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Specialty: Neuroscience
Condition: Hemorrhagic Stroke
Procedure: Transplants
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Total 2 results found since Jan 2013.
Carbon Monoxide Protects Neural Stem Cells Against Iron Overload by Modulating the Crosstalk Between Nrf2 and NF- κB Signaling
Neurochem Res. 2022 Mar 8. doi: 10.1007/s11064-022-03537-9. Online ahead of print.ABSTRACTAlthough accumulating evidences have demonstrated pro-survival effects of CO against various insults, the precise mechanism explaining how neural stem cells (NSCs) are protected by CO also remains largely unknown. Here we report CO pro-survival effect on NSCs against iron overload was comparable to that obtained with pharmacological inhibitors of reactive oxygen species (ROS). Its pro-survival effect was accompanied by the inhibition of ROS and subsequent inhibition of NF-κB which is mediated through nuclear factor erythroid 2-relate...
Source: Neurochemical Research - March 8, 2022 Category: Neuroscience Authors: Xie Zhengxing Hu Aiying Zhang Zongqiang Miao Zengli Source Type: research
