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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Ischemic Stroke

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Total 2464 results found since Jan 2013.

Phosphodiesterase-5 Inhibitor PF-03049423 Effect on Stroke Recovery: A Double-Blind, Placebo-Controlled Randomized Clinical Trial
The therapeutic potential of phosphodiesterase-5 inhibitor PF-03049423 was evaluated in a phase 2, multicenter, randomized, double-blind, placebo-controlled study of subjects with acute ischemic stroke (Clinical Trial Registration Information: http://www.clinicaltrials.gov, unique identifier: NCT01208233; http://www.clinicaltrialsregister.eu, EudraCT number: 2010-021414-32).
Source: Journal of Stroke and Cerebrovascular Diseases - December 28, 2015 Category: Neurology Authors: Franco Di Cesare, Jessica Mancuso, Phil Woodward, Martin M. Bednar, Peter T. Loudon, A9541004 Stroke Study Group Source Type: research

Endovascular thrombectomy with or without intravenous thrombolysis in acute basilar artery occlusion ischemic stroke: A meta-analysis
It is poorly understood if endovascular thrombectomy (EVT) with or without intravenous thrombolysis (IVT) better facilitates clinical outcomes in patients with acute basilar artery occlusion (BAO) ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2022 Category: Neurology Authors: Gurkirat Singh Kohli, Derrek Schartz, Racquel Whyte, Sajal Medha Akkipeddi, Nathaniel R Ellens, Tarun Bhalla, Thomas K Mattingly, Matthew T Bender Tags: Thrombectomy alone or with thrombolysis in basilar stroke Source Type: research

Geotopographic and Environmental Characteristics of Communities and the Seasonality of Stroke Occurrences
We read with great interest the study by Takizawa et al that was recently published in the Journal of Stroke and Cerebrovascular Diseases describing seasonality in the occurrence of stroke in Japan. The authors analyzed 35,631 registered stroke cases (29,238 ischemic and 6,393 hypertensive hemorrhagic stroke patients) occurring between 1998 and 2007 from the Japanese Standard Stroke Registry Study (JSSRS) database, which is currently the world’s largest hospital-based stroke database, accumulating records from 163 Japanese institutions throughout Japan. To examine seasonal variation in the incidence of ischemic and noni...
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2011 Category: Neurology Authors: Tanvir Chowdhury Turin, Adrian V. Specogna, Nahid Rumana Tags: Letter to the Editor Source Type: research

Imaging Negative Stroke: Diagnoses and Outcomes in Intravenous Tissue Plasminogen Activator–Treated Patients
Conclusions: Because most INS patients were found to have NNCI, which may represent either transient ischemic attack or aborted stroke, and there were no intracerebral hemorrhages in the INS group, our data support the safety of administering IV t-PA to all patients in whom acute ischemic stroke is clinically suspected. We have demonstrated that NNCI patients and stroke mimics are common, and future larger scale prospective studies are required to delineate the true frequencies of each and to evaluate differences in outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Ilana Spokoyny, Rema Raman, Karin Ernstrom, Brett C. Meyer, Thomas M. Hemmen Tags: Original Articles Source Type: research

Stroke Education for Multidisciplinary Medical Personnel in a Rural Area of Japan for Promotion of Hospital Visit of Acute Stroke Patients
Conclusions: Our stroke education method using the FAST mnemonic designed for multidisciplinary medical personnel improved their stroke knowledge. Reorganization of the management of acute stroke and greater stroke knowledge for medical staff are necessary to increase the visits of acute stroke patients in the rural areas.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2014 Category: Neurology Authors: Hiroyuki Kawano, Chiaki Yokota, Fumio Yamamoto, Yoshiteru Mori, Yosuke Mihara, Yukio Ando, Kazuo Minematsu Tags: Original Articles Source Type: research

Cause-specific Mortality after Stroke: Relation to Age, Sex, Stroke Severity, and Risk Factors in a 10-Year Follow-up Study
We investigated cause-specific mortality in relation to age, sex, stroke severity, and cardiovascular risk factor profile in the Copenhagen Stroke Study cohort with 10 years of follow-up. In a Copenhagen community, all patients admitted to the hospital with stroke during 1992-1993 (n = 988) were registered on admission. Evaluation included stroke severity, computed tomography scan, and a cardiovascular risk profile. Cause of death within 10 years according to death certificate information was classified as stroke, heart/arterial disease, or nonvascular disease. Competing-risks analyses were performed by cause-specific Co...
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2012 Category: Neurology Authors: Ulla Brasch Mogensen, Tom Skyhøj Olsen, Klaus Kaae Andersen, Thomas Alexander Gerds Tags: Original Articles Source Type: research

Factor V Leiden and Ischemic Stroke Risk: The Genetics of Early Onset Stroke (GEOS) Study
Conclusions: Among young adults, we found no evidence for an association between FVL and either all ischemic stroke or the subgroup with stroke of undetermined etiology.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2011 Category: Neurology Authors: Ali G. Hamedani, John W. Cole, Yuching Cheng, Mary J. Sparks, Jeffrey R. O'Connell, Oscar C. Stine, Marcella A. Wozniak, Barney J. Stern, Braxton D. Mitchell, Steven J. Kittner Tags: Original Articles Source Type: research

CHADS2 and CHA2DS2-VASc Scores for Prediction of Immediate and Late Stroke after Coronary Artery Bypass Graft Surgery
Conclusions: A significant number of patients may suffer stroke late after CABG, and patients with a high risk of stroke can be identified by CHADS2 and CHA2DS2-VASc scores independently from the presence of pre- or postoperative atrial fibrillation.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Fausto Biancari, Muhammad Ali Asim Mahar, Olli-Pekka Kangasniemi Tags: Original Articles Source Type: research

Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality
Conclusion: Despite being risk factors, prestroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long-term outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki Tags: Original Articles Source Type: research

Poor Recognition of Prompted Treatment Seeking Even with Good Knowledge of Stroke Warning Signs Contribute to Delayed Arrival of Acute Ischemic Stroke Patients in Thailand
In conclusion, good knowledge of stroke warning signs, most severe stroke, onset at workplace, onset during daytime, and ambulance for transportation are not associated with early arrival within 4.5-hours time window. However, sudden-onset nature and prompted treatment seeking may predict early arrival.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2013 Category: Neurology Authors: Sombat Muengtaweepongsa, Warunee Hunghok, Teeranut Harnirattisai Tags: Original Articles Source Type: research

Impact of the 1425G/A Polymorphism of PRKCH on the Recurrence of Ischemic Stroke: Fukuoka Stroke Registry
Conclusions: The 1425G/A polymorphism in PRKCH is not a significant predictor of stroke recurrence in patients with acute ischemic stroke during a 2-year follow-up period.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2014 Category: Neurology Authors: Ryu Matsuo, Tetsuro Ago, Jun Hata, Junya Kuroda, Yoshinobu Wakisaka, Hiroshi Sugimori, Takanari Kitazono, Masahiro Kamouchi, FSR Investigators Tags: Original Articles Source Type: research

Factors Related to Knowledge of Stroke Symptoms and Risk Factors in a Norwegian Stroke Population
Conclusions: Knowledge of stroke symptoms and risk factors in patients with acute cerebrovascular disease seems to be insufficient. Further educational efforts are needed, as better knowledge may improve prevention of stroke and increase the number of patients who can receive thrombolysis.
Source: Journal of Stroke and Cerebrovascular Diseases - May 8, 2014 Category: Neurology Authors: Antje Sundseth, Kashif Waqar Faiz, Ole Morten Rønning, Bente Thommessen Tags: Original Articles Source Type: research

Aspirin Treatment Failure and the Risk of Recurrent Stroke and Death Among Patients with Ischemic Stroke
Conclusions: In a post-hoc analysis of 2 randomized ischemic stroke trials, aspirin treatment failure was not found to be associated with an increased risk of recurrent stroke or death.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2011 Category: Neurology Authors: Alexandros L. Georgiadis, Steve M. Cordina, Gabriela Vazquez, Nauman Tariq, M. Fareed K. Suri, Kamakshi Lakshminarayan, Harold P. Adams, Adnan I. Qureshi Tags: Original Articles Source Type: research

Are Racial Disparities in Stroke Care Still Prevalent in Certified Stroke Centers?
Racial differences in stroke risk and risk factor prevalence are well established. The present study explored racial differences in the delivery of care to patients with acute stroke between Joint Commission (JC)-certified hospitals and noncertified hospitals. A retrospective chart review was conducted in patients sustaining ischemic stroke admitted to 5 JC-certified centers and 5 noncertified hospitals. Demographic data, risk factors, utilization of acute stroke therapies, and compliance with core measures were recorded. Racial disparities were investigated in the entire group as well as for JC-certified and noncertified ...
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2011 Category: Neurology Authors: Pratik Bhattacharya, Flicia Mada, Leeza Salowich-Palm, Sabrina Hinton, Scott Millis, Sam R. Watson, Seemant Chaturvedi, Kumar Rajamani Tags: Original Articles Source Type: research

Identifying a High Stroke Risk Subgroup in Individuals with Heart Failure
Conclusions: The combination of previous stroke/TIA and DM increases the incidence of stroke in participants with HF without AF. No analyzed subgroup had a stroke rate high enough to make it likely that the benefits of warfarin would outweigh the risks.
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2011 Category: Neurology Authors: Patrick M. Pullicino, Leslie A. McClure, Virginia J. Howard, Virginia G. Wadley, Monika M. Safford, James F. Meschia, Aaron Anderson, George Howard, Elsayed Z. Soliman Tags: Original Articles Source Type: research