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Treatments for unruptured intracranial aneurysms
CONCLUSIONS: There is currently insufficient good-quality evidence to support either conservative treatment or interventional treatments (microsurgical clipping or endovascular coiling) for individuals with unruptured intracranial aneurysms. Further randomized trials are required to establish if surgery is a better option than conservative management, and if so, which surgical approach is preferred for which patients. Future studies should include consideration of important characteristics such as participant age, gender, aneurysm size, aneurysm location (anterior circulation and posterior circulation), grade of ischemia (...
Source: Cochrane Database of Systematic Reviews - May 10, 2021 Category: General Medicine Authors: Felipe Gomes de Barros Pontes Edina Mk da Silva Jose Cc Baptista-Silva Vladimir Vasconcelos Source Type: research

Endovascular coiling versus neurosurgical clipping for people with aneurysmal subarachnoid haemorrhage.
CONCLUSIONS: The evidence in this systematic review comes mainly from one large trial, and long-term follow-up is available only for a subgroup of participants within that trial. For people in good clinical condition with ruptured aneurysms of either the anterior or posterior circulation the data from randomised trials show that, if the aneurysm is considered suitable for both neurosurgical clipping and endovascular coiling, coiling is associated with a better outcome. There is no reliable trial evidence that can be used directly to guide treatment in people with a poor clinical condition. PMID: 30110521 [PubMed - as ...
Source: Cochrane Database of Systematic Reviews - August 15, 2018 Category: General Medicine Authors: Lindgren A, Vergouwen MD, van der Schaaf I, Algra A, Wermer M, Clarke MJ, Rinkel GJ Tags: Cochrane Database Syst Rev Source Type: research