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Source: Stroke
Condition: Hemorrhagic Stroke
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Total 995 results found since Jan 2013.
Classification of Bleeding Events Brief Report
Conclusions—Classification of ICH by ECASS III and HBC criteria show distinct differences. These differences warrant special attention during interpretation and comparison of scientific publications.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Ulf Neuberger, Markus Alfred Mohlenbruch, Christian Herweh, Christian Ulfert, Martin Bendszus, Johannes Pfaff Tags: Cerebrovascular Procedures, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research
Irregular Shape Identifies Ruptured Intracranial Aneurysm in Subarachnoid Hemorrhage Patients With Multiple Aneurysms Brief Report
Background and Purpose—We investigated which aneurysm-related risk factors for rupture best discriminate ruptured versus unruptured saccular intracranial aneurysms (sIAs) in subarachnoid hemorrhage patients with multiple sIAs.Methods—We included 264 subarachnoid hemorrhage patients with a ruptured sIA and at least one additional unruptured sIA, from the Kuopio Intracranial Aneurysm database from 2003 to 2015. These patients had 268 ruptured and 445 unruptured sIAs. Angiograms of the 713 sIAs were reevaluated for multiple variables describing aneurysm shape. Multivariate generalized linear mixed models were used to calc...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Joel Bȷorkman, Juhana Frosen, Olli Tahtinen, Daan Backes, Terhi Huttunen, Jaakko Harȷu, Jukka Huttunen, Mitȷa I. Kurki, Mikael von und zu Fraunberg, Timo Koivisto, Hannu Manninen, Juha E. Jaaskelainen, Antti E. Lindgren Tags: Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Brief Reports Source Type: research
Intensive Blood Pressure Lowering in Intracerebral Hemorrhage Controversies in Stroke
Source: Stroke - June 26, 2017 Category: Neurology Authors: Craig S. Anderson, Magdy H. Selim, Carlos A. Molina, Adnan I. Qureshi Tags: High Blood Pressure, Intracranial Hemorrhage Controversies in Stroke Source Type: research
Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke) Clinical Sciences
Conclusions—In patients treated with r-tPA, adjunctive argatroban was not associated with increased risk of symptomatic intracerebral hemorrhage and provides evidence that a definitive effectiveness trial is indicated.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique Identifier: NCT01464788.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Andrew D. Barreto, Gary A. Ford, Loren Shen, Claudia Pedroza, Jon Tyson, Chunyan Cai, Mohammad H. Rahbar, James C. Grotta, on behalf of the ARTSS-2 Investigators Tags: Clinical Studies, Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Original Contributions Source Type: research
To Treat or Not to Treat Clinical Sciences
Conclusions—Given the patient characteristics in this study, there is room for more patients to be treated with anticoagulants, without hemorrhages to prevail. In nonagenarians, hemorrhages increased somewhat more, but this did not affect the overall outcome in this age stratum.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Peter Appelros, Bahman Farahmand, Andreas Terent, Signild Asberg Tags: Arrhythmias, Secondary Prevention, Anticoagulants, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research
Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions—HBO induced activation of ATP/nicotinamide adenine dinucleotide/silent mating type information regulation 2 homolog 1 pathway and protected blood–brain barrier in hyperglycemic middle cerebral artery occlusion rats. HBO might be promising approach for treatment of acute ischemic stroke patients, especially patients with diabetes mellitus or treated with r-tPA (recombinant tissue-type plasminogen activator).
Source: Stroke - May 22, 2017 Category: Neurology Authors: Qin Hu, Anatol Manaenko, Hetao Bian, Zongduo Guo, Jun-Long Huang, Zhen-Ni Guo, Peng Yang, Jiping Tang, John H. Zhang Tags: Animal Models of Human Disease, Basic Science Research, Ischemia, Neuroprotectants Original Contributions Source Type: research
Prevalence of Imaging Biomarkers to Guide the Planning of Acute Stroke Reperfusion Trials Brief Report
Conclusions—As part of the feasibility analysis in stroke clinical trials, this analysis and the resulting tables can help investigators determine sample size and the number needed to screen.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Bin Jiang, Robyn L. Ball, Patrik Michel, Tudor Jovin, Manisha Desai, Ashraf Eskandari, Zack Naqvi, Max Wintermark Tags: Computerized Tomography (CT), Ischemic Stroke Brief Reports Source Type: research
Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke Brief Report
Conclusions—Our results demonstrate TLR4 involvement in hemorrhagic transformation induced by delayed tPA administration, very likely by increasing matrix metalloproteinase 9 expression.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Alicia Garcia–Culebras, Sara Palma–Tortosa, Ana Moraga, Isaac Garcia–Yebenes, Violeta Duran–Laforet, Maria I. Cuartero, Juan de la Parra, Ana L. Barrios–Munoz, Jaime Diaz–Guzman, Jesus M. Pradillo, Maria A. Moro, Ignaci Tags: Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research
Dietary Protein Intake and Stroke Risk in a General Japanese Population Clinical Sciences
Background and Purpose—The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein.Methods—A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary protein intake was estimated using a 70-item semiquantitative food frequency questionnaire. The risk estimates for incident stroke and its subtypes were calculated using a Cox proportional hazards model.Results—During the follow-up, 254 participants experienced stroke events; of these, 172 had ischemic str...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Mio Ozawa, Daigo Yoshida, Jun Hata, Tomoyuki Ohara, Naoko Mukai, Mao Shibata, Kazuhiro Uchida, Masashi Nagata, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya Tags: Diet and Nutrition, Epidemiology, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Hemorrhage Risk of Brain Arteriovenous Malformations During Pregnancy and Puerperium in a North American Cohort Clinical Sciences
Conclusions reached in existing literature about risk of arteriovenous malformation (AVM) hemorrhage during pregnancy are controversial. This study compares the risk of hemorrhage in pregnant and nonpregnant female patients with AVM in a North American cohort.Methods—We retrospectively reviewed female patients with AVM evaluated from 1990 to 2015. Exposure period for pregnancy and puerperium was calculated as 40 and 6 weeks, respectively, for each full-term pregnancy and 6 weeks for each abortion. Hemorrhage events and patient-years were calculated during an exposure period (pregnancy and puerperium), and a nonexposure p...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Jose L. Porras, Wuyang Yang, Eunice Philadelphia, Jody Law, Tomas Garzon-Muvdi, Justin M. Caplan, Geoffrey P. Colby, Alexander L. Coon, Rafael J. Tamargo, Judy Huang Tags: Pregnancy, Women, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Use of Noncontrast Computed Tomography and Computed Tomographic Perfusion in Predicting Intracerebral Hemorrhage After Intravenous Alteplase Therapy Clinical Sciences
Background and Purpose—Intracerebral hemorrhage is a feared complication of intravenous alteplase therapy in patients with acute ischemic stroke. We explore the use of multimodal computed tomography in predicting this complication.Methods—All patients were administered intravenous alteplase with/without intra-arterial therapy. An age- and sex-matched case–control design with classic and conditional logistic regression techniques was chosen for analyses. Outcome was parenchymal hemorrhage on 24- to 48-hour imaging. Exposure variables were imaging (noncontrast computed tomography hypoattenuation degree, relative volume...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Connor Batchelor, Pooneh Pordeli, Christopher D. d’Esterre, Mohamed Naȷm, Fahad S. Al–Aȷlan, Mari E. Boesen, Connor McDougall, Lisa Hur, Enrico Fainardi, Jai Jai Shiva Shankar, Marta Rubiera, Alexander V. Khaw, Michael D. Hill, Tags: Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Restarting Anticoagulant Therapy After Intracranial Hemorrhage Clinical Sciences
Background and Purpose—The safety and efficacy of restarting anticoagulation therapy after intracranial hemorrhage (ICH) remain unclear. We performed a systematic review and meta-analysis to summarize the associations of anticoagulation resumption with the subsequent risk of ICH recurrence and thromboembolism.Methods—We searched published medical literature to identify cohort studies involving adults with anticoagulation-associated ICH. Our predictor variable was resumption of anticoagulation. Outcome measures were thromboembolic events (stroke and myocardial infarction) and recurrence of ICH. After assessing study het...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Santosh B. Murthy, Ajay Gupta, Alexander E. Merkler, Babak B. Navi, Pitchaiah Mandava, Costantino Iadecola, Kevin N. Sheth, Daniel F. Hanley, Wendy C. Ziai, Hooman Kamel Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Myocardial Infarction, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Patient With Severe Moyamoya Disease Who Presents With Acute Cortical Blindness Illustrative Teaching Cases
Source: Stroke - April 24, 2017 Category: Neurology Authors: Aparna Sajja, Deki Tsering, Annie C. Mooser, Tiffani A. DeFreitas, Jessica Carpenter, Suresh N. Magge Tags: Revascularization, Intracranial Hemorrhage, Moyamoya, Transient Ischemic Attack (TIA) Illustrative Teaching Case Source Type: research
Risk of Stroke in Patients With Heart Failure Clinical Sciences
Conclusions—Heart failure was associated with increased short-term and long-term risk of all stroke subtypes, suggesting that heart failure is a potent and persistent risk factor for ischemic stroke, ICH, and SAH.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Kasper Adelborg, Szimonetta Szepligeti, Jens Sundboll, Erzsebet Horvath–Puho, Victor W. Henderson, Anne Ording, Lars Pedersen, Henrik Toft Sorensen Tags: Heart Failure, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Changes in the Employment Status and Risk of Stroke and Stroke Types Clinical Sciences
Conclusions—Job lost men and women and reemployed men had increased risks for both hemorrhagic and ischemic stroke incidence and mortality.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Ehab S. Eshak, Kaori Honjo, Hiroyasu Iso, Ai Ikeda, Manami Inoue, Norie Sawada, Shoichiro Tsugane Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
