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Ethnic Disparities in Ischemic Stroke, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage Incidence in The Netherlands Clinical Sciences
Conclusions— Our findings suggest that Surinamese have an increased risk, whereas Moroccans have a reduced risk for all the various stroke subtypes. Among other ethnic minorities, the risk seems to depend on the stroke subtype and sex. These findings underscore the need to identify the root causes of these ethnic differences to assist primary and secondary prevention efforts.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Agyemang, C., van Oeffelen, A. A. M., Norredam, M., Kappelle, L. J., Klijn, C. J. M., Bots, M. L., Stronks, K., Vaartjes, I. Tags: Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Innovative Magnetic Resonance Imaging Markers of Hereditary Cerebral Amyloid Angiopathy at 7 Tesla Brief Report
Background and Purpose—The aim of the present study is to explore whether using 7 Tesla magnetic resonance imaging, additional brain changes can be observed in hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D) patients as compared with the established magnetic resonance imaging features of sporadic cerebral amyloid angiopathy.Methods—The local institutional review board approved this prospective cohort study. In all cases, informed consent was obtained. This prospective parallel cohort study was conducted between 2012 and 2014. We performed T2*-weighted magnetic resonance imaging performed at 7 Tesla...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Emma A. Koemans, Ellis S. van Etten, Anna M. van Opstal, Gerda Labadie, Gisela M. Terwindt, Marieke J.H. Wermer, Andrew G. Webb, Edip M. Gurol, Steven M. Greenberg, Mark A. van Buchem, Jeroen van der Grond, Sanneke van Rooden Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Vascular Disease Brief Reports Source Type: research

Incidence of Oral Anticoagulant-Associated Intracerebral Hemorrhage in the Netherlands Brief Reports
Conclusions— The annual incidences of ICH and OAC-ICH are relatively high in the Netherlands when compared with international literature.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Schols, A. M. R., Schreuder, F. H. B. M., van Raak, E. P. M., Schreuder, T. H. C. M. L., Rooyer, F. A., van Oostenbrugge, R. J., Staals, J. Tags: Coumarins, Acute Cerebral Hemorrhage Brief Reports Source Type: research

Intracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis Basic Science
Conclusions—CoW regulatory regions link IA-associated SNPs to genes with a potential role in the development of IAs. Our data refine previous predictions on SNPs associated with IA and provide a substantial resource from which candidates for follow-up studies can be prioritized.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Melanie D. Laarman, Marit W. Vermunt, Rachel Kleinloog, Jelkȷe J. de Boer–Bergsma, Netherlands Brain Bank, Gabriel J.E. Rinkel, Menno P. Creyghton, Michal Mokry, Jeroen Bakkers, Ynte M. Ruigrok Tags: Computational Biology, Epigenetics, Gene Expression & Regulation, Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research