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Source: Stroke
Condition: Hemorrhagic Stroke
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Total 995 results found since Jan 2013.
Selective NLRP3 (Pyrin Domain-Containing Protein 3) Inflammasome Inhibitor Reduces Brain Inȷury After Intracerebral Hemorrhage Basic Sciences
Conclusions—These results indicate that the NLRP3 inflammasome inhibitor, MCC950, attenuates brain injury and inflammation after ICH. Hence, NLRP3 inflammasome inhibition is a potential therapy for ICH that warrants further investigation.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Honglei Ren, Ying Kong, Zhijia Liu, Dongyun Zang, Xiaoxia Yang, Kristofer Wood, Minshu Li, Qiang Liu Tags: Intracranial Hemorrhage Original Contributions Source Type: research
Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space? Brief Report
Conclusions—Although IVH expansion does indeed occur in a minority of ICH nonexpanders, its inclusion into a revised hematoma expansion definition does not alter the predictive performance of the spot sign.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Dar Dowlatshahi, Anirudda Deshpande, Richard I. Aviv, David Rodriguez-Luna, Carlos A. Molina, Yolanda Silva Blas, Imanuel Dzialowski, Adam Kobayashi, Jean-Martin Boulanger, Cheemun Lum, Gordon J. Gubitz, Vasantha Padma, Jayanta Roy, Carlos S. Kase, Rohit Tags: Clinical Studies, Computerized Tomography (CT), Imaging, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Brief Reports Source Type: research
Prehospital Systolic Blood Pressure Is Related to Intracerebral Hemorrhage Volume on Admission Brief Report
Background and Purpose—Ultra-early blood pressure (BP) management in the prehospital setting could improve the efficacy of this treatment on attenuating intracerebral hemorrhage (ICH) expansion. We aimed to determine the association of prehospital systolic BP (SBP) with ICH volume, ultra-early hematoma growth, and the spot sign on admission.Methods—We conducted a retrospective study of a prospective database of 219 consecutive patients with spontaneous ICH admitted to the emergency department of a tertiary stroke center during a 3-year period. Prehospital SBP and ICH volume, ultra-early hematoma growth (ICH volume/onse...
Source: Stroke - December 22, 2017 Category: Neurology Authors: David Rodriguez–Luna, Noelia Rodriguez–Villatoro, Jesus M. Juega, Sandra Boned, Marian Muchada, Estela Sanȷuan, Jorge Pagola, Marta Rubiera, Marc Ribo, Pilar Coscoȷuela, Carlos A. Molina Tags: High Blood Pressure, Computerized Tomography (CT), Intracranial Hemorrhage Brief Reports Source Type: research
Cerebellar Hematoma Location Brief Report
Background and Purpose—Spontaneous cerebellar intracerebral hemorrhage (ICH) has been reported to be mainly associated with vascular changes secondary to hypertension. However, a subgroup of cerebellar ICH seems related to vascular amyloid deposition (cerebral amyloid angiopathy). We sought to determine whether location of hematoma in the cerebellum (deep and superficial regions) was suggestive of a particular hemorrhage-prone small-vessel disease pathology (cerebral amyloid angiopathy or hypertensive vasculopathy).Methods—Consecutive patients with cerebellar ICH from a single tertiary care medical center were recruite...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Marco Pasi, Sandro Marini, Andrea Morotti, Gregoire Boulouis, Li Xiong, Andreas Charidimou, Alison M. Ayres, Myung Joo Lee, Alessandro Biffi, Joshua N. Goldstein, Jonathan Rosand, M. Edip Gurol, Steven M. Greenberg, Anand Viswanathan Tags: Intracranial Hemorrhage Brief Reports Source Type: research
Intravenous Thrombolysis for Stroke and Presumed Stroke in Human Immunodeficiency Virus-Infected Adults Brief Report
Background and Purpose—Human immunodeficiency virus (HIV) infection has been shown to increase both ischemic and hemorrhagic stroke risks, but there are limited data on the safety and outcomes of intravenous thrombolysis with tPA (tissue-type plasminogen activator) for acute ischemic stroke in HIV-infected patients.Methods—A retrospective chart review of intravenous tPA-treated HIV patients who presented with acute stroke symptoms was performed in 7 large inner-city US academic centers (various search years between 2000 and 2017). We collected data on HIV, National Institutes of Health Stroke Scale score, ischemic stro...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Mahmoud A. AbdelRazek, Jose Gutierrez, David Mampre, Anna Cervantes–Arslanian, Cora Ormseth, Diogo Haussen, Kiran T. Thakur, Jennifer L. Lyons, Bryan R. Smith, Owen O’Connor, Joshua Z. Willey, Farrah J. Mateen Tags: Treatment, Complications, Mortality/Survival, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research
Statin Treatment in Patients With Intracerebral Hemorrhage Comments and Opinions
Source: Stroke - December 22, 2017 Category: Neurology Authors: Matthias Endres, Christian H. Nolte, Jan F. Scheitz Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Comments and Opinions Source Type: research
Nonpharmacological Management of Atrial Fibrillation in Patients at High Intracranial Hemorrhage Risk Topical Review
Source: Stroke - December 22, 2017 Category: Neurology Authors: M. Edip Gurol Tags: Atrial Fibrillation, Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research
Ambient Temperature and Stroke Risk Topical Review
Source: Stroke - December 22, 2017 Category: Neurology Authors: Pablo M. Lavados, Veronica V. Olavarria, Lorena Hoffmeister Tags: Mechanisms, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research
Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on expert opinion and small case series, with the efficacy of such treatments not well established. This document aims to provide an overview of sICH with a focus on pathophysiology and treatment.Methods—A literature review was performed for randomized trials, prospective and retrospective studies, opinion papers, case series, and case reports on the definitions, epidemiology, risk factors, pathophysiology, treatment, and outcome of sICH. The documen...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Shadi Yaghi, Joshua Z. Willey, Brett Cucchiara, Joshua N. Goldstein, Nicole R. Gonzales, Pooja Khatri, Louis J. Kim, Stephan A. Mayer, Kevin N. Sheth, Lee H. Schwamm Tags: Statements and Guidelines AHA/ASA Scientific Statement Source Type: research
Stroke: Highlights of Selected Articles Stroke: Highlights of Selected Articles
Source: Stroke - November 27, 2017 Category: Neurology Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Stroke: Highlights of Selected Articles Source Type: research
Prevalence and Natural History of Superficial Siderosis Clinical Sciences
This study aimed to report the prevalence and natural history of SS in a population-based study.Methods—Brain magnetic resonance imaging scans from the MCSA (Mayo Clinic Study of Aging), a population-based study of residents 50 to 89 years of age in Olmsted County, Minnesota, were reviewed. Participants with imaging consistent with SS were identified from 2011 through 2016. An inverse probability weighting approach was used to convert our observed frequencies to population prevalence of SS. Additional data abstracted included amyloid positron emission tomography, Apolipoprotein E genotype, coexisting cerebral microbleeds...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Michael Pichler, Prashanthi Vemuri, Alejandro A. Rabinstein, Jeremiah Aakre, Kelly D. Flemming, Robert D. Brown Jr, Neeraj Kumar, Kejal Kantarci, Walter Kremers, Michelle M. Mielke, David S. Knopman, Clifford R. Jack Jr, Ronald C. Petersen, Val Lowe, Jona Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors Clinical Sciences
Background and Purpose—Selective serotonin-reuptake inhibitors (SSRIs) impair platelet function and have been linked to a higher risk of spontaneous intracerebral hemorrhage—an association that may be augmented by oral anticoagulants (OAC). We aimed to assess whether preadmission treatment with SSRIs in patients with acute ischemic stroke is associated with post-thrombolysis symptomatic intracerebral hemorrhage (sICH) and functional outcome.Methods—A multicenter retrospective analysis was conducted in prospective registries of patients treated by thrombolysis within 4.5 hours of stroke onset. The association between ...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Jan F. Scheitz, Guillaume Turc, Linda Kuȷala, Alexandros A. Polymeris, Mirȷam R. Heldner, Thomas P. Zonneveld, Hebun Erdur, Sami Curtze, Christopher Traenka, Celine Breniere, Roland Wiest, Andrea Rocco, Gerli Sibolt, Henrik Gensicke, Matthia Tags: Complications, Ischemic Stroke Original Contributions Source Type: research
Statins and the Risk of Intracerebral Hemorrhage in Patients With Previous Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—Statin use was not associated with an increased risk of ICH among patients with a previous history of IS/TIA.
Source: Stroke - November 27, 2017 Category: Neurology Authors: David Gaist, Larry B. Goldstein, Lucia Cea Soriano, Luis Alberto Garcia Rodriguez Tags: Secondary Prevention, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Imaging Characteristics of Venous Parenchymal Abnormalities Clinical Sciences
Conclusions—Parenchymal lesions caused by CVT display specific anatomic patterns, which is mainly determined by the site of venous occlusion.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Audrey Arnoux, Aude Triquenot–Bagan, Daniela Andriuta, David Wallon, Evelyne Guegan–Massardier, Claire Leclercq, Olivier Martinaud, Melody Castier–Amouyel, Olivier Godefroy, Jean–Marc Bugnicourt Tags: Magnetic Resonance Imaging (MRI), Thrombosis Original Contributions Source Type: research
Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin Clinical Sciences
Conclusions—In anticoagulated patients with atrial fibrillation and risk factors for stroke, echocardiographic findings do not seem to add to the risk of thromboembolic events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Dragos Vinereanu, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G.M. de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander Tags: Arrhythmias, Echocardiography, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
