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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Ischemic Stroke
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Total 2464 results found since Jan 2013.
Analysis of the Interleukin-1 Receptor Antagonist Gene Variable Number Tandem Repeats in Ischemic Stroke
Conclusion: Our results do not confirm an association between the gene and ischemic stroke in Caucasian patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2014 Category: Neurology Authors: Leema Reddy Peddareddygari, Souvik Sen, Ankit Pahwa, Mark A. Levenstien, Raji P. Grewal Tags: Original Articles Source Type: research
Quality of Life after Intra-arterial Therapy for Acute Ischemic Stroke
Few data exist about health-related quality of life outcomes after intra-arterial therapy (IAT) for acute ischemic stroke (AIS). We assessed stroke-specific quality of life (SS-QOL) in survivors of stroke after IAT. Consecutive patients undergoing IAT for AIS from 2005 to 2010 were retrospectively identified via an institutional database. SS-QOL (using the SS-QOL score) and disability status (modified Rankin Scale [mRS]) were prospectively assessed via mailed questionnaire. We analyzed quality of life (QOL) scores by domain and summary score, with a summary score of 4 or more defined as a good outcome. Analysis of variance...
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2014 Category: Neurology Authors: Melissa M. Cortez, Michael J. Wilder, Molly McFadden, Jennifer J. Majersik Tags: Original Articles Source Type: research
Effect of Blood Pressure Variability on Cardiovascular Outcome in Diabetic and Nondiabetic Patients with Stroke
Conclusions: We show that SBP variability is associated with cardiovascular outcomes in stroke patients without diabetes, but we didn’t find a correlation between SBP variability and cardiovascular outcomes in stroke patients with diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Bu-Xing Chen, Jun-Ping Tian, Hong-Xia Wang, Jie Xu, Feng-He Du, Xing-Quan Zhao Tags: Original Articles Source Type: research
Stroke Severity and Comorbidity Index for Prediction of Mortality after Ischemic Stroke from the Virtual International Stroke Trials Archive–Acute Collaboration
There is increasing interest in the use of administrative data (incorporating comorbidity index) and stroke severity score to predict ischemic stroke mortality. The aim of this study was to determine the optimal timing for the collection of stroke severity data and the minimum clinical dataset to be included in models of stroke mortality. To address these issues, we chose the Virtual International Stroke Trials Archive (VISTA), which contains National Institutes of Health Stroke Scale (NIHSS) on admission and at 24 hours, as well as outcome at 90 days.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2016 Category: Neurology Authors: Thanh G. Phan, Benjamin Clissold, John Ly, Henry Ma, Chris Moran, Velandai Srikanth, VISTA–Acute Collaboration Source Type: research
Trends in cognitive function assessed by a battery of neuropsychological tests after mild acute ischemic stroke
Cognitive impairment is common after stroke. Most acute ischemic stroke (AIS) patients show cognitive decline in neuropsychological assessments in the early phase of stroke.1,2 Post-stroke cognitive impairment (PSCI) is a broad concept that has been used to define cognitive decline, fulfilling established criteria for cognitive impairment within the first six months following a stroke, which includes post-stroke dementia (PSD) and post-stroke cognitive impairment no dementia (PSCIND).3 Previous studies demonstrated that up to 90% of patients with ischemic stroke had cognitive dysfunction on detailed tests in the acute periods.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2020 Category: Neurology Authors: Yi-Ming Yang, Zhong-Min Zhao, Wei Wang, Fang-Ming Dong, Pan-Pan Wang, Yang-Juan Jia, Ning Han, Yan-Li Jia, Jian-Hua Wang Source Type: research
Improvement of Door-to-Imaging Time in Acute Stroke Patients by Implementation of an All-Points Alarm
In patients with acute ischemic stroke, thrombolysis offers an opportunity to effectively reduce disability and dependency. The success of this treatment is time-dependent. The crucial diagnostic step before initiation of treatment is cerebral imaging. With the aim of reducing in-hospital delays, our hospital’s interdisciplinary stroke management group implemented an all-points alarm to improve in-hospital time delay (the period between arrival to the emergency department and performance of cerebral imaging). The alarm simultaneously alerted all involved staff (from the neurologist to in-hospital transport) to the arriva...
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2011 Category: Neurology Authors: Christian H. Nolte, Uwe Malzahn, York Kühnle, Christoph J. Ploner, Jacqueline Müller-Nordhorn, Martin Möckel Tags: Original Articles Source Type: research
Determinants of Emergency Medical Services Use in a Brazilian Population with Acute Ischemic Stroke
This study evaluates the determinants of EMS use in a Brazilian population with acute ischemic stroke. We performed a post hoc analysis of prospectively collected data of consecutive patients admitted to a Brazilian tertiary hospital with acute ischemic stroke. Groups were compared according to their mode of arrival to the hospital: those brought by EMS and those arriving at the hospital by their own means. Among 165 patients evaluated between January and December 2009, 17.6% arrived by EMS and 82.4% arrived by their own means. After multivariate adjustment, individuals with higher National Institutes of Health Stroke Scal...
Source: Journal of Stroke and Cerebrovascular Diseases - October 3, 2011 Category: Neurology Authors: Gustavo W. Kuster, Monique Bueno Alves, Miguel Cendoroglo Neto, Gisele Sampaio Silva Tags: Original Articles Source Type: research
Bleeding Complications Associated with Warfarin Treatment in Ischemic Stroke Patients with Atrial Fibrillation: A Population-Based Cohort Study
Background: Bleeding events are the major obstacle to the widespread use of warfarin for secondary stroke prevention. Previous studies have not examined the use of risk stratification scores to estimate lifetime bleeding risk associated with warfarin treatment in a population-based setting. The purpose of this study is to determine the lifetime risk of bleeding events in ischemic stroke patients with atrial fibrillation (AF) undergoing warfarin treatment in a population-based cohort and to evaluate the use of bleeding risk scores to identify patients at high risk for lifetime bleeding events.Methods: The resources of the R...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Raymond C.S. Seet, Alejandro A. Rabinstein, Teresa J.H. Christianson, George W. Petty, Robert D. Brown Tags: Original Articles Source Type: research
Troponin Elevation Predicts Atrial Fibrillation in Patients with Stroke or Transient Ischemic Attack
Conclusions: cTnI elevation predicts new-onset AF on 24-hour Holter measurement in patients with acute ischemic stroke or TIA and may indicate a poorer prognosis and a higher risk of stroke, MI, and death at 3 months.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2012 Category: Neurology Authors: Isabelle Beaulieu-Boire, Nancy Leblanc, Léo Berger, Jean-Martin Boulanger Tags: Original Articles Source Type: research
The Totaled Health Risks in Vascular Events (THRIVE) Score Predicts Ischemic Stroke Outcomes Independent of Thrombolytic Therapy in the NINDS tPA Trial
Conclusions: The THRIVE score provides accurate prediction of long-term neurologic outcomes in patients with acute ischemic stroke regardless of treatment modality. Both the THRIVE score and tPA administration predict outcome, but the THRIVE score does not influence the impact of tPA on outcome, and tPA administration does not influence the impact of THRIVE score on outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - November 5, 2012 Category: Neurology Authors: Hooman Kamel, Nihar Patel, Vivek A. Rao, Sean P. Cullen, Bonnie S. Faigeles, Wade S. Smith, Alexander C. Flint Tags: Original Articles Source Type: research
Intravenous Thrombolysis with Neuroprotective Therapy by Edaravone for Ischemic Stroke Patients Older than 80 Years of Age
Background: Alteplase, a recombinant tissue plasminogen activator (tPA), was approved for patients with acute ischemic stroke within 3 hours of stroke onset in Japan in October 2005 at a dose of 0.6 mg/kg. The aim of this study was to assess the safety and efficacy of alteplase in elderly patients in Japan.Methods: One hundred twenty-nine consecutive patients who were admitted to our 5 hospital groups and who received intravenous tPA within 3 hours of stroke onset between January 2010 and December 2011 were divided into 2 groups by age (80 years of age [older group]) and by treatment with or without edaravone. Clinical bac...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Syoichiro Kono, Kentaro Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Toru Yamashita, Yoshio Ikeda, Hisashi Narai, Yasuhiro Manabe, Yoshiki Takao, Sanami Kawada, Kenichi Kashihara, Yasushi Takehisa, Satoshi Inoue, Hideki Kiriyama, Koji Abe Tags: Original Articles Source Type: research
Improving the Prediction of Stroke or Death After Transient Ischemic Attack (TIA) by Adding Diffusion-weighted Imaging Lesions and TIA Etiology to the ABCD2 Score
The present study investigated the addition of transient ischemic attack (TIA) etiology and diffusion-weighted imaging (DWI) to the ABCD2 score, creating the ABCDE+ score, to improve the predictive ability of stroke risk or death at 6 months after TIA. We performed a cohort study of 150 consecutive patients with TIA. All patients underwent DWI and all had an etiologic workup and were followed up for 6 months. The area under the receiver operating characteristic curve (AUC) was used to compare the scores' ability to predict the outcome of stroke or death. Multivariate Cox regression analysis was performed to evaluate the as...
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2012 Category: Neurology Authors: Ali Arhami Dolatabadi, Amirhosein Meisami, Hamidreza Hatamabadi, Behnam Mansori, Ali Shahrami, Afshin Amini, Kazem Jamali Tags: Original Articles Source Type: research
Brain Natriuretic Peptide: A Relevant Marker to Rule Out Delayed Atrial Fibrillation in Stroke Patient
Detection of new atrial fibrillation (AF) after ischemic stroke is challenging. The aim of the TARGET-AF study was to identify relevant markers for ruling out delayed AF in stroke patients. Early and prolonged Holter electrocardiography (ECG) monitoring during hospitalization was performed systematically in consecutive acute stroke patients naive to AF (no history of AF or no AF on baseline ECG). All clinical and paraclinical data for routine etiologic assessment were collected. The diagnostic value of all parameters significantly associated with AF was assessed by comparison of area under the receiver operating characteri...
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2012 Category: Neurology Authors: Laurent Suissa, Saskia Bresch, Sylvain Lachaud, Marie Hélène Mahagne Tags: Original Articles Source Type: research
Validation of the 12-Item Stroke-Specific Quality of Life Scale in a Biethnic Stroke Population
This study in patients with ischemic stroke from diverse racial/ethnic backgrounds found that the more efficient 12-item SSQOL is a valid alternative to the full 49-item SSQOL for the assessment of health-related quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2012 Category: Neurology Authors: Kevin A. Kerber, Devin L. Brown, Lesli E. Skolarus, Lewis B. Morgenstern, Melinda A. Smith, Nelda M. Garcia, Lynda D. Lisabeth Tags: Original Articles Source Type: research
Short- and Long-term Survival after Stroke in Hospitalized Patients in Chile: A Nationwide 5-Year Study
Conclusions: Short- and long-term survival after ischemic stroke was heterogeneous by geographic regions and type of health insurance, regardless age and sex were the strongest predictors. This suggests an impact of socioeconomic factors and access to acute management of strokes on survival.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2013 Category: Neurology Authors: Lorena Hoffmeister, Pablo M. Lavados, Cristiane Murta-Nascimento, Miguel Araujo, Verónica V. Olavarría, Xavier Castells Tags: Original Articles Source Type: research
