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Outcomes of intravenous tissue plasminogen activator for acute ischaemic stroke in HIV‐infected adults
ConclusionsThe in‐hospital mortality is higher amongst HIV‐infected AIS patients than HIV‐uninfected patients. However, the risk of death amongst HIV‐infected patients treated with IV‐TPA is similar to HIV‐uninfected groups.
Source: European Journal of Neurology - July 10, 2014 Category: Neurology Authors: E. M. Sweeney, K. T. Thakur, J. L. Lyons, B. R. Smith, J. Z. Willey, A. M. Cervantes‐Arslanian, M. K. Hickey, K. Uchino, D. C. Haussen, S. Koch, L. H. Schwamm, M. S. V. Elkind, R. T. Shinohara, F. J. Mateen Tags: Original Article Source Type: research

Dehydration is an independent predictor of discharge outcome and admission cost in acute ischaemic stroke
ConclusionAdmission dehydration is associated with worse discharge outcomes and higher admission costs in acute ischaemic stroke but not in hemorrhagic stroke.
Source: European Journal of Neurology - April 30, 2014 Category: Neurology Authors: C.‐H. Liu, S.‐C. Lin, J.‐R. Lin, J.‐T. Yang, Y.‐J. Chang, C.‐H. Chang, T.‐Y. Chang, K.‐L. Huang, S.‐J. Ryu, T.‐H. Lee Tags: Original Article Source Type: research

Periodontal disease and stroke: a meta‐analysis of cohort studies
This review aimed to determine the association between periodontal disease and stroke incidence by a meta‐analysis of cohort studies. Cohort studies that evaluated the incidence of stroke (fatal or non‐fatal, ischaemic or haemorrhagic) and baseline periodontal status and calculated relative risk values were included. The quality of the included studies was assessed using an evaluation grid. The analyses were conducted separately for three outcomes: periodontitis, gingivitis and loss of teeth. Adjusted values of relative risk or of hazard ratio were used to assess risk values in each study. Random effects meta‐analyse...
Source: European Journal of Neurology - April 1, 2014 Category: Neurology Authors: A. Lafon, B. Pereira, T. Dufour, V. Rigouby, M. Giroud, Y. Béjot, S. Tubert‐Jeannin Tags: Review Article Source Type: research

B‐type natriuretic peptide predicts stroke of presumable cardioembolic origin in addition to coronary artery calcification
ConclusionsBNP predicts presumable cardioembolic stroke independent of coronary calcification.
Source: European Journal of Neurology - March 24, 2014 Category: Neurology Authors: K. Kara, J. Gronewold, T. Neumann, A. A. Mahabadi, C. Weimar, N. Lehmann, K. Berger, H. I. M. Kälsch, M. Bauer, M. Broecker‐Preuss, S. Möhlenkamp, S. Moebus, K.‐H. Jöckel, R. Erbel, D. M. Hermann Tags: Original Article Source Type: research

Comparison of stent retriever and intra‐arterial fibrinolysis in patients with acute ischaemic stroke
ConclusionsStent retriever was as safe as and more effective than IAF. Our findings suggest that SR may be considered as an initial modality rather than IAF in acute stroke patients who undergo endovascular treatment.
Source: European Journal of Neurology - February 24, 2014 Category: Neurology Authors: D. Song, B. M. Kim, D. J. Kim, Y. D. Kim, J. Kim, H. S. Lee, H. S. Nam, J. H. Heo Tags: Original Article Source Type: research

Intracranial artery dissection
The aim of this narrative review is to evaluate the pathogenesis, clinical features, diagnosis, treatment and prognosis of intracranial artery dissection (IAD). IAD is a rare and often unrecognized cause of stroke or subarachnoid haemorrhage (SAH), especially in young adults. Two types of IAD can be identified: a subintimal or subadventitial dissection. It is suggested that a subintimal dissection results in luminal stenosis, thromboembolism and subsequently cerebral ischaemia, whilst a subadventitial IAD could result in the formation of a pseudo‐aneurysm and compression on brainstem or cranial nerves. Rupture of such a ...
Source: European Journal of Neurology - February 23, 2014 Category: Neurology Authors: T. Sikkema, M. Uyttenboogaart, O. Eshghi, J. De Keyser, R. Brouns, J. M. C. Dijk, G. J. Luijckx Tags: Review Article Source Type: research

Effects of emergency medical service transport on acute stroke care
ConclusionsPatient transport with EMS was independently associated with faster hospital arrival and shorter time periods from hospital admission to brain imaging and to the frequency of thrombolysis.
Source: European Journal of Neurology - January 28, 2014 Category: Neurology Authors: J. Minnerup, H. Wersching, M. Unrath, K. Berger Tags: Short Communication Source Type: research

Higher baseline international normalized ratio value correlates with higher mortality in intracerebral hemorrhage during warfarin use
ConclusionsPatients with OAC‐associated ICH had more severe strokes and higher mortality compared with patients with ICH not related to OAC. Higher baseline INR was associated with increased 3‐month mortality.
Source: European Journal of Neurology - January 21, 2014 Category: Neurology Authors: S. Curtze, D. Strbian, A. Meretoja, J. Putaala, H. Eriksson, E. Haapaniemi, S. Mustanoja, T. Sairanen, J. Satopää, H. Silvennoinen, M. Niemelä, M. Kaste, T. Tatlisumak Tags: Original Article Source Type: research

Dysarthria plus dysphagia is associated with severe sleep‐disordered breathing in patients with acute intracerebral hemorrhage
ConclusionMost Japanese patients with acute ICH had SDB, and dysarthria plus dysphagia was associated with severe SDB.
Source: European Journal of Neurology - December 7, 2013 Category: Neurology Authors: K. Shibazaki, K. Kimura, J. Aoki, J. Uemura, S. Fujii, K. Sakai Tags: Original Article Source Type: research

Effects of low estimated glomerular filtration rate on outcomes after stroke: a hospital‐based stroke registry in China
ConclusionsThere were no appreciable effects of low eGFR on death/disability at 90 days independent of other prognostic factors in Chinese patients with acute stroke.
Source: European Journal of Neurology - November 22, 2013 Category: Neurology Authors: J. Yang, H. Arima, J. Zhou, Y. Zhao, Q. Li, G. Wu, Y. Zhang Tags: Short Communication Source Type: research

Intravenous thrombolysis for patients with reverse magnetic resonance angiography and diffusion‐weighted imaging mismatch: SAMURAI and NCVC rt‐PA Registries
ConclusionRMM was observed in 5% of patients treated with rt‐PA and associated with cardioembolism. Patients with RMM may benefit from thrombolysis compared with those with EIC with MAO, although increment in the rate of sICH is a concern.
Source: European Journal of Neurology - November 22, 2013 Category: Neurology Authors: Y. Sakamoto, M. Koga, K. Kimura, K. Nagatsuka, S. Okuda, K. Kario, Y. Hasegawa, Y. Okada, H. Yamagami, E. Furui, J. Nakagawara, Y. Shiokawa, T. Okata, J. Kobayashi, E. Tanaka, K. Minematsu, K. Toyoda Tags: Original Article Source Type: research

Lost potential of kidney and liver donors amongst deceased intracerebral hemorrhage patients
ConclusionsA considerable number of ICH patients are potential organ donors if the evaluation takes place on arrival and organ donation is considered as part of usual end‐of‐life care.
Source: European Journal of Neurology - November 7, 2013 Category: Neurology Authors: T. Sairanen, A. Koivisto, A.‐M. Koivusalo, K. Rantanen, S. Mustanoja, A. Meretoja, J. Putaala, D. Strbian, M. Kaste, H. Isoniemi, T. Tatlisumak Tags: Original Article Source Type: research

Benefit of thrombolysis for stroke is maintained around the clock: results from the SITS‐EAST Registry
ConclusionsThe time when stroke occurs (day versus evening versus night) does not affect the outcome after thrombolysis despite the fact that patients with night‐time strokes have worse time management.
Source: European Journal of Neurology - September 16, 2013 Category: Neurology Authors: J. Kõrv, R. Vibo, P. Kadlecová, A. Kobayashi, A. Czlonkowska, M. Brozman, V. Švigelj, L. Csiba, K. Fekete, V. Demarin, A. Vilionskis, D. Jatuzis, Y. Krespi, N. Ahmed, R. Mikulík, Tags: Original Article Source Type: research

Prevalence of atrial fibrillation in intracerebral hemorrhage
ConclusionsAtrial fibrillation is a frequent comorbidity in patients suffering an ICH. Our findings underline the prevailing uncertainty regarding the anticoagulation management of AF after ICH.
Source: European Journal of Neurology - June 12, 2013 Category: Neurology Authors: S. Horstmann, T. Rizos, E. Jenetzky, C. Gumbinger, W. Hacke, R. Veltkamp Tags: Original Article Source Type: research

Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors
ConclusionsIn young ischaemic stroke patients, the magnitude of seizure risk and the major risk factors were similar to older ischaemic stroke patients but risk factors for ASSs and LPSs differed.
Source: European Journal of Neurology - April 14, 2013 Category: Neurology Authors: R. Roivainen, E. Haapaniemi, J. Putaala, M. Kaste, T. Tatlisumak Tags: Original Article Source Type: research

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