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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Ischemic Stroke
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Total 2464 results found since Jan 2013.
Another possible determinant for ischemic stroke with nonvalvular atrial fibrillation other than conventional oral anticoagulant treatment: The relationship between whole blood viscosity and stroke ☆
Prevention of ischemic stroke complication of atrial fibrillation (AF) is the crucial target in the disease. Stroke is largely prevented by warfarin and the introduction of new oral anticoagulants. While warfarin reduces stroke by 60 –70%, new oral anticoagulants provide at least equal success to this reduction with appropriate dose and treatment compliance.1,2 Nonetheless, we still encounter thromboembolic ischemic stroke in clinical practice in AF patients taking oral anticoagulants (OAC) and once experienced, stroke can hav e devastating consequences for the patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2022 Category: Neurology Authors: Sezen Baglan Uzunget, Kader Eliz Sahin Source Type: research
Effect of metformin on outcome after acute ischemic stroke in patients with type 2 diabetes mellitus
Diabetes mellitus is a well-known risk factor for ischemic stroke and is associated with unfavorable outcome after stroke. Metformin is recommended as first-line treatment in these patients. Pre-stroke metformin use might have neuroprotective properties resulting in reduced stroke severity. However, results of the effects of pre-stroke metformin use on functional outcome are conflicting and has not been previously described in patients with type 2 diabetes mellitus regardless of stroke severity or revascularization treatment.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2022 Category: Neurology Authors: C.J.B.A. Kersten, I.L.H. Knottnerus, E. Heijmans, M. Haalboom, A.A.M. Zandbergen, H.M. den Hertog Source Type: research
Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention
Early stroke occurrence after ischemic stroke or transient ischemic attack (TIA) remains a significant risk despite advances in secondary prevention. Ischemic stroke is largely a thromboembolic disease, and major efforts to reduce the early risk of recurrent stroke in patients with non-cardioembolic stroke have focused on antiplatelet strategies.1 Improvements in outcome have been associated with novel antiplatelet strategies, but significant residual risk of ischemic stroke and the potential for major bleeding, including intracranial hemorrhage, limit the effectiveness of these options.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2022 Category: Neurology Authors: Mukul Sharma, Carlos A. Molina, Kazunori Toyoda, Daniel Bereczki, Scott E. Kasner, Helmi L. Lutsep, Georgios Tsivgoulis, George Ntaios, Anna Czlonkowska, Ashfaq Shuaib, Pierre Amarenco, Matthias Endres, Hans Christoph Diener, David Gailani, Anja Kahl, Mar Source Type: research
Stroke survivors ’ preferences for post-stroke self-management programs: A discrete choice experiment
Stroke is a leading cause of serious, long-term disability with physical, emotional, social, and financial consequences that affect both stroke survivors as well as their families. Stroke has an incidence rate of 1.8 per 1000 person-years and a prevalence of 3.7% in Singapore1, and a 2015 report showed that stroke and other cerebrovascular diseases were the 10th most common cause of hospitalization and the 4th leading cause of deaths in the country.2 Further, stroke survivors are at a higher risk of having a transient ischemic attack (TIA),3 or another cerebrovascular attack.
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2023 Category: Neurology Authors: Kinjal Doshi, Stacey Lee Henderson, Denise Ju Ling Seah, Deidre Anne De Silva, Jia Jia Lee, Vinh Anh Huynh, Semra Ozdemir Source Type: research
Association between Inflammatory Biomarkers and Progression of Intracranial Large Artery Stenosis after Ischemic Stroke
Conclusions: In addition to traditional risk factors and baseline radiologic findings, circulating levels of IL-6 measured soon after stroke onset are associated with future ILA progression.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2011 Category: Neurology Authors: Kanako Shimizu, Kana Shimomura, Yoshiaki Tokuyama, Kenzo Sakurai, Kenji Isahaya, Satoshi Takaishi, Bunta Kato, Noriko Usuki, Takahiro Shimizu, Koji Yamada, Yasuhiro Hasegawa Tags: Original Articles Source Type: research
Long-Term Follow-up of Incidental Intracranial Aneurysms in Patients with Acute Ischemic Stroke
Conclusions: In our study, the prevalence of incidental aneurysm among acute ischemic stroke patients was 6.1%. After 2 years of follow-up, there was no aneurysm rupture or subarachnoid hemorrhage, and the diameter and shape of aneurysms did not change except for 1 patient in whom the aneurysm disappeared.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2011 Category: Neurology Authors: Yoon-Sang Oh, Young-Min Shon, Beum Saeng Kim, A-Hyun Cho Tags: Original Articles Source Type: research
The Frequency of Poststroke Infections and Their Impact on Early Stroke Outcome
Introduction: Poststroke infections are the most common medical complications of stroke and can occur in up to 65% of patients. The aim of this study was to assess the rate of infectious complications during hospitalization of stroke patients and to evaluate the impact of infection in general, including each of the urinary tract infection (UTI), pneumonia, and sepsis, on fatal and poor functional outcome at discharge.Methods: This retrospective study enrolled patients who have been diagnosed with acute ischemic stroke treated in a 1-year period. Poor functional outcome at discharge was defined as severe invalidity and incl...
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2013 Category: Neurology Authors: Natasa Popović, Maja Stefanović-Budimkić, Nikola Mitrović, Aleksandar Urošević, Branko Milošević, Mijomir Pelemiš, Djordje Jevtović, Ljiljana Beslać-Bumbaširević, Dejana Jovanović Tags: Original Articles Source Type: research
Screening for NOTCH3 Gene Mutations Among 151 Consecutive Korean Patients with Acute Ischemic Stroke
Conclusions: In this region, NOTCH3 gene mutations are frequently found in acute stroke patients who present with neuroimaging features consistent with advanced small-vessel disease.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2011 Category: Neurology Authors: Jay Chol Choi, Keun-Hwa Lee, Sook-Keun Song, Jung Seok Lee, Sa-Yoon Kang, Ji-Hoon Kang Tags: Original Articles Source Type: research
Low-Normal Systolic Blood Pressure and Secondary Stroke Risk
A recent observational study of>20,000 patients with recent ischemic stroke suggested that systolic blood pressure (SBP) maintained in a low-normal range may be associated with increased risk of recurrent stroke, especially within the first 6 months after the first stroke. Using a distinct cohort, the current study aimed to independently evaluate the relationship between low-normal SBP levels and risk of recurrent stroke through analysis of a trial dataset involving 3680 patients with recent noncardioembolic ischemic stroke aged ≥35 years recruited from 56 centers between September 1996 and May 2003 and followed for 2 ye...
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2012 Category: Neurology Authors: Bruce Ovbiagele Tags: Original Articles Source Type: research
Safety of Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Saccular Intracranial Aneurysms
Conclusions: Intravenous thrombolysis was safe among our patients with acute ischemic stroke and incidental intracranial saccular aneurysm.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2012 Category: Neurology Authors: Manoj K. Mittal, Raymond C.S. Seet, Yi Zhang, Robert D. Brown, Alejandro A. Rabinstein Tags: Original Articles Source Type: research
What Change in the National Institutes of Health Stroke Scale Should Define Neurologic Deterioration in Acute Ischemic Stroke?
Background: Neurologic deterioration (ND) occurs in one-third of patients with stroke. However, the true incidence of ND and risk for adverse outcomes remains unknown because no standardized definition of ND exists. Our study compared the prognostic value of a range of definitions for ND in patients with acute ischemic stroke (AIS).Methods: All patients who presented to our center with AIS within 48 hours of symptom onset between July 2008 and June 2010 were retrospectively identified. Patient demographics, National Institutes of Health Stroke Scale (NIHSS) scores, etiologies of ND, and outcome measures were compared betw...
Source: Journal of Stroke and Cerebrovascular Diseases - June 25, 2012 Category: Neurology Authors: James E. Siegler, Amelia K. Boehme, Andre D. Kumar, Michael A. Gillette, Karen C. Albright, Sheryl Martin-Schild Tags: Original Articles Source Type: research
Antithrombotic Management of Stroke Patients Before Colonoscopy
Conclusions: In this retrospective analysis, there was no significant difference in the occurrence of stroke, myocardial infarction, venous thromboembolism, and major bleeding between patients who had medications continued around the time of colonoscopy versus those who had temporary discontinuation. A prospective, randomized controlled study is warranted to further elucidate this issue.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2012 Category: Neurology Authors: Basel Assaad, Veronica Kemerko Sesi, Renzo Figari, Lonni Schultz, Nithin Thummala, Mohammed Rehman, Arun Chandok, Ann Silverman, Brian Silver Tags: Original Articles Source Type: research
Epidemiology, Pathophysiology, and Treatment of Hypertension in Ischaemic Stroke Patients
Stroke continues to be one of the leading causes of mortality and morbidity worldwide. There are 2 main types of stroke: ischaemic strokes, which are caused by obstruction of the blood vessels leading to or within the brain, and haemorrhagic strokes, which are induced by the disruption of blood vessels. Stroke is a disease of multifactorial aetiology that may develop as an end state in patients with serious vascular conditions—most notably, uncontrolled arterial hypertension—thereby necessitating the effective control of this risk factor to prevent stroke or its recurrence. This paper focuses specifically on the epidem...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Nur Fatirul Hisham, Ulvi Bayraktutan Tags: Review Articles Source Type: research
Population Trends and Disparities in Outpatient Utilization of Neurologists for Ischemic Stroke
Conclusions: Between 1998 and 2009, IS-related outpatient utilization increased substantially to neurologists but declined to generalists. We identified demographic variations in outpatient utilization of neurologists that potentially lead to disparities in stroke evaluation and management.
Source: Journal of Stroke and Cerebrovascular Diseases - December 26, 2011 Category: Neurology Authors: Sudeep Karve, Rajesh Balkrishnan, Eric Seiber, Milap Nahata, Deborah A. Levine Tags: Original Articles Source Type: research
Exclusion Criteria for Intravenous Thrombolysis in Stroke Mimics: An Observational Study
Conclusions: SM patients frequently had exclusion criteria for systemic thrombolysis, the most frequent being presenting beyond the established thrombolytic window.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Alejandro M. Brunser, Sergio Illanes, Pablo M. Lavados, Paula Muñoz, Daniel Cárcamo, Arnold Hoppe, Verónica V. Olavarria, Iris Delgado, Violeta Díaz Tags: Original Articles Source Type: research
