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Source: Journal of the Neurological Sciences
Condition: Ischemic Stroke

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Total 394 results found since Jan 2013.

Modification of the effects of age on clinical outcomes through management of lifestyle-related factors in patients with acute ischemic stroke
This study examined the association between age and clinical outcomes after ischemic stroke, and whether the effect of age on post-stroke outcomes can be modified by various factors.
Source: Journal of the Neurological Sciences - February 14, 2023 Category: Neurology Authors: Yuichiro Ohya, Ryu Matsuo, Noriko Sato, Fumi Irie, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono, Investigators for Fukuoka Stroke Registry Source Type: research

Associations between stroke type, stroke severity, and pre-stroke osteoporosis with the risk of post-stroke fracture: A nationwide population-based study
BackgroundRecognizing the post-stroke fracture risk factors is crucial for targeted intervention and primary fracture prevention. We aimed to investigate whether stroke types, stroke severity, and pre-stroke osteoporosis are associated with post-stroke fracture.MethodsIn a nationwide cohort, we identified previously fracture-free patients who suffered from first-ever stroke, either acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH), between 2003 and 2015. Information regarding stroke severity, osteoporosis, comorbidity, and medication information was collected.
Source: Journal of the Neurological Sciences - May 27, 2021 Category: Neurology Authors: Hung-Ping Wang, Sheng-Feng Sung, Hsin-Yi Yang, Wan-Ting Huang, Cheng-Yang Hsieh Source Type: research

Stroke-prone renovascular hypertensive rat as an animal model for stroke studies: From artery to brain
Abstract: High blood pressure is a main risk factor for both initial and recurrent stroke. Compared to the poststroke situation in normotension, the brain lesion is larger in hypertension, and the treatments may not be as effective. Thus, the results from healthy individuals may not be directly applied to the hypertensive. In fact, the high prevalence of hypertension in stroke patients and its devastating effect urge the necessity to integrate arterial hypertension in the study of stroke in order to better mimic the clinical situations. The first step to do so is to have an appropriate hypertensive animal model for stroke ...
Source: Journal of the Neurological Sciences - August 19, 2013 Category: Neurology Authors: Song-Jie Liao, Ru-Xun Huang, Zhen-Pei Su, Jin-Sheng Zeng, Jian-Wei Mo, Zhong Pei, Ling Li, Yan-Nan Fang, Hua Hong, Hai-Wei Huang Tags: Review Source Type: research

Association of ALOX5AP1 SG13S114T/A variant with ischemic stroke, stroke subtypes and aspirin resistance
Abstract: The important role of genetic variants in the etiology and pathophysiology of stroke is being increasingly recognized. Simultaneously, the influence of genetic factors in the clinical outcome of drug therapy cannot be ignored. 5-lipoxygenase activating (ALOX5AP) gene involved in the synthesis of leukotrienes, has been recognized as an important gene contributing towards susceptibility of stroke risk. Leukotrienes are involved in the physiological mechanism of atherosclerotic events and inflammation. The present study was designed to identify the association of SG13S114T/A polymorphism in ALOX5AP1 gene with risk o...
Source: Journal of the Neurological Sciences - June 10, 2013 Category: Neurology Authors: Vandana Sharma, Sneha Dadheech, Subhash Kaul, A. Jyothy, Anjana Munshi Tags: Original Articles Source Type: research

The impact of stroke on cognitive processing — A prospective event-related potential study
Conclusions: Our results suggest that ERP measurement is an appropriate method for diagnosis and follow-up of cognitive changes after ischemic stroke. In particular the P3 component is an indicator for patients at risk for reinfarction.Highlights:
Source: Journal of the Neurological Sciences - February 27, 2014 Category: Neurology Authors: Leandra Stahlhut, Karl-Heinz Grotemeyer, Ingo-W. Husstedt, Stefan Evers Tags: Original Articles Source Type: research

The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: A meta-analysis of randomized controlled trials
Conclusions: Aspirin plus dipyridamole combination therapy was beneficial in reducing the recurrence of stroke, and did not increase the bleeding event. Hence, aspirin plus dipyridamole combination therapy is effective and safe for the secondary prevention of stroke.
Source: Journal of the Neurological Sciences - July 19, 2013 Category: Neurology Authors: Xia Li, Guoyu Zhou, Xueying Zhou, Shengnian Zhou Tags: Original Articles Source Type: research

Stroke in essential thrombocythemia
Conclusion: Our findings lead us to suppose that ET may be regarded as a risk factor for stroke (mainly of ischemic, small-vessel type), and the early diagnosis and the personalized management of the patient's global vascular risk in the treatment of ET may promote the prevention of further cerebrovascular events.
Source: Journal of the Neurological Sciences - November 1, 2013 Category: Neurology Authors: Éva Pósfai, Imelda Marton, Anita Szőke, Zita Borbényi, László Vécsei, Angéla Csomor, Katalin Sas Tags: Short Communications Source Type: research

Cerebral microbleeds and white matter hyperintensities in cardioembolic stroke patients due to atrial fibrillation: single-centre longitudinal study
Cerebral microbleeds (CMBs) are a potential predictor of future stroke risk with clinical relevance for antithrombotic treatments, especially in ischaemic stroke patients with atrial fibrillation. However, prospective data on CMBs and risk of stroke in this particular stroke population remain scarce. We therefore performed a single centre longitudinal study to investigate CMBs and white matter hyperintensities (WMH) and the risk of future stroke. Consecutive acute stroke patients, admitted during 2008 –2012 for presumed cardioembolic stroke due to non-valvular atrial fibrillation with available follow-up for the occurren...
Source: Journal of the Neurological Sciences - August 23, 2016 Category: Neurology Authors: Andreas Charidimou, Shigeru Inamura, Tatsufumi Nomura, Aya Kanno, Sang Nyon Kim, Toshio Imaizumi Tags: Clinical short communication Source Type: research

Experience of pediatric stroke from a tertiary medical center in North India
Conclusion: AIS is more common than ICH in this study and 8.9% patients died. Infection is the most common cause of pediatric stroke in Northern India which is amenable to therapy and is preventable.
Source: Journal of the Neurological Sciences - December 26, 2012 Category: Neurology Authors: Jayantee Kalita, Gourav Goyal, Usha Kant Misra Tags: Original Articles Source Type: research

Cognitive impairment and hypothymia in post stroke patients
Abstract: 129 patients aged 18–84 in early rehabilitation period of the first hemispheric ischemic stroke and 48 patients with cerebrovascular disorders without stroke in anamnesis were observed. Cognitive functions (MMSE, FAB, Clock Drawing Test, the 5-Word test, attention assessment, Semantic Verbal Fluency test) and emotional sphere (CES-D) were studied. Investigation was carried out twice during the early recovery period 3–4weeks and 3months after the stroke. Statistically significant decrease of cognitive functions in comparison with control group data was revealed. Cognitive deficiency and depressed mood were fix...
Source: Journal of the Neurological Sciences - December 11, 2012 Category: Neurology Authors: L. Pustokhanova, E. Morozova Tags: Original Articles Source Type: research

Use of DWI-only MR protocol for screening stroke mimics
Abstract: Purpose: Patients presenting with focal neurological symptoms may suffer from stroke or stroke mimics. Diffusion weighted MRI (DWI) is highly sensitive for identifying acute ischemia. Therefore, we aimed to explore whether a DWI-only protocol would help differentiate stroke from stroke mimics.Methods: We identified all patients with possible but not definite stroke that underwent DWI-only MRI between 6/2010 and 8/2011. Patients with a positive DWI lesion were compared to those with negative DWI findings on demographics, risk factor profile, final discharge diagnoses, and outcome.Results: A total of 124 patients w...
Source: Journal of the Neurological Sciences - March 15, 2013 Category: Neurology Authors: Roni Eichel, Tamir Ben Hur, John M. Gomori, Jose E. Cohen, Ronen R. Leker Tags: Original Articles Source Type: research

Early initiation of new oral anticoagulants in acute stroke and TIA patients with nonvalvular atrial fibrillation
Conclusions: The NOAC may be safe in acute stroke or TIA patients with NVAF. A large, prospective study is needed to confirm this.
Source: Journal of the Neurological Sciences - June 5, 2013 Category: Neurology Authors: Kensaku Shibazaki, Kazumi Kimura, Junya Aoki, Naoki Saji, Kenichiro Sakai Tags: Original Articles Source Type: research

Stroke warning syndrome: 18 new cases
Conclusion: SWS is an under-recognized syndrome. Intravenous rt-PA treatment seems to have lower efficacy than in other subtypes of strokes, but none of the patients with SWS undergoing treatment presented haemorrhagic transformation or other complications.
Source: Journal of the Neurological Sciences - June 13, 2013 Category: Neurology Authors: Rossana Tassi, Alfonso Cerase, Maurizio Acampa, Paolo D’Andrea, Francesca Guideri, Giuseppe Lo Giudice, Giovanna Marotta, Sandra Bracco, Giuseppe Martini Tags: Short Communictions Source Type: research

Elevated urea level is associated with poor clinical outcome and increased mortality post intravenous tissue plasminogen activator in stroke patients
Conclusions: Elevated serum urea was independently associated with poor clinical outcome and mortality in acute ischaemic stroke patients treated with IV tPA.
Source: Journal of the Neurological Sciences - July 31, 2013 Category: Neurology Authors: Yan Zhang, Leonid Churilov, Atte Meretoja, Sarah Teo, Stephen M Davis, Bernard Yan Tags: Original Articles Source Type: research