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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Subarachnoid Hemorrhage
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Total 235 results found since Jan 2013.
TSG-6 Attenuates Oxidative Stress-Induced Early Brain Injury in Subarachnoid Hemorrhage Partly by the HO-1 and Nox2 Pathways
Aneurysmal subarachnoid hemorrhage (SAH) with high mortality and morbidity is a serious disease threat to human health.1,2 Cerebral vasospasm has been considered as the primary cause of poor prognosis after SAH in the past several years.3 However, recent studies have demonstrated that alleviated vasospasm cannot minimize brain injury after SAH.4 Early brain injury (EBI) occurring within 72 h has been reported as one of the major pathophysiological mechanisms after SAH. During EBI, intracranial pressure is increased and the cerebral blood flow is disrupted, which results in brain edema, blood-brain barrier (BBB) disruption ...
Source: Journal of Stroke and Cerebrovascular Diseases - September 8, 2020 Category: Neurology Authors: Xifeng Li, Wenchao Liu, Ran Li, Shenquan Guo, Haiyan Fan, Boyang Wei, Xin Zhang, Xuying He, Chuanzhi Duan Source Type: research
Development of Internal Carotid Artery Dissection During Masturbation
Sexual intercourse is known as one of the daily activities triggering spontaneous cervicocephalic artery dissection (sCAD), however, it has been unclear if masturbation can trigger the development of sCAD. Herein, we report a case of sCAD in association with masturbation. A 51-year-old right-handed man developed subarachnoid hemorrhage during masturbation. The dissection of the left internal carotid artery was evident on the 9th hospital day. Finally, he was treated with stenting and coiling and discharged with a good prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - November 11, 2020 Category: Neurology Authors: Masahiro Oomura, Takumi Kitamura, Kenichi Adachi, Yusuke Nishikawa, Mitsuhito Mase Tags: Case Report Source Type: research
Mean Platelet Volume may not be a Marker for Prognosis in Patients with Aneurysmal Subarachnoid Hemorrhage
Dear Editor,
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2020 Category: Neurology Authors: Cengiz Beyan, Esin Beyan Tags: Letter to the Editor Source Type: research
External Validation of the PHASES Score in Patients with Multiple Intracranial Aneurysms
This study sought to assess whether the Population, Hypertension, Age, Size, Earlier Subarachnoid Hemorrhage, Site (PHASES) score can do risk stratification of patients with multiple aneurysms (MIAs).
Source: Journal of Stroke and Cerebrovascular Diseases - February 23, 2021 Category: Neurology Authors: Xin Feng, Xin Tong, Jigang Chen, Fei Peng, Hao Niu, Jiaxiang Xia, Xiaoxin He, Peng Qi, Jun Lu, Yang Zhao, Weitao Jin, Zhongxue Wu, Yuanli Zhao, Aihua Liu, Daming Wang Source Type: research
Enigma of what is Known about Intracranial Aneurysm Occlusion with Endovascular Devices
Aneurysmal subarachnoid Hemorrhage is a major cause of neurological morbidity and mortality. Over the years vascular neurosurgery has witnessed technological advances aimed to reduce the morbidity and mortality. Several endovascular devices have been used in clinical practice to achieve this goal in the management of ruptured and unruptured cerebral aneurysms. Recurrence due to recanalization is encountered in all of these endovascular devices as well as illustrated by Barrow Ruptured Aneurysm Trial.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2021 Category: Neurology Authors: Adesh Shrivastava, Rakesh Mishra, Luis Rafael Moscote Salazar, Pradeep Chouksey, Sumit Raj, Amit Agrawal Source Type: research
Ultra-Early Induction of General Anesthesia for Reducing Rebleeding Rates in Patients with Aneurysmal Subarachnoid Hemorrhage
Rebleeding of aneurysmal subarachnoid hemorrhage (aSAH) is one of the significant risk factors for poor clinical outcome. The rebleeding risk is the highest during the acute phase with an approximate rebleeding rate of 9-17% within the first 24 h. Theoretically, general anesthesia can stabilize a patient's vital signs; however, its effectiveness as initial management for preventing post-aSAH rebleeding remains unclear. The purpose of this study was to determine the feasibility and safety of ultra-early general anesthesia induction for reducing the rebleeding rates among patients with aSAH.
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2021 Category: Neurology Authors: Junya Kaneko, Takashi Tagami, Chie Tanaka, Kentaro Kuwamoto, Shin Sato, Ami Shibata, Saori Kudo, Akiko Kitahashi, Masamune Kuno, Shoji Yokobori, Kyoko Unemoto Source Type: research
Spontaneous Subarachnoid Haemorrhage in Spinal Hemangioblastoma: Illustrative Case and Discussion of a Pathophysiological Hypothesis
Spontaneous non-aneurysmal subarachnoid haemorrhage (naSAH) is an unusual finding that could be burdened by significant mortality and morbidity rates. Rare pathologies and delayed diagnosis could be advocated as responsible of unfavourable outcomes. Herein, we describe an exceedingly rare giant lumbar spinal hemangioblastoma (80 × 23 mm) presenting as an intracranial naSAH. Based on our radiological and clinical findings a pathophysiological hypothesis linking intracranial naSAH to venous hypertension was discussed for the first time even among lumbar spinal tumors.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: Giacomo Bertolini, Alessia Fratianni, Alberto Luca Messina, Enrico Epifani, Matteo Fantoni, Pellegrino Crafa, Diego Mazzatenta, Roberto Menozzi, Ermanno Giombelli Source Type: research
Systemic Inflammation Response Index and Systemic Immune-inflammation Index for Predicting the Prognosis of Patients with Aneurysmal Subarachnoid Hemorrhage
An aneurysmal subarachnoid hemorrhage (aSAH) can result in disability and high mortality.1 Re-bleeding, poor admission neurologic status, thick SAH, vasospasm, and delayed cerebral ischemia (DCI) are known as predicting factors for exacerbated prognosis of aSAH.2 –5 Similar to other cerebrovascular diseases, aSAH can causes a pronounced peripheral inflammatory/immune response. Systemic changes are also associated with outcomes of patients with SAH.6,7 Although the exact mechanism has not yet been fully revealed, inflammation is known to plays an important role in the progress of aSAH by inducing early brain damage, vasos...
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2021 Category: Neurology Authors: Seonyong Yun, Ho Jun Yi, Dong Hoon Lee, Jae Hoon Sung Source Type: research
Involvement of Cerebral Blood Flow on Neurological and Behavioral Functions after Subarachnoid Hemorrhage in Mice
Subarachnoid Hemorrhage (SAH) has a high mortality rate of up to 40%,1 and often causes severe neurological sequel in survivors. Spontaneous SAH is caused by a ruptured intracranial aneurysm. Despite the evolution of less invasive treatments for ruptured aneurysms, such as endovascular coil embolization, the mortality and morbidity rates of SAH still remain high.2 Thus, it is important to establish novel treatment strategies that focus on cognitive decline following SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2021 Category: Neurology Authors: Hirofumi Matsubara, Takahiko Imai, Shohei Tsuji, Natsumi Oka, Takuya Ohba, Tetsuya Yamada, Yusuke Egashira, Shinsuke Nakamura, Masamitsu Shimazawa, Toru Iwama, Hideaki Hara Source Type: research
Admission Neutrophil to Lymphocyte Ratio for Predicting Outcome in Subarachnoid Hemorrhage
We sought to evaluate the relationship between admission neutrophil-to-lymphocyte ratio (NLR) and functional outcome in aneurysmal subarachnoid hemorrhage (aSAH) patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2021 Category: Neurology Authors: Jason J. Chang, Ehsan Dowlati, Matthew Triano, Enite Kalegha, Rashi Krishnan, Brittany M. Kasturiarachi, Leila Gachechiladze, Abhi Pandhi, Marios Themistocleous, Aristeidis H. Katsanos, Daniel R. Felbaum, Jeffrey C. Mai, Rocco A. Armonda, Edward F. Aulisi Source Type: research
Early Neurological Changes and Interpretation of Clinical Grades in Aneurysmal Subarachnoid Hemorrhage
Hunt and Hess (HH) and World Federation of Neurological Surgeons (WFNS) grades are commonly used to report clinical severity of aneurysmal subarachnoid hemorrhage (aSAH). We sought to determine the impact of early neurological changes and the timing of clinical grade assignment on the prognostication accuracy.
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2021 Category: Neurology Authors: Ali Mahta, Kayleigh Murray, Michael E. Reznik, Bradford B. Thompson, Linda C. Wendell, Karen L. Furie Source Type: research
Nicardipine Prolonged Release Implants for Prevention of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis
A paucity of treatments to prevent delayed cerebral ischemia (DCI) has stymied recovery after aneurysmal subarachnoid hemorrhage (aSAH). Nicardipine has long been recognized as a potent cerebrovascular vasodilator with a history off-label use to prevent vasospasm and DCI. Multiple centers have developed nicardipine prolonged release implants (NPRI) that are directly applied during clip ligation to locally deliver nicardipine throughout the vasospasm window. Here we perform a systematic review and meta-analysis to assess whether NPRI confers protection against DCI and improves functional outcomes after aSAH.
Source: Journal of Stroke and Cerebrovascular Diseases - August 5, 2021 Category: Neurology Authors: Feras Akbik, Hannah Waddel, Blessing N.R. Jaja, R. Loch Macdonald, Renee Moore, Owen B. Samuels, Ofer Sadan Source Type: research
Best Motor Response Predicts Favorable Outcome for “True” WFNS Grade V Patients with Aneurysmal Subarachnoid Hemorrhage
Preoperative neurological assessment provides critical information on the treatment for aneurysmal subarachnoid hemorrhage (aSAH) to predict the outcome and determine the surgical indication.1-5 Therefore, numerical scoring methods such as the Hunt& Hess scale,2 Hunt and Kosnik scale,1 and World Federation of Neurosurgical Societies (WFNS) scale6 have been proposed and established to describe temporary changes and estimate prognosis in an individual patient and to compare the management outcome in different patient groups.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2021 Category: Neurology Authors: Shinsuke Yoshida, Soichi Oya, Masaaki Shojima, Toru Matsui Source Type: research
Delayed Cerebral Ischemia after Subarachnoid Hemorrhage
Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with aSAH. Previously, large cerebral artery vasospasm was thought to be the sole major contributing factor associated with increased risk of DCI. Recent literature has challenged this concept. We conducted a literature search using PUBMED as the prime source of articles discussing various other factors which may contribute to the development of DCI both in the presence or absence of large cerebral artery vasospasm.
Source: Journal of Stroke and Cerebrovascular Diseases - August 28, 2021 Category: Neurology Authors: Asad Ikram, Muhammad Ali Javaid, Santiago Ortega-Gutierrez, Magdy Selim, Sarah Kelangi, Syed Muhammad Hamza Anwar, Michel T. Torbey, Afshin A. Divani Tags: Review Article Source Type: research
Fatty Acid-Binding Protein 3 and CXC-Chemokine Ligand 16 are Associated with Unfavorable Outcome in Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with activation of the inflammatory cascade contributing to unfavorable outcome and secondary complications, such as delayed cerebral ischemia (DCI). Both fatty acid –binding protein 3 (FABP3) and CXC-chemokine ligand 16 (CXCL-16) have been linked to vascular inflammation and cellular death. The authors aimed to assess the 30-day prognostic value of serum levels of FABP3 and CXCL-16 and explore their associations with DCI in aSAH patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 26, 2021 Category: Neurology Authors: Daniel Schranz, Tihamer Molnar, Szabina Erdo-Bonyar, Diana Simon, T ímea Berki, Laszlo Zavori, Alex Szolics, Andras Buki, Gabor Lenzser, Peter Csecsei Source Type: research
