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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Subarachnoid Hemorrhage

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Total 235 results found since Jan 2013.

Nonaneurysmal “Pseudo-Subarachnoid Hemorrhage” Computed Tomography Patterns: Challenges in an Acute Decision-Making Heuristics
Acute aneurysmal subarachnoid hemorrhage (SAH) is a medical and neurosurgical emergency from ruptured brain aneurysm. Aneurysmal SAH is identified on brain computed tomography (CT) as increased density of basal cisterns and subarachnoid spaces from acute blood products. Aneurysmal SAH-like pattern on CT appears as an optical illusion effect of hypodense brain parenchyma and/or hyperdense surrounding cerebral cisterns and blood vessels termed as “pseudo-subarachnoid hemorrhage” (pseudo-SAH).
Source: Journal of Stroke and Cerebrovascular Diseases - June 5, 2018 Category: Neurology Authors: Tasneem F. Hasan, Walter Duarte, Oluwaseun O. Akinduro, Eric D. Goldstein, Rebecca Hurst, Neil Haranhalli, David A. Miller, Robert E. Wharen, Rabih G. Tawk, William D. Freeman Source Type: research

Coil Embolization through Collateral Pathway for Ruptured Vertebral Artery Dissecting Aneurysm with Bilateral Vertebral Artery Occlusion
Intracranial vertebral artery dissecting aneurysm (VADA) is a well-known cause of subarachnoid hemorrhage (SAH). Endovascular treatment is now well established as an effective method for treating ruptured VADA, especially in the acute phase of SAH.1,2 Although stent technology has introduced a new strategy in the treatment of VADA, internal trapping of both the affected vertebral artery (VA) and the VADA using detachable coils is still the standard endovascular treatment for the acute phase of ruptured VADAs to prevent re-rupture.
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2018 Category: Neurology Authors: Satoshi Murai, Kenji Sugiu, Tomohito Hishikawa, Masafumi Hiramatsu, Shingo Nishihiro, Naoya Kidani, Yu Takahashi, Isao Date Tags: Case Studies Source Type: research

Therapeutically Targeting Platelet-Derived Growth Factor-Mediated Signaling Underlying the Pathogenesis of Subarachnoid Hemorrhage-Related Vasospasm
Vasospasm accounts for a large fraction of the morbidity and mortality burden in patients sustaining subarachnoid hemorrhage (SAH). Platelet-derived growth factor (PDGF)- β levels rise following SAH and correlate with incidence and severity of vasospasm.
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2018 Category: Neurology Authors: Michael George Zaki Ghali, Visish M. Srinivasan, Jeremiah Johnson, Peter Kan, Gavin Britz Tags: Review Article Source Type: research

Spontaneous Spinal Subarachnoid Hemorrhage: Presentation and Outcome
Spontaneous spinal subarachnoid hemorrhage (SSAH) is a rare but serious condition that can lead to a variety of medical complications.
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2018 Category: Neurology Authors: Micah D. Yost, Alejandro A. Rabinstein Source Type: research

Efficacy of Cilostazol in Prevention of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis
Cilostazol, a selective inhibitor of phosphodiesterase 3, may reduce symptomatic vasospasm and improve outcome in patients with aneurysmal subarachnoid hemorrhage considering its anti-platelet and vasodilatory effects. We aimed to analyze the effects of cilostazol on symptomatic vasospasm and clinical outcome among patients with aneurysmal subarachnoid hemorrhage (aSAH).
Source: Journal of Stroke and Cerebrovascular Diseases - August 6, 2018 Category: Neurology Authors: Hamidreza Saber, Aaron Desai, Mohan Palla, Wazim Mohamed, Navid Seraji-Bozorgzad, Muhammed Ibrahim Source Type: research

Electrocadiographic Scoring Helps Predict Left Ventricular Wall Motion Abnormality Commonly Observed after Subarachnoid Hemorrhage
Background: Cardiac wall motion abnormality (WMA) is a common complication in patients with subarachnoid hemorrhage (SAH) and is one determinant of their prognosis. The aim of this study was to examine whether the electrocardiography (ECG) findings at admission could predict WMA commonly observed after SAH. Materials and methods: We studied 161 SAH patients with SAH who were hospitalized in our institution between April 2007 and November 2010. We performed bedside 2-dimensional transthoracic echocardiography and 12-lead surface ECG within 24 hours of SAH onset.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2018 Category: Neurology Authors: Keiko Sugimoto, Akira Yamada, Joji Inamasu, Yuichi Hirose, Kayoko Takada, Kunihiko Sugimoto, Risako Tanaka, Eiichi Watanabe, Yukio Ozaki Source Type: research

Calpeptin Reduces Neurobehavioral Deficits and Neuronal Apoptosis Following Subarachnoid Hemorrhage in Rats
This study was undertaken to determine the effects of inhibition of calpain on neurological deficit and neuronal apoptosis following experimental SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2018 Category: Neurology Authors: You-dong Zhou, Li Cai Source Type: research

Efficacy of Thyrotropin-Releasing Hormone Analog for Protracted Disturbance of Consciousness due to Aneurysmal Subarachnoid Hemorrhage
Objective: The efficacy of thyrotropin-releasing hormone tartrate (TRH-T) for treating prolonged disturbance of consciousness due to aneurysmal subarachnoid hemorrhage (SAH) remains unclear. The purpose of the present study was to determine whether TRH-T was really effective, and what was the recovery factor when it was valid. This was a retrospective study of a single facility. Methods: We treated 208 patients with aneurysmal SAH at our hospital between 2011 and 2017. Among them, we investigated 97 cases in which TRH-T was administered to prolonged disturbance of consciousness.
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2019 Category: Neurology Authors: Ami Shibata, Fumihiro Matano, Yu Fujiki, Takayuki Mizunari, Yasuo Murai, Hiroyuki Yokota, Akio Morita Source Type: research

Subarachnoid Hemorrhage with Progressive Cerebral Steno-Occlusive Disease: Report of 2 Cases
Nontraumatic nonaneurysmal subarachnoid hemorrhage (SAH) is a rare condition. Among them, SAH with cerebral steno-occlusive disease is quite rare. Moreover there has been no report of SAH patient who had been diagnosed with steno-occlusive disease since before. We here report 2 cases of nontraumatic nonaneurysmal convexity SAH who originally had progressive cerebral steno-occlusive disease. Case 1, a woman in her 40s who had diagnosed left internal carotid artery (ICA) stenosis 6 years before complained of headache.
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2019 Category: Neurology Authors: Soichiro Takamiya, Tetsuyuki Yoshimoto, Katsuhiko Maruichi Tags: Case Report Source Type: research

Secular Increases in Spontaneous Subarachnoid Hemorrhage during Pregnancy: A Nationwide Sample Analysis
Importance: Understanding of the epidemiology, outcomes, and management of spontaneous subarachnoid hemorrhage (sSAH) during pregnancy is limited. Small, single center series suggest a slight increase in morbidity and mortality. Objective: To determine if incidence of sSAH in pregnancy is increasing nationally and also to study the outcomes for this patient population. Design, Setting, and Participants: A retrospective analysis was performed utilizing the Nationwide Inpatient Sample (NIS) and Healthcare Cost and Utilization Project for the years 2002-2014 for sSAH hospitalizations.
Source: Journal of Stroke and Cerebrovascular Diseases - January 30, 2019 Category: Neurology Authors: Kaustubh Limaye, Achint Patel, Mihir Dave, Cynthia Kenmuir, Sourabh Lahoti, Ashutosh P. Jadhav, Edgar A. Samaniego, Santiago OrtegaGutierrez, James Torner, David Hasan, Colin P. Derdeyn, Tudor Jovin, Harold P. Adams, Enrique C. Leira Source Type: research

Spontaneous Dissection of Both Vertebral Arteries Diagnosed with Three-Dimensional T1-Weighted Image
A 48-year-old woman spontaneously developed occipital pain, without any other neurological deficit. A brain magnetic resonance angiography showed narrowing, irregular dilatation, and aneurysmal formation in both the vertebral arteries (VA). According to these findings and the clinical course, we diagnosed the patient with spontaneous VA dissection. There was no finding suggesting cerebral infarction or subarachnoid hemorrhage. Three-dimensional T1-weighted magnetic resonance imaging performed 27days after first onset of headache revealed a crescent-shaped high-intensity lesion in both the VA walls.
Source: Journal of Stroke and Cerebrovascular Diseases - March 17, 2019 Category: Neurology Authors: Takanori Iwamoto, Naoki Oyama, Takaya Kitano, Toshiaki Goda, Junichi Uemura, Yoshiki Yagita Tags: Case Reports Source Type: research

Predictors for Functional Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage Who Completed In-Hospital Rehabilitation in a Single Institution
Background: Although many studies evaluated independent prognosis factors of functional outcome in patients with subarachnoid hemorrhage (SAH) at a suitable time point, some patients take a long time to get functional improvement. The purpose of this study is to evaluate predictors for functional outcome in SAH patients who underwent surgical clipping and in-hospital rehabilitation in our single institution using Modified Rankin Scale (MRS) and Barthel Index (BI). Methods: Two-hundred fifty-one SAH patients were admitted to our hospital from January 2008 to December 2017.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2019 Category: Neurology Authors: Yushin Takemoto, Yu Hasegawa, Akihito Hashiguchi, Koichi Moroki, Hajime Tokuda, Akitake Mukasa Source Type: research

Serum Glucose and Potassium Ratio as Risk Factors for Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage
Objective: Cerebral vasospasm is associated with poor prognosis in patients with aneurysmal subarachnoid hemorrhage (SAH), and biomarkers for predicting poor prognosis have not yet been established. We attempted to clarify the relationship between serum glucose/potassium ratio and cerebral vasospasm in patients with aneurysmal SAH. Methods: We studied 333 of 535 aneurysmal SAH patients treated between 2006 and 2016 (123 males, 210 females; mean age 59.7 years; range 24-93). We retrospectively analyzed the relationship between cerebral vasospasm grade and clinical risk factors, including serum glucose/potassium ratio.
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2019 Category: Neurology Authors: Fumihiro Matano, Yu Fujiki, Takayuki Mizunari, Kenta Koketsu, Tomonori Tamaki, Yasuo Murai, Hiroyuki Yokota, Akio Morita Source Type: research

Poor Utilization of Nimodipine in Aneurysmal Subarachnoid Hemorrhage
Objective: To determine adherence to nimodipine administration in patients admitted with aneurysmal subarachnoid hemorrhage (aSAH). Background: Oral nimodipine (60 mg every 4 hours for 21 days) is recommended by the national guidelines for aSAH. A Cochrane systematic review has determined that nimodipine reduces the risk of cerebral ischemia and is currently the only effective drug for the prevention of vasospasm in aSAH patients. Design/Methods: We retrospectively analyzed 109 patients with aSAH admitted to the Neurosciences Intensive Care Unit (NICU) at a tertiary care medical center between 2010 and 2013.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2019 Category: Neurology Authors: Arnavaz Hajizadeh Barfejani, Alejandro A. Rabinstein, Eelco F.M. Wijdicks, Sarah L. Clark Source Type: research

Early Prognostication of 1-Year Outcome After Subarachnoid Hemorrhage: The FRESH Score Validation
Background and Aim: The FRESH score is a tool to prognosticate long-term outcomes after spontaneous subarachnoid hemorrhage (SAH). Here, for the first time, we aimed to externally validate the disability part of FRESH using its original four score variables. Methods: A total of 107 patients with SAH were prospectively enrolled in the Yale Acute Brain Injury Biorepository between September 2014 and January 2018. 12-month functional outcome was recorded prospectively by trained study investigators using the modified Rankin Scale (mRS).
Source: Journal of Stroke and Cerebrovascular Diseases - July 17, 2019 Category: Neurology Authors: Jens Witsch, Lindsey Kuohn, Ryan Hebert, Branden Cord, Lauren Sansing, Emily J. Gilmore, David Y. Hwang, Nils Petersen, Guido J. Falcone, Charles Matouk, Kevin N. Sheth Source Type: research