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Source: Translational Stroke Research
Condition: Hemorrhagic Stroke
Drug: Metformin
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Metformin Alleviates Delayed Hydrocephalus after Intraventricular Hemorrhage by Inhibiting Inflammation and Fibrosis
In conclusion, metformin attenuated neuroinflammation and subsequent fibrosis after IVH by regulating AMPK /SIRT1/ NF-κB pathways, thereby reducing delayed hydrocephalus. Metformin may be a promising therapeutic agent to prevent delayed hydrocephalus following IVH.
Source: Translational Stroke Research - July 19, 2022 Category: Neurology Source Type: research
