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Condition: Ischemic Stroke
Management: Hospitals
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Total 2377 results found since Jan 2013.
Racial and Ethnic Disparities in the Use of Intravenous Recombinant Tissue Plasminogen Activator and Outcomes for Acute Ischemic Stroke
This study investigated possible racial and ethnic disparities in the administration and outcome of recombinant tissue plasminogen activator (rtPA) therapy for acute ischemic stroke in whites, blacks, Hispanics, and Asian/Pacific Islanders. Using the National Inpatient Sample for 2001-2008, we selected patients with a primary diagnosis of acute ischemic stroke who received treatment with rtPA. Patient data were stratified by race (white, black, Hispanic, and Asian/Pacific Islander). We analyzed the association of patient race on rtPA utilization rate, in-hospital morbidity (ie, discharge to long-term facility), intracrania...
Source: Journal of Stroke and Cerebrovascular Diseases - December 12, 2011 Category: Neurology Authors: Deena M. Nasr, Waleed Brinjikji, Harry J. Cloft, Alejandro A. Rabinstein Tags: Original Articles Source Type: research
First Stroke Patients In Florida Treated In UM Stem Cell Trial
The first two stroke patients have been enrolled in a phase 2 clinical trial of a revolutionary new treatment for ischemic stroke being conducted at the University of Miami/Jackson Memorial Hospital. The trial, using a patient's own bone marrow stem cells, is the first intra-arterial stroke stem cell trial in the U.S., and the two UM/Jackson patients are the first in Florida to participate. Led by Dileep Yavagal, M.D...
Source: Health News from Medical News Today - January 29, 2013 Category: Consumer Health News Tags: Stroke Source Type: news
Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke
Anemia is a known predictor of in-hospital mortality among patients with such vascular conditions as acute myocardial infarction, congestive heart failure, and chronic kidney disease. The role of anemia in patients with acute ischemic stroke is less well understood. We sought to examine the association between anemia at hospital admission and the combined outcome of in-hospital mortality and discharge to hospice in patients with acute ischemic stroke. We evaluated data from a retrospective cohort of consecutive ischemic stroke patients presenting within 48 hours of symptom onset at 5 hospitals between 1998 and 2003. Anemi...
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2011 Category: Neurology Authors: Jason J. Sico, John Concato, Carolyn K. Wells, Albert C. Lo, Steven E. Nadeau, Linda S. Williams, Aldo J. Peixoto, Mark Gorman, John L. Boice, Dawn M. Bravata Tags: Original Articles Source Type: research
Determinants of Neurologic Deterioration and Stroke-Free Survival After Spontaneous Cervicocranial Dissections: A Multicenter Study
Patients with spontaneous cervicocranial dissection (SCCD) may experience new or recurrent ischemic events despite antiplatelet or anticoagulant therapy. Treatment with stent placement is an available option; however, the literature on patient selection is limited. Thus, identifying patients at high risk for neurologic deterioration after SCCD is of critical importance. The present study examined the rate of neurologic deterioration in medically treated patients with SCCD and evaluated demographic, clinical, and radiologic factors affecting this deterioration. We retrospectively identified consecutive patients with SCCD ov...
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2011 Category: Neurology Authors: Ameer E. Hassan, Vikram Jadhav, Haralabos Zacharatos, Saqib A. Chaudhry, Gustavo J. Rodriguez, Yousef M. Mohammad, M. Fareed K. Suri, Nauman Tariq, Gabriela Vazquez, Ramachandra P. Tummala, Robert A. Taylor, Adnan I. Qureshi Tags: Original Articles Source Type: research
Repeated Episodes of Ischemic Stroke over a Short Period in a Patient with Essential Thrombocythemia on Anticoagulant Therapy
A 69-year-old man who had essential thrombocythemia, for which he was taking no medications, suddenly developed aphasia and right hemiplegia and was admitted to the hospital. He was thought to have had an embolic stroke and was initially treated with warfarin. Although the international normalized ratio was in the therapeutic range, he had 3 additional ischemic stroke episodes with the same symptoms after the index stroke. Magnetic resonance angiographic examinations revealed serial changes in middle cerebral artery stenosis. After administration of an antiplatelet agent and hydroxyurea, he had no additional strokes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 14, 2012 Category: Neurology Authors: Masaki Naganuma, Kazuya Isoda, Shinsuke Nishi, Kiyotaka Ito, Teruyuki Hirano Tags: Case Reports Source Type: research
Fighting brain damage from stroke using substance naturally found in humans
A molecular substance that occurs naturally in humans and rats was found to "substantially reduce" brain damage after an acute stroke and contribute to a better recovery, according to a newly released animal study by researchers at Henry Ford Hospital.The study, published online before print in Stroke, the journal of the American Heart Association, was the first ever to show that the peptide AcSDKP provides neurological protection when administered one to four hours after the onset of an ischemic stroke.
Source: Health News from Medical News Today - March 14, 2014 Category: Consumer Health News Tags: Stroke Source Type: news
Massive Interventricular Septal Aneurysm and Stroke in a Healthy Young Patient: Guilt by Association?
We describe here the case of an otherwise healthy, 41-year-old man who presented to the hospital with acute-onset confusion and left-sided body weakness attributed to a right middle cerebral artery ischemic stroke. He experienced a nearly complete resolution of deficits following systemic thrombolytic therapy. After an extensive workup, the presumed mechanism of stroke was a thromboembolus that originated in a massive aneurysm of the patient's membranous interventricular septum. Due to a perceived risk of surgical morbidity, the patient was managed conservatively with anticoagulation. He denied further events and reported ...
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2013 Category: Neurology Authors: John C. Stendahl, Amatul S. Hasan, Mengistu A. Simegn Tags: Case Reports Source Type: research
Deleterious Effect of Smoking on Ischemic Stroke Outcomes: Implications for the Role of Chronic Inflammation on Atherosclerotic Plaque Pathogenesis
I have read, with great interest, a recently published article in the Journal of Stroke and Cerebrovascular Diseases by Edjoc et al titled “The prognostic effect of cigarette smoking on stroke severity, disability, length of stay in hospital, and mortality in a cohort with cerebrovascular disease.” The authors performed a retrospective analysis of the Registry of the Canadian Stroke Network to identify the effect of smoking on cerebrovascular disease outcomes. More than 20,000 patients from the registry, spanning an approximately 5-year time interval, were included in the study. Multivariate logistic regression analys...
Source: Journal of Stroke and Cerebrovascular Diseases - March 1, 2014 Category: Neurology Authors: Dale Ding Tags: Letters to the Editor Source Type: research
Acute Stroke Reperfusion Therapy Trends in the Expanded Treatment Window Era
Background: The American Heart Association/American Stroke Association (AHA/ASA) recommended an expansion of the time window for acute ischemic stroke (AIS) reperfusion with intravenous (IV) recombinant tissue plasminogen activator (rt-PA) from 3 to 4.5 hours after symptom onset. We examine rates of IV and intra-arterial (IA) reperfusion before and after the recommendations to track guideline adoption in community practice.Methods: Patients with AIS in the Paul Coverdell National Acute Stroke Registry spanning years 2007-2012 were identified. Trends in rates of IV rt-PA versus IA therapy were examined. Outcomes included s...
Source: Journal of Stroke and Cerebrovascular Diseases - August 25, 2014 Category: Neurology Authors: Ganesh Asaithambi, Xin Tong, Mary G. George, Albert W. Tsai, James M. Peacock, Russell V. Luepker, Kamakshi Lakshminarayan Tags: Original Articles Source Type: research
Cost Burden of Stroke Mimics and Transient Ischemic Attack after Intravenous Tissue Plasminogen Activator Treatment
Treatment decisions for patients with acute stroke symptoms are based on pertinent history, neurologic examination, laboratory studies, and head computed tomography. In this setting, patients with stroke mimic (SM) may mistakenly receive intravenous tissue plasminogen activator (IV-rtPA). The goal of this study was to investigate the excess direct/indirect hospital costs among patients who received IV-rtPA when final diagnosis was not ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 23, 2015 Category: Neurology Authors: Nitin Goyal, Shailesh Male, Ameer Al Wafai, Sushma Bellamkonda, Ramin Zand Source Type: research
Effect of β-Adrenergic Antagonists on In-Hospital Mortality after Ischemic Stroke
Ischemic stroke accounts for 85%-90% of all strokes and currently has very limited therapeutic options. Recent studies of β-adrenergic antagonists suggest they may have neuroprotective effects that lead to improved functional outcomes in rodent models of ischemic stroke; however, there are limited data in patients. We aimed to determine whether there was an improvement in mortality rates among patients who were taking β-blockers during the acute phase of their ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2015 Category: Neurology Authors: Christopher Phelan, Vivek Alaigh, Gil Fortunato, Ilene Staff, Lauren Sansing Source Type: research
Hemorrhagic stroke following use of the synthetic marijuana "spice"
The association between the street drug spice (K-2 or herbal incense), a synthetic marijuana, and intracranial hemorrhage (ICH) has not yet been described, but it has with acute ischemic stroke (AIS),1 seizure, and myocardial infarction.2 Two young patients (31 and 25 years old) independently presented to our hospital with subarachnoid hemorrhage (SAH) after spice inhalation. The first also had 2 large intraparenchymal hemorrhages (IPH); the other also had AIS. Both were previously healthy without hypertension, coagulopathy, bleeding diathesis, thrombocytopenia, intracranial aneurysm, arteriovenous malformation, connective...
Source: Neurology - September 28, 2015 Category: Neurology Authors: Rose, D. Z., Guerrero, W. R., Mokin, M. V., Gooch, C. L., Bozeman, A. C., Pearson, J. M., Burgin, W. S. Tags: Stroke in young adults, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Other toxicology, Intracerebral hemorrhage CLINICAL/SCIENTIFIC NOTES Source Type: research
Rates of Adverse Events and Outcomes among Stroke Patients Admitted to Primary Stroke Centers
To identify the beneficial effects of primary stroke centers (PSCs) certification by Joint Commission (JC), we compared the rates of in-hospital adverse events and discharge outcomes among ischemic stroke patients admitted to PSCs and those admitted to non-PSC hospitals in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2016 Category: Neurology Authors: Saqib A. Chaudhry, Mohammad R. Afzal, Burhan Z. Chaudhry, Taqi T. Zafar, Adnan Safdar, Mounzer Y. Kassab, Syed I. Hussain, Adnan I. Qureshi Source Type: research
Trends and Regional Variation in Hospital Mortality, Length of Stay and Cost in Hospital of Ischemic Stroke Patients in Alberta Accompanying the Provincial Reorganization of Stroke Care
This study aimed to evaluate the trends and regional variation of stroke hospital care in 30-day in-hospital mortality, hospital length of stay (LOS), and 1-year total hospitalization cost after implementation of the Alberta Provincial Stroke Strategy.
Source: Journal of Stroke and Cerebrovascular Diseases - September 19, 2016 Category: Neurology Authors: Arto Ohinmaa, Yufei Zheng, Thomas Jeerakathil, Scott Klarenbach, Unto H äkkinen, Thanh Nguyen, Dan Friesen, Jane Ruseski, Padma Kaul, Ruolz Ariste, Philip Jacobs Source Type: research
