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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Letter by Yu et al Regarding Article, “Island Sign: An Imaging Predictor for Early Hematoma Expansion and Poor Outcome in Patients With Intracerebral Hemorrhage” Letter to the Editor
Source: Stroke - January 22, 2018 Category: Neurology Authors: Zhiyuan Yu, Jun Zheng, Chao You Tags: Intracranial Hemorrhage Letters to the Editor Source Type: research

Response by Li to Letter Regarding Article, “Island Sign: An Imaging Predictor for Early Hematoma Expansion and Poor Outcome in Patients With Intracerebral Hemorrhage” Letter to the Editor
Source: Stroke - January 22, 2018 Category: Neurology Authors: Qi Li Tags: Intracranial Hemorrhage Letters to the Editor Source Type: research

Letter by Liu et al Regarding Article, “Thrombolysis in Postoperative Stroke” Letter to the Editor
Source: Stroke - January 22, 2018 Category: Neurology Authors: Fujun Liu, Wei Chen, Jing Chen Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Letters to the Editor Source Type: research

Optimal Blood Pressure After Intracerebral Hemorrhage Editorial
Source: Stroke - January 22, 2018 Category: Neurology Authors: Alejandro A. Rabinstein Tags: Intracranial Hemorrhage Editorials Source Type: research

Stroke Incidence and Outcomes in Northeastern Greece Clinical Sciences
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Cerebrovascular Outcomes With Proton Pump Inhibitors and Thienopyridines Clinical Sciences
Background and Purpose—Pharmacokinetic and prior studies on thienopyridine and proton pump inhibitors (PPI) coadministration provide conflicting data for cardiovascular outcomes, whereas there is no established evidence on the association of concomitant use of PPI and thienopyridines with adverse cerebrovascular outcomes.Methods—We conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies from inception to July 2017, reporting following outcomes among patients treated with thienopyridine and PPI versus thienopyridine alone (1) ischemic stroke, (2) combined ischemic or hemorrhagi...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Konark Malhotra, Aristeidis H. Katsanos, Mohammad Bilal, Muhammad Fawad Ishfaq, Nitin Goyal, Georgios Tsivgoulis Tags: Meta Analysis, Ischemic Stroke Original Contributions Source Type: research

Retrospective Methods Analysis of Semiautomated Intracerebral Hemorrhage Volume Quantification From a Selection of the STICH II Cohort (Early Surgery Versus Initial Conservative Treatment in Patients With Spontaneous Supratentorial Lobar Intracerebral Haematomas) Clinical Sciences
Conclusions—Although the ABC/2 formula for calculating elliptical ICH is well validated, it must be used with caution in ICH scans where the elliptical shape of ICH is a false assumption. We validated the adjustment of the ABC/2.4 method in randomization, antithrombotic-associated, heterogeneous-density, and irregular-shape ICH.Clinical Trial Registration—URL: http://www.isrctn.com/ISRCTN22153967. Unique identifier: ISRCTN22153967.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Mark D. Haley, Barbara A. Gregson, W. Andrew Mould, Daniel F. Hanley, Alexander David Mendelow Tags: Computerized Tomography (CT), Intracranial Hemorrhage Original Contributions Source Type: research

Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—To identify predictors of in-hospital mortality in patients with aneurysmal subarachnoid hemorrhage and to estimate their impact.Methods—Retrospective analysis of prospective data from a nationwide multicenter registry on all aneurysmal subarachnoid hemorrhage cases admitted to a tertiary neurosurgical department in Switzerland (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]; 2009–2015). Both clinical and radiological independent predictors of in-hospital mortality were identified, and their effect size was determined by calculating adjusted odds ratios (aORs) using multivariate ...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Martin Nikolaus Stienen, Menno Germans, Jan–Karl Burkhardt, Marian C. Neidert, Christian Fung, David Bervini, Daniel Zumofen, Michel Rothlisberger, Serge Marbacher, Rodolfo Maduri, Thomas Robert, Martin A. Seule, Philippe Biȷlenga, Karl Schal Tags: Mortality/Survival, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Association Between Hyperacute Stage Blood Pressure Variability and Outcome in Patients With Spontaneous Intracerebral Hemorrhage Clinical Sciences
Conclusions—BPV during the hyperacute first minutes and hours after onset in patients with intracerebral hemorrhage was independently associated with poor functional outcome. Stabilization of BPV during this vulnerable period, in the pre-hospital and early emergency department course, is a potential therapeutic target for future clinical trials.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Pil-Wook Chung, Joon-Tae Kim, Nerses Sanossian, Sidney Starkmann, Scott Hamilton, Jeffrey Gornbein, Robin Conwit, Marc Eckstein, Frank Pratt, Sam Stratton, David S. Liebeskind, Jeffrey L. Saver Tags: High Blood Pressure, Intracranial Hemorrhage Original Contributions Source Type: research

Revised Framingham Stroke Risk Score, Nontraditional Risk Markers, and Incident Stroke in a Multiethnic Cohort Clinical Sciences
Conclusions—The R-FSRS downgraded stroke risk but had better calibration and discriminative ability for incident stroke compared with the original FSRS. Nontraditional risk markers modestly improved the discriminative ability of the R-FSRS, with coronary artery calcium performing the best.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah Tags: Epidemiology, Primary Prevention, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

STARTING-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis for Stroke Clinical Sciences
Background and Purpose—Symptomatic intracerebral hemorrhage (sICH) is a rare but the most feared complication of intravenous thrombolysis for ischemic stroke. We aimed to develop and validate a nomogram for individualized prediction of sICH in intravenous thrombolysis–treated stroke patients included in the multicenter SITS-ISTR (Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register).Methods—All patients registered in the SITS-ISTR by 179 Italian centers between May 2001 and March 2016 were originally included. The main outcome measure was sICH per the European Cooperative Acute Str...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Manuel Cappellari, Gianni Turcato, Stefano Forlivesi, Cecilia Zivelonghi, Paolo Bovi, Bruno Bonetti, Danilo Toni Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Carotid Atheroma From Men Has Significantly Higher Levels of Inflammation and Iron Metabolism Enabled by Macrophages Clinical Sciences
Conclusions—Male patients with carotid atheroma had more advanced and ruptured lesions associated with significantly higher levels of inflammatory macrophage infiltration and high iron stores in the blood and in their plaques. These findings help to understand sex differences and iron metabolism in atherosclerosis and factors related to atheroma progression.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Xi-Ming Yuan, Liam J. Ward, Claes Forssell, Nabeel Siraj, Wei Li Tags: Inflammation, Oxidant Stress, Pathophysiology, Proteomics, Atherosclerosis Original Contributions Source Type: research

Intracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis Basic Science
Conclusions—CoW regulatory regions link IA-associated SNPs to genes with a potential role in the development of IAs. Our data refine previous predictions on SNPs associated with IA and provide a substantial resource from which candidates for follow-up studies can be prioritized.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Melanie D. Laarman, Marit W. Vermunt, Rachel Kleinloog, Jelkȷe J. de Boer–Bergsma, Netherlands Brain Bank, Gabriel J.E. Rinkel, Menno P. Creyghton, Michal Mokry, Jeroen Bakkers, Ynte M. Ruigrok Tags: Computational Biology, Epigenetics, Gene Expression & Regulation, Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease Brief Report
Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals of mortality were calcu...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano, Hiroyasu Iso, Akiko Tamakoshi Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Detection of Anterior Circulation Large Artery Occlusion in Ischemic Stroke Using Noninvasive Cerebral Oximetry Brief Report
Background and Purpose—Large artery occlusion (LAO) in ischemic stroke requires recognition and triage to an endovascular stroke treatment center. Noninvasive LAO detection is needed to improve triage.Methods—Prospective study to test whether noninvasive cerebral oximetry can detect anterior circulation LAO in acute stroke. Interhemispheric ΔBrSO2 in LAO was compared with controls.Results—In LAO stroke, mean interhemispheric ΔBrSO2 was −8.3±5.8% (n=19), compared with 0.4±5.8% in small artery stroke (n=17), 0.4±6.0% in hemorrhagic stroke (n=14), and 0.2±7.5% in subjects without stroke (n=19) (P
Source: Stroke - January 22, 2018 Category: Neurology Authors: Alexander C. Flint, Shiv G. Bhandari, Sean P. Cullen, Adhikari V. Reddy, Daniel P. Hsu, Vivek A. Rao, Minal Patel, Jasmeen Pombra, Nancy J. Edwards, Sheila L. Chan Tags: Revascularization, Ischemic Stroke Brief Reports Source Type: research