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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate Brief Report
Conclusions—The CSF actively penetrates within the brain parenchyma in the gyrencephalic brain, as described for the glymphatic system in rodent. This parenchymal CSF circulation is severely impaired by SAH.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Romain Goulay, Julien Flament, Maxime Gauberti, Michael Naveau, Nolwenn Pasquet, Clement Gakuba, Evelyne Emery, Philippe Hantraye, Denis Vivien, Romina Aron-Badin, Thomas Gaberel Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies Brief Reports Source Type: research

Organizational Update Organizational Update
Source: Stroke - June 26, 2017 Category: Neurology Authors: Werner Hacke, Stephen Davis Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Organizational Updates Source Type: research

Response by de Ridder et al to Letter Regarding Article, “PAIS 2 (Paracetamol Acetaminophen in Stroke 2) Results of a Randomized, Double-Blind Placebo-Controlled Clinical Trial” Letter to the Editor
Source: Stroke - June 26, 2017 Category: Neurology Authors: Inger R. de Ridder, Diederik W.J. Dippel, H. Bart van der Worp Tags: Pharmacology, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Letters to the Editor Source Type: research

Letter by Hasan et al Regarding Article, “Aspirin and Risk of Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - June 26, 2017 Category: Neurology Authors: David M. Hasan, Emine Bayman, Joseph Broderick Tags: Aneurysm Letters to the Editor Source Type: research

Another Enchantment From ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) Editorial
Source: Stroke - June 26, 2017 Category: Neurology Authors: Peter D. Schellinger, Georgios Tsivgoulis Tags: Intracranial Hemorrhage, Ischemic Stroke Editorials Source Type: research

Daily Total Physical Activity and Incident Stroke Clinical Sciences
Conclusions—For Japanese people, moderate levels of total physical activity, particularly achieved by moderate-intensity activities, may be optimal for stroke prevention because excessive vigorous-intensity activities might not be beneficial or even disadvantageous for prevention of hemorrhagic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Yasuhiko Kubota, Hiroyasu Iso, Kazumasa Yamagishi, Norie Sawada, Shoichiro Tsugane Tags: Epidemiology, Exercise, Primary Prevention, Race and Ethnicity, Risk Factors Original Contributions Source Type: research

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults Clinical Sciences
Conclusions—Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Annette Aigner, Ulrike Grittner, Arndt Rolfs, Bo Norrving, Bob Siegerink, Markus A. Busch Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Psychiatric Hospitalization Increases Short-Term Risk of Stroke Clinical Sciences
Conclusions—Psychiatric hospitalization increases the short-term risk of stroke, particularly within the 15-day period after hospitalization.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jonah P. Zuflacht, Yuefan Shao, Ian M. Kronish, Donald Edmondson, Mitchell S.V. Elkind, Hooman Kamel, Amelia K. Boehme, Joshua Z. Willey Tags: Epidemiology, Risk Factors, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Association Between Previous Use of Antiplatelet Therapy and Intracerebral Hemorrhage Outcomes Clinical Sciences
Conclusions—Our study suggests that among patients with ICH, previous use of CAPT, but not SAPT, was associated with higher risk for in-hospital mortality.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Nadeem I. Khan, Fazeel M. Siddiqui, Joshua N. Goldstein, Margueritte Cox, Ying Xian, Roland A. Matsouaka, Paul A. Heidenreich, Eric D. Peterson, Deepak L. Bhatt, Gregg C. Fonarow, Lee H. Schwamm, Eric E. Smith Tags: Mortality/Survival, Intracranial Hemorrhage Original Contributions Source Type: research

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis Clinical Sciences
Background and Purpose—Significance and management of blood pressure (BP) changes in acute stroke care are unclear. Here, we aimed to investigate the impact of 24-hour BP variability (BPV) on outcome in patients with acute ischemic stroke treated with intravenous thrombolysis.Methods—From the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis registry, 28 976 patients with documented pre-treatment systolic BP at 2 and 24 hours were analyzed. The primary measure of BP variability was successive variability. Data were preprocessed using coarsened exact matching. We assessed early neurological ...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Lars Kellert, Christian Hametner, Niaz Ahmed, Geraldine Rauch, Mary J. MacLeod, Francesco Perini, Kennedy R. Lees, Peter A. Ringleb Tags: Ischemic Stroke Original Contributions Source Type: research

Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands) Clinical Sciences
Conclusions—BP does not affect the benefit or safety of IAT in patients with acute ischemic stroke caused by proximal intracranial vessel occlusion. Our data provide no arguments to withhold or delay IAT based on BP.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Maxim J.H.L. Mulder, Saliha Ergezen, Hester F. Lingsma, Olvert A. Berkhemer, Puck S.S. Fransen, Debbie Beumer, Lucie A. van den Berg, Geert Lycklama a Niȷeholt, Bart J. Emmer, H. Bart van der Worp, Paul J. Nederkoorn, Yvo B.W.E.M. Roos, Robert J. v Tags: High Blood Pressure, Revascularization, Stent, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Original Contributions Source Type: research

Low- Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy Clinical Sciences
Conclusions—Low-dose alteplase may improve outcomes in thrombolysis-treated acute ischemic stroke patients on prior APT, but this requires further evaluation in a randomized controlled trial.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01422616.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Thompson G. Robinson, Xia Wang, Hisatomi Arima, Philip M. Bath, Laurent Billot, Joseph P. Broderick, Andrew M. Demchuk, Geoffery A. Donnan, Jong S. Kim, Pablo M. Lavados, Tsong-Hai Lee, Richard I. Lindley, Sheila C. O. Martins, Veronica V. Olavarria, Jeya Tags: Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Paramedic Initiation of Neuroprotective Agent Infusions Clinical Sciences
Conclusions—Paramedic infusion initiation using gravity-controlled tubing permits rapid achievement of target serum levels of potential neuroprotective agents. The absence of association of clinical outcomes with achieved magnesium levels provides further evidence that magnesium is not biologically neuroprotective in acute stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Kristina Shkirkova, Sidney Starkman, Nerses Sanossian, Marc Eckstein, Samuel Stratton, Frank Pratt, Robin Conwit, Scott Hamilton, Latisha Sharma, David Liebeskind, Lucas Restrepo, Miguel Valdes-Sueiras, Jeffrey L. Saver Tags: Cerebrovascular Disease/Stroke, Neuroprotectants Original Contributions Source Type: research

Exacerbation of Thromboinflammation by Hyperglycemia Precipitates Cerebral Infarct Growth and Hemorrhagic Transformation Basic Sciences
Conclusions—We show that hyperglycemia primes the thromboinflammatory cascade, thus, amplifying middle cerebral artery occlusion–induced DMT. DMT exacerbation in hyperglycemic rats impaired reperfusion and precipitated neurovascular damage, blood–brain barrier disruption, and hemorrhagic transformation. Our results designate DMT as a possible target for reduction of the deleterious impact of hyperglycemia in acute ischemic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Varouna Syvannarath, Veronique Ollivier, Clement Journe, Sandrine Delbosc, Celina Ducroux, William Boisseau, Liliane Louedec, Lucas Di Meglio, Stephane Loyau, Martine Jandrot–Perrus, Louis Potier, Jean–Baptiste Mi Tags: Biomarkers, Inflammation, Pathophysiology, Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research

Migraine and Cerebrovascular Atherosclerosis in Patients With Ischemic Stroke Brief Report
Conclusions—Migraine is not associated with excess atherosclerosis in large vessels in patients with acute ischemic stroke. Our findings suggest that the biological mechanisms by which migraine results in ischemic stroke are not related to macrovascular cerebral atherosclerosis.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Hendrikus J.A. van Os, Inge A. Mulder, Alexander Broersen, Ale Algra, Irene C. van der Schaaf, L. Jaap Kappelle, Birgitta K. Velthuis, Gisela M. Terwindt, Wouter J. Schonewille, Marieke C. Visser, Michel D. Ferrari, Marianne A.A. van Walderveen, Marieke J Tags: Computerized Tomography (CT), Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Atherosclerosis Brief Reports Source Type: research