortisol-time secretion curve.Methods: Clinical data of a consecutive series of 26 noncomatose pa...
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Luigi A. Lanterna, Veronica Spreafico, Paolo Gritti, Flavia Prodam, Antonio Signorelli, Francesco Biroli, Gianluca Aimaretti Tags: Original Articles Source Type: research
