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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Ischemic Stroke
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Total 2464 results found since Jan 2013.
Short-term Bleeding Events Observed with Clopidogrel Loading in Acute Ischemic Stroke Patients
Discussion: Contrary to our original hypothesis, patients with AIS receiving clopidogrel loading doses within 24 hours of symptom onset did not appear to experience a higher rate of new serious bleeding events during acute hospitalization when compared with patients who did not receive loading doses. The Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke trial is expected to provide insight into the safety of clopidogrel loading as an acute intervention after cerebral ischemia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Lester Y. Leung, Karen C. Albright, Amelia K. Boehme, Joseph Tarsia, Kamal R. Shah, James E. Siegler, Erica M. Jones, Gayle R. Pletsch, Timothy M. Beasley, Sheryl Martin-Schild Tags: Original Articles Source Type: research
Zoster Sine Herpete, Vertebral Artery Stenosis, and Ischemic Stroke
We report an immunocompetent man with common cold symptoms and conjunctivitis, followed by an acute onset of bulbar weakness and hemihypesthesia without preceding skin rash. Acute medullary infarction and left vertebral artery stenosis were detected. VZV infection was finally identified. Zoster sine herpetic interferes with accurate diagnosis of infectious stroke, and vertebral artery involvement is unusual in ischemic stroke in this situation. An unexplained course of ischemic stroke event should be suspected in patients with VZV cerebrovasculopathy, especially in those without conventional stroke risk factors and those...
Source: Journal of Stroke and Cerebrovascular Diseases - September 12, 2012 Category: Neurology Authors: Wei-Hsi Chen, Chi Chui, Hsin-Ling Yin Tags: Case Reports Source Type: research
Sleep Apnea Treatment After Stroke (SATS) Trial: Is It Feasible?
Sleep apnea affects more than half of patients with acute ischemic stroke and is associated with poor stroke outcome. This pilot study assessed the feasibility of a randomized, sham-controlled continuous positive airway pressure (CPAP) trial in subjects with acute ischemic stroke. Subjects identified with sleep apnea based on an apnea-hypopnea index ≥5 on overnight polysomnography or portable respiratory monitoring within 7 days of onset of stroke symptoms were randomized to receive active or sham CPAP for a 3-month period. Objective usage was ascertained by compliance data cards. Subjects, treating physicians, and outco...
Source: Journal of Stroke and Cerebrovascular Diseases - July 25, 2011 Category: Neurology Authors: Devin L. Brown, Ronald D. Chervin, John D. Kalbfleisch, Michael J. Zupancic, Erin M. Migda, Anna Svatikova, Maryann Concannon, Cory Martin, Kevin J. Weatherwax, Lewis B. Morgenstern Tags: Original Articles Source Type: research
Treatment of Acute Stroke in Patients on Dabigatran: A Survey of US Stroke Specialists
Conclusions: There is a remarkable lack of consensus among vascular neurologists regarding the assessment and treatment of acute stroke patients on dabigatran.
Source: Journal of Stroke and Cerebrovascular Diseases - January 14, 2013 Category: Neurology Authors: Igor Rybinnik, Michael T. Mullen, Steven Messe, Scott E. Kasner, Brett Cucchiara Tags: Original Articles Source Type: research
Association between Paroxysmal Atrial Fibrillation and the Left Atrial Appendage Ejection Fraction during Sinus Rhythm in the Acute Stage of Stroke: A Transesophageal Echocardiographic Study
This study aimed to investigate whether left atrial appendage (LAA) dysfunction evaluated by transesophageal echocardiography (TEE) during sinus rhythm is predictable of paroxysmal atrial fibrillation (PAF) as an embolic source in the acute stage of stroke.Methods and Results: We measured and analyzed LAA flow velocity (LAA-FV) and LAA ejection fraction (LAA-EF) in 300 acute ischemic stroke patients by TEE. We divided the acute ischemic stroke patients into 3 groups. The atrial fibrillation (AF) group (n = 58) comprised patients whose TEE was performed during AF rhythm. The PAF group (n = 42) comprised patients with a hist...
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2013 Category: Neurology Authors: Takahiro Shimizu, Tatsuro Takada, Atsuko Shimode, Yuichi Fujita, Noriko Usuki, Bunta Kato, Satoshi Takaishi, Toshikazu Hirayama, Kazuhiko Hanzawa, Yasuhiro Hasegawa Tags: Original Articles Source Type: research
Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis-Dependent Patients in the United States
Conclusions: The 2-fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis-dependent patients who present with acute ischemic stroke warrant a careful assessment of risk–benefit ratio in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2013 Category: Neurology Authors: Nauman Tariq, Malik M. Adil, Fahad Saeed, Saqib A. Chaudhry, Adnan I. Qureshi Tags: Original Articles Source Type: research
C-reactive Protein and Homocysteine Predict Long-term Mortality in Young Ischemic Stroke Patients
Conclusions: There is an independent association between CRP and homocysteine levels obtained several years after ischemic stroke in young adults and subsequent mortality, even when adjusting for traditional risk factors. This association seems to continue for at least 12 years after the measurements.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2013 Category: Neurology Authors: Halvor Naess, Harald Nyland, Titto Idicula, Ulrike Waje-Andreassen Tags: Original Articles Source Type: research
Pulmonary Embolism in a Stroke Patient after Systemic Thrombolysis: Clinical Decisions and Literature Review
We describe a 73-year-old man who arrived at the emergency room within 2 hours of acute onset of left hemiparesis who was treated with rt-PA and suffered a pulmonary embolism 3 days after acute stroke therapy. rt-PA is also a current therapy for pulmonary embolism, but an ischemic stroke in the previous 3 months is an absolute contraindication to thrombolysis because of the high risk of intracranial hemorrhage. We discuss clinical and therapeutic decisions and review the current literature.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2013 Category: Neurology Authors: Fabio Pilato, Rosalinda Calandrelli, Paolo Profice, Giacomo Della Marca, Aldobrando Broccolini, Giuseppe Bello, Maria Grazia Bocci, Marisa Distefano, Cesare Colosimo, Paolo Maria Rossini Tags: Case Reports Source Type: research
Analysis of Peptidome Profiling of Serum from Patients with Early Onset Symptoms of Ischemic Stroke
Conclusions: Analysis of peptidome profiling of serum could be a useful tool in the search for early diagnostic biomarkers of ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Naira Rico Santana, Edgar Zapico Muñiz, Dolores Cocho, Yolanda Bravo, Raquel Delgado Mederos, Joan Martí-Fàbregas Tags: Original Articles Source Type: research
Clinical Deterioration Following Middle Cerebral Artery Hemodynamic Changes after Intravenous Thrombolysis for Acute Ischemic Stroke
Conclusions: Hemodynamic changes in the affected artery occurred in about two-thirds of patients within the first 10 days after receiving intravenous thrombolysis; 18% had hemodynamic deterioration, which was associated with clinical worsening in half of these cases.
Source: Journal of Stroke and Cerebrovascular Diseases - February 25, 2013 Category: Neurology Authors: José Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Yves Samson Tags: Original Articles Source Type: research
Thrombolysis for Ischemic Stroke in Patients with Brain Tumors
Conclusions: In summary, very limited data exist about thrombolysis in patients with brain tumors. Differentiation of tumor by additional neuroimaging before thrombolysis in ischemic stroke is recommended as thrombolysis might be considered in extra-axial benign appearing neoplasms (eg, meningioma) but is not advisable in intra-axial primary or metastatic neoplasm. Further reporting of thrombolysis in patients with brain tumors is recommended.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2013 Category: Neurology Authors: Thorleif Etgen, Ines Steinich, Lukas Gsottschneider Tags: Original Articles Source Type: research
The iScore Predicts Clinical Response to Tissue Plasminogen Activator in Korean Stroke Patients
Background: Despite substantial differences in clinical features between Asian and Western stroke patients, there are no published prognostic tools validated in an Asiatic population for thrombolytic therapy. We assessed the ability of the iScore to predict the clinical response after intravenous thrombolysis with tissue plasminogen activator (tPA) in a Korean stroke population.Methods: We applied the iScore to eligible participants in the nationwide multicenter stroke registry in Korea. Main outcome measures were poor functional outcome defined as having a modified Rankin Scale score 3-6 and death at 3 months. Symptomati...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Tai Hwan Park, Sang-Soon Park, Youngchai Ko, Soo Joo Lee, Kyung Bok Lee, Jun Lee, Kyusik Kang, Jong-Moo Park, Jay Chol Choi, Dong-Eog Kim, Yong-Jin Cho, Keun-Sik Hong, Joon-Tae Kim, Dae-Hyun Kim, Jae-Kwan Cha, Moon-Ku Han, Ji Sung Lee, Juneyoung Lee, Kyun Tags: Original Articles Source Type: research
The Detrimental Effect of Aging on Leptomeningeal Collaterals in Ischemic Stroke
Conclusion: Our findings show that there is a significant interplay between patient age and adequacy of leptomeningeal collateral circulation in patients with proximal MCA occlusion. The relationship could contribute to adverse tissue outcome and thereby to unfavorable clinical outcome observed in elderly patients with ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2013 Category: Neurology Authors: Ethem Murat Arsava, Atay Vural, Erhan Akpinar, Rahsan Gocmen, Seray Akcalar, Kader K. Oguz, Mehmet Akif Topcuoglu Tags: Original Articles Source Type: research
Favorable Functional Recovery in Overweight Ischemic Stroke Survivors: Findings from the China National Stroke Registry
Background: Obesity paradox has been reported because of the inverse relationship between the body mass index (BMI) and mortality in stroke patients. The relationship between BMI and functional recovery in stroke survivors is less well established. We explored the impact of BMI on functional recovery and mortality in stroke patients in the China National Stroke Registry (CNSR).Methods: Patients were consecutively recruited based on a standard protocol and prospectively followed up for outcomes at 3 months after disease onset. Patients were divided into 5 groups according to their BMI: underweight (
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2013 Category: Neurology Authors: Lu Zhao, Wanliang Du, Xingquan Zhao, Liping Liu, Chunxue Wang, Yilong Wang, Anxin Wang, Gaifen Liu, Yongjun Wang, Yuming Xu Tags: Original Articles Source Type: research
Prediction of Major Vascular Events after Stroke: The Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trial
Conclusions: Both a baseline FCRS of 20% or more and a novel predictive model were associated with future MVEs in SPARCL trial subjects. The novel model needs to be validated, and the benefits of using either the FCRS or the novel model in clinical practice needs to be assessed.
Source: Journal of Stroke and Cerebrovascular Diseases - February 26, 2014 Category: Neurology Authors: Bruce Ovbiagele, Larry B. Goldstein, Pierre Amarenco, Michael Messig, Henrik Sillesen, Alfred Callahan, Michael G. Hennerici, Justin Zivin, K.Michael A. Welch, SPARCL Investigators Tags: Original Articles Source Type: research
