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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Response by Parikh and Kamel to Letter Regarding Article, “Stroke Risk and Mortality in Patients With Ventricular Assist Devices” Letter to the Editor
Source: Stroke - December 22, 2016 Category: Neurology Authors: Neal S. Parikh, Hooman Kamel Tags: Heart Failure, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Letters to the Editor Source Type: research

Development and Validation of a Grading Scale for Primary Pontine Hemorrhage Clinical Sciences
Background and Purpose—We aimed to develop and validate a grading scale for predicting 30-day mortality and 90-day functional outcome in patients with primary pontine hemorrhage (PPH).Methods—We retrospectively reviewed records of consecutive patients with first-ever pontine hemorrhage from 3 teaching hospitals between 2005 and 2012. Independent factors associated with 30-day mortality were identified by logistic regression to establish a risk stratification scale, named the new PPH score. For validation of the new PPH score, we prospectively recruited subjects from 10 units between December 2014 and November 2015. The...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Kaibin Huang, Zhong Ji, Lihua Sun, Xiaoya Gao, Shaopeng Lin, Tao Liu, Shanfang Xie, Qishan Zhang, Wenchuan Xian, Saijun Zhou, Youquan Gu, Yongming Wu, Shengnan Wang, Zhenzhou Lin, Suyue Pan Tags: Clinical Studies, Prognosis, Quality and Outcomes, Intracranial Hemorrhage Original Contributions Source Type: research

Increased Stroke Burdens Among the Low-Income Young and Middle Aged in Rural China Clinical Sciences
Background and Purpose—Although stroke in the young and middle aged accounts for 31% of all strokes in China, the disease burden is unknown. We aimed to determine the secular trends in stroke incidence and the transition of subtypes in rural China over a 24-year period.Methods—In 1992, 14 920 residents were recruited to participate in the Tianjin Brain Study. Stroke events and all deaths were registered annually. We assessed the trends in incidence of first-ever stroke, including intracerebral hemorrhage and ischemic stroke, among adults aged 35 to 64 years during 1992 to 1999, 2000 to 2007, and 2008 to 2015. The ann...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Xianjia Ning, Jian Sun, Rongcai Jiang, Hongyan Lu, Lingling Bai, Min Shi, Jun Tu, Yanan Wu, Jinghua Wang, Jianning Zhang Tags: Epidemiology Original Contributions Source Type: research

Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Computed Tomographic Blend Sign Is Associated With Computed Tomographic Angiography Spot Sign and Predicts Secondary Neurological Deterioration After Intracerebral Hemorrhage Clinical Sciences
Conclusions—The BS, which is obtainable in noncontrast computed tomography, shows a high correlation with the computed tomographic angiography SS and is a reliable predictor of secondary neurological deterioration after spontaneous intracerebral hemorrhage.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Peter B. Sporns, Michael Schwake, Rene Schmidt, Andre Kemmling, Jens Minnerup, Wolfram Schwindt, Christian Cnyrim, Tarek Zoubi, Walter Heindel, Thomas Niederstadt, Uta Hanning Tags: Computerized Tomography (CT), Intracranial Hemorrhage Original Contributions Source Type: research

Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage) Clinical Sciences
Conclusions—EG-1962 was safe and tolerable to 800 mg, and in this, aneurysmal subarachnoid hemorrhage population was associated with reduced delayed cerebral ischemia and rescue therapy. Overall, the rate of favorable clinical outcome was greater in the EG-1962-treated group.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01893190.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Daniel Hanggi, Nima Etminan, Francois Aldrich, Hans Jakob Steiger, Stephan A. Mayer, Michael N. Diringer, Brian L. Hoh, J Mocco, Herbert J. Faleck, R. Loch Macdonald Tags: Clinical Studies, Intracranial Hemorrhage, Aneurysm Original Contributions Source Type: research

Anticoagulation Use and Clinical Outcomes After Major Bleeding on Dabigatran or Warfarin in Atrial Fibrillation Clinical Sciences
Conclusions—Dabigatran was associated with a superior benefit/risk ratio than warfarin and anticoagulation discontinuation in the treatment of atrial fibrillation patients who have survived a major bleed.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Inmaculada Hernandez, Yuting Zhang, Maria M. Brooks, Paul K.L. Chin, Samir Saba Tags: Atrial Fibrillation, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Long-Term Risk of Dementia Among Survivors of Ischemic or Hemorrhagic Stroke Clinical Sciences
Conclusions—Stroke increases dementia risk. Survivors of intracerebral hemorrhage and subarachnoid hemorrhage are at particularly high long-term risk of poststroke dementia.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Priscila Corraini, Victor W. Henderson, Anne G. Ording, Lars Pedersen, Erzsebet Horvath–Puho, Henrik T. Sorensen Tags: Epidemiology, Risk Factors, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage Basic Sciences
Background and Purpose—We assessed the elemental and biochemical effects of rehabilitation after intracerebral hemorrhage, with emphasis on iron-mediated oxidative stress, using a novel multimodal biospectroscopic imaging approach.Methods—Collagenase-induced striatal hemorrhage was produced in rats that were randomized to enriched rehabilitation or control intervention starting on day 7. Animals were euthanized on day 14 or 21, a period of ongoing cell death. We used biospectroscopic imaging techniques to precisely determine elemental and molecular changes on day 14. Hemoglobin content was assessed with resonance Raman...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Michael R. Williamson, Kristen Dietrich, Mark J. Hackett, Sally Caine, Colby A. Nadeau, Jasmine R. Aziz, Helen Nichol, Phyllis G. Paterson, Frederick Colbourne Tags: Basic Science Research, Mechanisms, Imaging, Intracranial Hemorrhage, Neuroprotectants Original Contributions Source Type: research

Perioperative Antihypertensive Treatment in Patients With Spontaneous Intracerebral Hemorrhage Brief Report
Conclusions—Perioperative intensive blood pressure lowering was not associated with a reduced incidence of rehemorrhage, death, or other serious adverse events.Clinical Trial Registration—URL: http://www.chictr.org.cn/. Unique identifier: ChiCTR-TRC-13004304.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Jun Zheng, Hao Li, Sen Lin, Junpeng Ma, Rui Guo, Lu Ma, Yuan Fang, Meng Tian, Ming Liu, Chao You Tags: High Blood Pressure, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Brief Reports Source Type: research

Magnetic Resonance Imaging and Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Topical Reviews
Source: Stroke - December 22, 2016 Category: Neurology Authors: Lisa A. van der Kleij, Jill B. De Vis, Jean-Marc Olivot, Lionel Calviere, Christophe Cognard, Nicolaas P.A. Zuithoff, Gabriel J.E. Rinkel, Jeroen Hendrikse, Mervyn D.I. Vergouwen Tags: Imaging, Magnetic Resonance Imaging (MRI), Meta Analysis, Cerebral Aneurysm, Cerebrovascular Disease/Stroke Topical Review Source Type: research

Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—Cerebral infarction after aneurysmal subarachnoid hemorrhage is a significant cause of substantial morbidity and mortality. Because early and delayed cerebral infarction after aneurysmal subarachnoid hemorrhage may be mediated by different processes, we evaluated whether aneurysm-securing methods contributed to infarcts and whether long-term outcomes differ between early and delayed infarcts.Methods—A post hoc analysis of the CONSCIOUS-1 study (Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage) was performed. Using multivariate logistic regressio...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Oliver G.S. Ayling, George M. Ibrahim, Naif M. Alotaibi, Peter A. Gooderham, R. Loch Macdonald Tags: Clinical Studies, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Intracranial Hemorrhage Original Contributions Source Type: research

Early Magnetic Resonance Imaging and Cognitive Markers of Hereditary Cerebral Amyloid Angiopathy Brief Report
Background and Purpose—Early markers for cerebral amyloid angiopathy are largely unknown. We aimed to identify which magnetic resonance imaging (MRI) (performed at 7 and 3T) and cognitive markers are an early sign in (pre) symptomatic subjects with hereditary cerebral hemorrhage with amyloidosis-Dutch type.Methods—Twenty-seven DNA-proven Dutch-type mutation carriers (15 symptomatic and 12 presymptomatic) (mean age of 45.9 years) and 33 controls (mean age of 45.6 years) were included. 7T and 3T MRI was performed, cerebral amyloid angiopathy and small-vessel disease type MRI markers were estimated, and cognitive performa...
Source: Stroke - November 27, 2016 Category: Neurology Authors: Sanneke van Rooden, Anna M. van Opstal, Gerda Labadie, Gisela M. Terwindt, Marieke J.H. Wermer, Andrew G. Webb, Huub A.M. Middelkoop, Steven M. Greenberg, Jeroen van der Grond, Mark A. van Buchem Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment Brief Reports Source Type: research

Acute Blood Pressure Management in Intracerebral Hemorrhage Emerging Therapy Critique
Source: Stroke - November 27, 2016 Category: Neurology Authors: Kenneth Butcher, Magdy Selim Tags: Intracranial Hemorrhage Emerging Therapy Critiques Source Type: research

Stroke: Highlights of Selected Articles Stroke: Highlights of Selected Articles
Source: Stroke - October 23, 2016 Category: Neurology Tags: Behavioral/Psychosocial Treatment, Cerebrovascular Procedures, Intracranial Hemorrhage, Ischemic Stroke, Neuroprotectants Stroke: Highlights of Selected Articles Source Type: research