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Source: The American Journal of Medicine
Condition: Ischemic Stroke

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Total 59 results found since Jan 2013.

Management of Acute Ischemic Stroke
The treatment of acute ischemic stroke has undergone a revolution recently with the publication of five positive thrombectomy trials in the early time window, 0-6 hours from stroke onset in 2015 and the more recent publication of two positive late window trials that included carefully selected patients up to 24 hours from stroke onset.1-3 The treatment efficacy of thrombectomy was highly robust in both time windows and the benefits can likely be expanded to less strictly selected patients. The treatment of acute ischemic stroke with thrombectomy built upon the more modest benefits observed previously with i.v.
Source: The American Journal of Medicine - October 25, 2018 Category: General Medicine Authors: Yunyun Xiong, Bharti Manwani, Marc Fisher Tags: Review Source Type: research

Long-term cardiac monitoring after embolic stroke of undetermined source. Search longer – look harder
Ischemic stroke is a heterogeneous syndrome which may result from several causes such as atherosclerosis, small vessel disease and atrial fibrillation.1 Despite an extensive diagnostic work-up during the acute or chronic phase of the ischemic stroke, the cause of ischemic stroke remains unexplained for 20% of patients, termed cryptogenic stroke. 2 3
Source: The American Journal of Medicine - May 14, 2022 Category: General Medicine Authors: Dimitrios Sagris, Stephanie L Harrison, Benjamin J.R Buckley, George Ntaios, Gregory Y.H Lip Source Type: research

Apparent Treatment-Resistant Hypertension among Individuals with History of Stroke or Transient Ischemic Attack
and Purpose. Blood pressure control is a paramount goal in secondary stroke prevention; however, high prevalence of uncontrolled blood pressure and use of multiple antihypertensive medication classes in stroke patients suggest this goal is not being met. We determined the prevalence and factors associated with apparent treatment-resistant hypertension in persons with/without stroke or transient ischemic attack..
Source: The American Journal of Medicine - March 11, 2015 Category: Journals (General) Authors: Virginia J. Howard, Rikki M. Tanner, Aaron Anderson, Marguerite R. Irvin, David A. Calhoun, Daniel T. Lackland, Suzanne Oparil, Paul Muntner Source Type: research

Patent Foramen Ovale Closure for Secondary Prevention of Cryptogenic Stroke: Updated Meta-Analysis of Randomized Clinical Trials
• In patients with recent cryptogenic stroke, percutaneous closure of patent foramen ovale reduced recurrent stroke/transient ischemic attack compared with medical therapy, but was associated with higher risk of new-onset atrial fibrillation/flutter.• Select, young patients (≤60 years) present ing with recent cryptogenic stroke may benefit from percutaneous closure of patent foramen ovale at relatively low procedural risk.
Source: The American Journal of Medicine - December 8, 2017 Category: General Medicine Authors: Muthiah Vaduganathan, Arman Qamar, Ankur Gupta, Navkaranbir Bajaj, Harsh B. Golwala, Ambarish Pandey, Deepak L. Bhatt Tags: Brief Observation Source Type: research

Atrial Fibrillation and Stroke: Epidemiology
Abstract: The statistics for AFib are impressive. (online video available at: http://education.amjmed.com/video.php?event_id=445&stage_id=5&vcs=1). The principal risk with AFib, stroke or thrombotic embolism, is increased 5-fold in some series; AFib accounts for ≥15% of all strokes in the United States, 36% of strokes for individuals aged>80, and up to 20% of cryptogenic strokes, which means>100,000–125,000 embolic strokes per year, of which>20% are fatal. Patients with ischemic stroke and AFib are significantly (P
Source: The American Journal of Medicine - March 24, 2014 Category: Journals (General) Authors: James A. Reiffel Tags: CME multimedia activities Source Type: research

Dabigatran and warfarin for secondary prevention of stroke in atrial fibrillation patients: A nationwide cohort study
This study revealed, that in clinical practice, vitamin K antagonist-experienced patients with a history of stroke or transient ischemic attack who switch to dabigatran therapy may have an increased rate of a recurrent stroke compared to patients persisting with vitamin K antagonist therapy.
Source: The American Journal of Medicine - September 1, 2014 Category: Journals (General) Authors: Torben Bjerregaard Larsen, Lars Hvilsted Rasmussen, Anders Gorst-Rasmussen, Flemming Skjøth, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research

The Reply
Braillon contends that we should have stressed the poor and unacceptable levels of quality of care for ischemic stroke, which was even worse for transient ischemic attack. We do not agree that the quality of care for ischemic stroke was unacceptable and poor.
Source: The American Journal of Medicine - February 22, 2015 Category: Journals (General) Authors: Sripal Bangalore, Lee Schwamm, Eric E. Smith, Inder M. Singh, Li Liang, Gregg C. Fonarow, Deepak L. Bhatt, Get With the Guidelines-Stroke Steering Committee and Investigators Tags: AJM online Source Type: research

Healthy Lifestyle and Functional Outcomes from Stroke in Women
While a healthy lifestyle has been associated with reduced risk of developing ischemic stroke, less is known about its effect on stroke severity.
Source: The American Journal of Medicine - February 17, 2016 Category: Journals (General) Authors: Pamela M. Rist, Julie E. Buring, Carlos S. Kase, Tobias Kurth Tags: Clinical Research Study Source Type: research

LDL-cholesterol and ischemic stroke in patients with non-valvular atrial fibrillation
We examined the association between LDL-C levels and incident stroke in patients with atrial fibrillation treated with direct oral anticoagulants (DOACs).
Source: The American Journal of Medicine - September 27, 2020 Category: General Medicine Authors: Alexander Omelchenko, Tzipi Hornik-Lurie, Hagit Gabay, Saar Minha, Abid Assali, David Pereg Source Type: research

LDL Cholesterol and Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation
We examined the association between LDL-C levels and incident stroke in patients with atrial fibrillation treated with direct oral anticoagulants (DOACs).
Source: The American Journal of Medicine - September 28, 2020 Category: General Medicine Authors: Alexander Omelchenko, Tzipi Hornik-Lurie, Hagit Gabay, Saar Minha, Abid Assali, David Pereg Tags: Clinical Research Study Source Type: research

Ischemic Stroke
This concise review of the epidemiology, pathophysiology, evaluation, acute management, and prevention of ischemic stroke targets internists, family practicioners, and emergency physicians who manage patient with stroke.
Source: The American Journal of Medicine - August 26, 2021 Category: General Medicine Authors: Steven K. Feske Tags: Review Source Type: research

Effects of Anticoagulation on Low-Density Lipoprotein-Cholesterol and Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation
The study by Omelchenko et al1 concluded that, unlike the general population, low-density lipoprotein-cholesterol (LDL-C) levels were not associated with ischemic stroke risk among patients with atrial fibrillation treated with direct oral anticoagulants (DOACs). To arrive at this conclusion, they retrospectively analyzed data of 21,229 patients with a first-time diagnosis of nonvalvular atrial fibrillation treated with DOACs categorized according to the congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack (TIA), vascular disease, age 65 to 74 years, sex category, ...
Source: The American Journal of Medicine - September 28, 2021 Category: General Medicine Authors: Zeeshan H. Ismail, Zekarias T. Asnake, Joshua K. Salabei Tags: Letter Source Type: research

Peripheral Arterial Disease, Stroke, and Mortality in Patients with Atrial Fibrillation
I read the paper by Vitalis et al1 with great interest. The authors assessed the impact of peripheral arterial disease on mortality and stroke in patients with atrial fibrillation. The adjusted hazard ratio (HR) (95% confidence interval [CI]) of peripheral arterial disease in patients with atrial fibrillation for all-cause mortality was 1.34 (1.06-1.70). In addition, the adjusted HR (95% CI) of peripheral arterial disease in patients with nonanticoagulated atrial fibrillation for ischemic stroke was 3.37 (1.25-9.09).
Source: The American Journal of Medicine - February 1, 2022 Category: General Medicine Authors: Tomoyuki Kawada Tags: Letter Source Type: research

Does CHA2DS2-VASc Improve Stroke Risk Stratification in Postmenopausal Women with Atrial Fibrillation?
Abstract: Background: Risk stratification of atrial fibrillation patients with a congestive heart failure (C), hypertension (H), age ≥ 75 (A), diabetes (D), stroke or transient ischemic attack (TIA) (S2) (CHADS2) score of
Source: The American Journal of Medicine - October 18, 2013 Category: Journals (General) Authors: JoEllyn M. Abraham, Joseph Larson, Mina K. Chung, Anne B. Curtis, Kamakshi Lakshminarayan, Jonathan D. Newman, Marco Perez, Kathryn Rexrode, Nawar M. Shara, Allen J. Solomon, Marcia L. Stefanick, James C. Torner, Bruce L. Wilkoff, Sylvia Wassertheil-Smoll Tags: Clinical research studies Source Type: research

Secondary Prevention after Ischemic Stroke or Transient Ischemic Attack
Source: The American Journal of Medicine - March 26, 2014 Category: Journals (General) Authors: Sripal Bangalore, Lee Schwamm, Eric E. Smith, Inder M. Singh, Li Liang, Gregg C. Fonarow, Deepak L. . Bhatt, Get With the Guidelines-Stroke Steering Committee and Investigators Source Type: research