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Risk of stroke following antivenom use after venomous snakebite: correspondence
We read with great interest the epidemiological study by Hunget al.1 on the risk of stroke with antivenom use after venomous snakebite in Taiwan. According to the national medical claims data, the authors provide us with useful information and disclose that venomous snakebite is associated with an increased risk of hemorrhagic stroke after the use of antivenom after using the matching propensity score in relevant measurable covariates. We strongly agree with the comments by Yehet al.2 on the unmeasured confounders associated with stroke in the present study. Furthermore, we are concerned that other residual confounders rel...
Source: QJM - April 26, 2023 Category: Internal Medicine Source Type: research

Current Applications of Susceptibility Weighted Images in Pediatric Neurological Diseases
ConclusionIts high susceptibility for blood products, iron depositions, and calcifications makes susceptibility-weighted imaging an important additional sequence for the diagnostic workup of pediatric brain pathologic abnormalities that should be routinely added in our department. Compared with conventional MRI sequences, susceptibility-weighted imaging may show lesions with better detail and higher sensitivity. Familiarity with the pediatric susceptibility-weighted imaging signal variance is essential to prevent misdiagnosis.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Post Stroke Hyperglycemia as a marker of Stroke Severity and Prognosis: A cohort study
ConclusionFrom our study we can conclude that diabetes mellitus as a risk factor in cases of stroke leads to increase complications and worsens the outcome in cases of stroke whether hemorrhagic or ischemic.RecommendationsFrom our study we recommended strict control of diabetes mellitus when present in cases of stroke to avoid bad outcome and to prevent complications in these cases.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Septic cerebral emboli as a risk factor for thrombolysis-related haemorrhagic transformation
For the sake of completeness the risk factors enumerated by Wanget al. for haemorrhagic transformation of acute cerebral infarcts after intravenous thrombolysis (IVT)1 ought to include infective endocarditis (IE)-related septic emboli.2 In the latter study, which covered the period 2002 –10, 222 patients (mean age 69; 46% female) were identified who were treated with IVT for acute ischaemic stroke associated with IE. These patients were compared with 134 048 counterparts (mean age 69; 49% female) treated with IVT in the absence of IE. The rate of IVT-related intracerebral haemorr hage was significantly (P = 0.006) hi...
Source: QJM - January 25, 2019 Category: Internal Medicine Source Type: research

Reply: Septic cerebral emboli as a risk factor for thrombolysis-related haemorrhagic transformation
We appreciate the opportunity to respond to Dr. Jolobe ’s letter titled ‘Septic cerebral emboli as a risk factor for thrombolysis-related hemorrhagic transformation’. Dr. Jolobe made a nice comment on our article titled ‘Risk factors of hemorrhagic transformation after intravenous thrombolysis with rt-PA in acute cerebral infarction’.1 We agree that septic cerebral emboli was a risk factor for thrombolysis-related hemorrhagic transformation as demonstrated in an early study.2 In fact, it was based on this early study and the following studies that intravenous thrombolysis is not recommended for patients with acut...
Source: QJM - January 25, 2019 Category: Internal Medicine Source Type: research

Epidemiology, risk factors and characteristics of pediatric stroke: a nationwide population-based study
Conclusions and implicationsInfants younger than 2  years, boys and children in lower socioeconomic status have a significantly higher risk of stroke. Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke. More than half of the children with stroke had underlying diseases and the causes of hemorrhagic stroke are signifi cantly different from ischemic stroke.
Source: QJM - April 10, 2018 Category: Internal Medicine Source Type: research

The potential impact of sleep-related movement disorders on stroke risk: a population-based longitudinal study
ConclusionsPatients with SRMD were found to have an increased risk of all-cause stroke along with a higher possibility of hemorrhagic stroke over ischemic stroke.
Source: QJM - May 8, 2017 Category: Internal Medicine Source Type: research

Underuse of screening in Osler –Weber–Rendu syndrome
<span class="paragraphSection">According to the view expressed by the authors the management of Hereditary Haemorrhagic Telangiectasia (HHT) should include prevention of complications of vascular lesions.<a href="#hcw221-B1" class="reflinks">¹</a> Accordingly, the opportunity should have been taken to screen the patient for pulmonary arteriovenous malformations (PAVM), the latter a feature in 15 –50% of patients with HHT.<a href="#hcw221-B2" class="reflinks">²</a> With transthoracic contrast echocardiography as the imaging modality, the Internati...
Source: QJM - January 12, 2017 Category: Internal Medicine Source Type: research

The causes of hypopituitarism in the absence of abnormal pituitary imaging
Conclusion: These results show that hypopituitarism in the absence of pituitary pathology or an identifiable cause is rare. In patients with multiple anterior pituitary hormone deficiencies haemochromatosis and sarcoidosis should be considered.
Source: QJM - December 20, 2013 Category: Internal Medicine Authors: Wilson, V., Mallipedhi, A., Stephens, J. W., Redfern, R. M., Price, D. E. Tags: Original papers Source Type: research