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Source: Stroke
Condition: Hemorrhagic Stroke
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Total 995 results found since Jan 2013.
Cost-Effectiveness of Thrombectomy in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—Based on randomized trial data, this study demonstrates that IVMT used to treat acute ischemic stroke is cost-effective when compared with IVT alone.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01062698.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Hamza Achit, Marc Soudant, Kossar Hosseini, Aurelie Bannay, Jonathan Epstein, Serge Bracard, Francis Guillemin Tags: Cost-Effectiveness, Ischemic Stroke Original Contributions Source Type: research
Normobaric Hyperoxia Reduces Blood Occludin Fragments in Rats and Patients With Acute Ischemic Stroke Basic Sciences
Conclusions—Blood occludin may be a clinically viable biomarker for evaluating BBB damage during ischemia/reperfusion. NBO therapy has the potential to reduce blood occludin, protect BBB, and improve outcome in AIS patients with intravenous tPA thrombolysis.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02974283.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Shuhai Shi, Zhifeng Qi, Qingfeng Ma, Rong Pan, Graham S. Timmins, Yongmei Zhao, Wenjuan Shi, Yunzhou Zhang, Xunming Ji, Ke Jian Liu Tags: Biomarkers, Clinical Studies, Translational Studies, Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research
Hemorrhagic Transformation After Large Cerebral Infarction in Rats Pretreated With Dabigatran or Warfarin Basic Sciences
Background and Purpose—It is uncertain whether hemorrhagic transformation (HT) after large cerebral infarction is less frequent in dabigatran users than warfarin users. We compared the occurrence of HT after large cerebral infarction among rats pretreated with dabigatran, warfarin, or placebo.Methods—This was a triple-blind, randomized, and placebo-controlled experiment. After treatment with warfarin (0.2 mg/kg), dabigatran (20 mg/kg), or saline for 7 days, Wistar rats were subjected to transient middle cerebral artery occlusion. As the primary outcome, HT was determined by gradient-recalled echo imaging. For the secon...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Il Kwon, Sunho An, Jayoung Kim, Seung-Hee Yang, Joonsang Yoo, Jang-Hyun Baek, Hyo Suk Nam, Young Dae Kim, Hye Sun Lee, Hyun-Jung Choi, Ji Hoe Heo Tags: Magnetic Resonance Imaging (MRI), Anticoagulants, Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages Brief Report
Conclusions—Shorter mean transit time through the AVM nidus, lower DV TTP/FA TTP, and the high prevalence of venous varices suggests that high flow is an important feature of unruptured bAVMs with hemosiderin.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Xiaolin Chen, Daniel L. Cooke, David Saloner, Jeffrey Nelson, Hua Su, Michael T. Lawton, Christopher Hess, Tarik Tihan, Yuanli Zhao, Helen Kim Tags: Clinical Studies, Hemodynamics, Imaging, Cerebrovascular Malformations, Vascular Disease Brief Reports Source Type: research
Minocycline in Acute Cerebral Hemorrhage Brief Report
Conclusions—In intracerebral hemorrhage, a 400 mg dose of minocycline was safe and achieved neuroprotective serum concentrations. However, oral administration led to delayed absorption in these critically ill patients and should not be used when rapid, high concentrations are desired. Given the safety and pharmacokinetic profile of minocycline in intracerebral hemorrhage and promising data in the treatment of ischemic stroke, intravenous minocycline is an excellent candidate for a prehospital treatment trial.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01805895.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Abdelrahman Y. Fouda, Andrea S. Newsome, Samantha Spellicy, Jennifer L. Waller, Wenbo Zhi, David C. Hess, Adviye Ergul, David J. Edwards, Susan C. Fagan, Jeffrey A. Switzer Tags: Intracranial Hemorrhage, Neuroprotectants Brief Reports Source Type: research
White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke Brief Report
Conclusions—Mechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Kunakorn Atchaneeyasakul, Thabele Leslie-Mazwi, Kathleen Donahue, Anne-Katrin Giese, Natalia S. Rost Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research
Antithrombotic Treatment After Stroke Because Of Intracerebral Hemorrhage Cochrane Corner
Source: Stroke - August 28, 2017 Category: Neurology Authors: Luke A. Perry, Eivind Berge, Joshua Bowditch, Elisabeth Forfang, Ole Morten Ronning, Graeme J. Hankey, Elmer Villanueva, Rustam Al–Shahi Salman Tags: Secondary Prevention, Meta Analysis, Intracranial Hemorrhage Cochrane Corner Source Type: research
Letter by Barco et al Regarding Article, “Restarting Anticoagulant Therapy After Intracranial Hemorrhage: A Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - August 28, 2017 Category: Neurology Authors: Stefano Barco, Frederikus A. Klok, Francesco Dentali Tags: Embolism Letters to the Editor Source Type: research
Response by Murthy et al to Letter Regarding Article, “Restarting Anticoagulant Therapy After Intracranial Hemorrhage: A Systematic Review and Meta-Analysis” Letter to the Editor
Source: Stroke - August 28, 2017 Category: Neurology Authors: Santosh B. Murthy, Ajay Gupta, Hooman Kamel Tags: Atrial Fibrillation, Intracranial Hemorrhage, Ischemic Stroke Letters to the Editor Source Type: research
Correction to: Role of Periostin in Early Brain Injury After Subarachnoid Hemorrhage in Mice Correction
Source: Stroke - August 28, 2017 Category: Neurology Tags: Corrections Source Type: research
Towards Improved Translational Stroke Research Editorial
Source: Stroke - August 28, 2017 Category: Neurology Authors: Charlotte Zerna, Michael D. Hill, Johannes Boltze Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Editorials Source Type: research
Readmission After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—In this national analysis, readmission was primarily attributable to new medical complications in patients with greater comorbidities and severity of SAH rather than exacerbation of complications from the SAH hospitalization. Additionally, hospital readmission rates did not correlate with other established quality metrics. Therefore, readmission may be a suboptimal quality indicator in the SAH population.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Hormuzdiyar H. Dasenbrock, Frederico Angriman, Timothy R. Smith, William B. Gormley, Kai U. Frerichs, M. Ali Aziz-Sultan, Rose Du Tags: Complications, Mortality/Survival, Quality and Outcomes, Cerebral Aneurysm Original Contributions Source Type: research
MicroRNA Changes in Cerebrospinal Fluid After Subarachnoid Hemorrhage Clinical Sciences
This study compared miRNA profiles in cerebrospinal fluid from neurologically healthy patients, as well as SAH patients with and without subsequent development of DCI.Methods—In a prospective case–control study of SAH patients treated with external ventricular drainage and neurologically healthy patients, miRNA profiles in cerebrospinal fluid were screened and validated using 2 different high-throughput real-time quantification polymerase chain reaction techniques. The occurrence of DCI was documented in patient charts and subsequently reviewed independently by 2 physicians.Results—MiRNA profiles from 27 SAH patients...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Soren Bache, Rune Rasmussen, Maria Rossing, Finn Pedersen Laigaard, Finn Cilius Nielsen, Kirsten Moller Tags: Clinical Studies, Pathophysiology, Epigenetics, Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research
Risk Factors of Sudden Death From Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—One in every 4 subarachnoid hemorrhage (SAH) patients dies suddenly outside hospital, but most SAH risk factor studies focus on hospitalized patients. We studied the differences in risk factors between hospitalized SAH and sudden-death SAH patients.Methods—The population-based FINRISK study cohort of 65 521 individuals was followed up for 1.52 million person-years. The Cox proportional hazards model calculated hazard ratios (HRs), with all analyses adjusted for known SAH risk factors, marital status, and socioeconomic status. A competing risks model analyzed differences in risk factors between ...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Joni Valdemar Lindbohm, Jaakko Kaprio, Pekka Jousilahti, Veikko Salomaa, Miikka Korja Tags: Epidemiology, Risk Factors, Intracranial Hemorrhage, Aneurysm Original Contributions Source Type: research
Permeability Surface of Deep Middle Cerebral Artery Territory on Computed Tomographic Perfusion Predicts Hemorrhagic Transformation After Stroke Clinical Sciences
Conclusions—Increased PS can predict HT of deep MCA territory after recanalization therapy for cerebral proximal large-vessel occlusion. Proximal MCA-M1 complete occlusion and distal internal carotid artery occlusion in conjunction with poor collaterals elevate deep MCA territory PS.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Qiao Li, Xinyi Gao, Zhenwei Yao, Xiaoyuan Feng, Huijin He, Jing Xue, Peiyi Gao, Lumeng Yang, Xin Cheng, Weijian Chen, Yunjun Yang Tags: Angiography, Computerized Tomography (CT), Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research
