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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Contact Aspiration Versus Stent Retriever in Patients With Acute Ischemic Stroke With M2 Occlusion in the ASTER Randomized Trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization) Brief Report
Conclusions—First-line mechanical thrombectomy with CA compared with SR did not result in an increased successful revascularization rate in patients with acute stroke with isolated M2 occlusion.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Benjamin Gory, Bertrand Lapergue, Raphael Blanc, Julien Labreuche, Malek Ben Machaa, Alain Duhamel, Gautier Marnat, Suzana Saleme, Vincent Costalat, Serge Bracard, Hubert Desal, Mikael Mazighi, Arturo Consoli, Michel Piotin, for the ASTER Trial Investiga Tags: Revascularization, Stent, Treatment, Complications, Ischemic Stroke Brief Reports Source Type: research

Cerebrovascular Disease Knowledge Portal Topical Review
Source: Stroke - January 22, 2018 Category: Neurology Authors: Katherine M. Crawford, Cristina Gallego-Fabrega, Christina Kourkoulis, Laura Miyares, Sandro Marini, Jason Flannick, Noel P. Burtt, Marcin von Grotthuss, Benjamin Alexander, Maria C. Costanzo, Neil H. Vaishnav, Rainer Malik, Jennifer L. Hall, Michael Chon Tags: Genetic, Association Studies, Genetics, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research

Diagnosis of Cerebral Amyloid Angiopathy Topical Review
Source: Stroke - January 22, 2018 Category: Neurology Authors: Steven M. Greenberg, Andreas Charidimou Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage Topical Reviews Source Type: research

Stroke Incidence by Major Pathological Type and Ischemic Subtypes in the Auckland Regional Community Stroke Studies Clinical Sciences
Conclusions—A lack of change in IS and ICH incidence may reflect a trend toward increased incidence of younger strokes. Increased rates of large-artery atherosclerosis and small-vessel occlusion are associated with increased smoking and high blood pressure. Ethnic differences in the proportional distribution of pathological stroke subtypes suggest differential exposure and susceptibility to risk factors.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Rita V. Krishnamurthi, Suzanne Barker-Collo, Varsha Parag, Priyakumari Parmar, Emma Witt, Amy Jones, Susan Mahon, Craig S. Anderson, P. Alan Barber, Valery L. Feigin Tags: Epidemiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Letter by Chang et al Regarding Article, “Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial” Letter to the Editor
Source: Stroke - December 22, 2017 Category: Neurology Authors: Jason J. Chang, Nerses Sanossian, Georgios Tsivgoulis Tags: Biomarkers, Intracranial Hemorrhage, Neuroprotectants Letters to the Editor Source Type: research

Response by Fouda and Switzer to Letter Regarding Article, “Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial” Letter to the Editor
Source: Stroke - December 22, 2017 Category: Neurology Authors: Abdelrahman Y. Fouda, Jeffrey A. Switzer, MACH Investigators Tags: Intracranial Hemorrhage, Neuroprotectants Letters to the Editor Source Type: research

Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk Clinical Sciences
The objective of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of ICH.Methods—This prospective study included 96 110 participants of the Kailuan study, living in Kailuan community, Tangshan city, China, who were free of cardiovascular diseases and cancer at baseline (2006). Fasting blood glucose concentration was measured in 2006, 2008, 2010, and 2012. Updated cumulative average fasting blood glucose concentration was used as primary exposure of the current study. Incident ICH from 2006 to 2015 was confirmed by review of medical records.Results...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Intracranial Hemorrhage Original Contributions Source Type: research

Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture Clinical Sciences
Conclusions—Antihyperglycemic agent use rather than hyperglycemia is associated with decreased risk of aneurysmal subarachnoid hemorrhage, suggesting a possible protective effect of glucose-lowering agents in the pathogenesis of aneurysm rupture.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Anil Can, Victor M. Castro, Sheng Yu, Dmitriy Dligach, Sean Finan, Vivian S. Gainer, Nancy A. Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T. Weiss, Rose Du Tags: Risk Factors, Cerebral Aneurysm Original Contributions Source Type: research

Cognitive Impairment Before Intracerebral Hemorrhage Is Associated With Cerebral Amyloid Angiopathy Clinical Sciences
Conclusions—CAA (defined using magnetic resonance imaging markers) is associated with cognitive decline before symptomatic ICH. This provides evidence that small vessel disruption in CAA makes an independent contribution to cognitive impairment, in addition to effects due to brain injury caused directly by ICH.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02513316.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Gargi Banerȷee, Duncan Wilson, Gareth Ambler, Karen Osei–Bonsu Appiah, Clare Shakeshaft, Surabhika Lunawat, Hannah Cohen, Tarek Yousry Dr, Gregory Y.H. Lip, Keith W. Muir, Martin M. Brown, Rustam Al–Shahi Salman, Hans Rolf Jager, David Tags: Cerebrovascular Disease/Stroke, Cognitive Impairment, Intracranial Hemorrhage Original Contributions Source Type: research

Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Before this trial, the effectiveness of induced hypertension for DCI in aneurysmal subarachnoid hemorrhage patients was unknown because current literature consists only of uncontrolled case series. The results from our premature halted trial do not add any evidence to support induced hypertension and show that this treatment can lead to serious adverse events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01613235.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Celine S. Gathier, Walter M. van den Bergh, Mathieu van der Jagt, Bon H. Verweiȷ, Jan Willem Dankbaar, Marcella C. Muller, Annemarie W. Oldenbeuving, Gabriel J.E. Rinkel, Arȷen J.C. Slooter, for the HIMALAIA Study Group* Tags: Treatment, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Real-World Use of Apixaban for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Background and Purpose—The use of oral anticoagulant therapy for stroke prevention in atrial fibrillation has been transformed by the availability of the nonvitamin K antagonist oral anticoagulants. Real-world studies on the use of nonvitamin K antagonist oral anticoagulants would help elucidate their effectiveness and safety in daily clinical practice. Apixaban was the third nonvitamin K antagonist oral anticoagulants introduced to clinical practice, and increasing real-world studies have been published. Our aim was to summarize current evidence about real-world studies on apixaban for stroke prevention in atrial fibril...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Marco Proietti, Imma Romanazzi, Giulio Francesco Romiti, Alessio Farcomeni, Gregory Y.H. Lip Tags: Atrial Fibrillation, Anticoagulants, Quality and Outcomes Original Contributions Source Type: research

Transoceanic Management and Treatment of Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Our treatment strategy for aneurysmal subarachnoid hemorrhage resulted in a 30-day case fatality rate similar to those observed elsewhere, despite an 8-hour flight and a median treatment delay of 32 hours. This strategy therefore seems to be safe and reliable for isolated regions with small populations.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Mehdi Mejdoubi, Mathieu Schertz, Sylvia Zanolla, Hossein Mehdaoui, Michel Piotin Tags: Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research

Novel Telestroke Program Improves Thrombolysis for Acute Stroke Across 21 Hospitals of an Integrated Healthcare System Clinical Sciences
This study included 310 patients treated with alteplase in the pre–EXpediting the PRrocess of Evaluating and Stopping Stroke period and 557 patients treated with alteplase in the EXpediting the PRrocess of Evaluating and Stopping Stroke period. After implementation, alteplase administrations increased to 62/mo from 34/mo at baseline (P
Source: Stroke - December 22, 2017 Category: Neurology Authors: Mai N. Nguyen-Huynh, Jeffrey G. Klingman, Andrew L. Avins, Vivek A. Rao, Abigail Eaton, Sunil Bhopale, Anne C. Kim, John W. Morehouse, Alexander C. Flint Tags: Treatment, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

PROMIS GH (Patient-Reported Outcomes Measurement Information System Global Health) Scale in Stroke Clinical Sciences
The objective of this study was to evaluate the psychometric properties of PROMIS GH in patients with ischemic stroke and intracerebral hemorrhage.Methods—PROMIS GH and 6 PROMIS domain scales measuring same/similar constructs were electronically collected on 1102 patients with ischemic and hemorrhagic strokes at various stages of recovery from their stroke who were seen in a cerebrovascular clinic from October 12, 2015, through June 2, 2017. Confirmatory factor analysis was performed to evaluate the adequacy of 2-factor structure of component scores. Test–retest reliability and convergent validity of PROMIS GH items an...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Irene L. Katzan, Brittany Lapin Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat Basic Sciences
Conclusions—DHLA treatment improved neurofunction and alleviated inflammation through the lysosome-associated membrane protein-1/CaMKII/TAK1 pathway in early brain injury after SAH. DHLA may provide a promising treatment to alleviate early brain injury after SAH.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Keren Zhou, Budbazar Enkhjargal, Zhiyi Xie, Chengmei Sun, Lingyun Wu, Jay Malaguit, Sheng Chen, Jiping Tang, Jianmin Zhang, John H. Zhang Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Ischemia, Mechanisms Original Contributions Source Type: research