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Source: Medicine
Condition: Ischemic Stroke
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Total 352 results found since Jan 2013.
Endovascular therapy for acute basilar artery occlusion caused by vertebral artery dissection: Case report
We describes a case of basilar artery (BA) occlusion caused by extracranial VAD, in which we used a stent-retriever to achieve thrombectomy in the BA through the contralateral vertebral artery (VA).
Patient concerns:
A 32-year-old male presented with a sudden-onset headache accompanied by articulation disorder, left-sided weakness, and tinnitus in the left ear.
Diagnosis:
Digital subtraction angiography showed the V1 to V2 segment dissection of the left VA and occlusion of the BA.
Interventions:
Thrombectomy was performed through the thinner right VA with three passes of the Solitaire FR device 4 ×â...
Source: Medicine - November 24, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Efficacy of sequential N-butylphthalide therapy on psychiatric and behavioral functions in acute ischemic stroke
This study examined how the sequential therapy of N-butylphthalide (NBP) could effectively improve physical movement, life activities, and psychological disorders in stroke patients.
Methods:
This double-blind, randomized controlled trial included middle-aged or elderly patients with acute ischemic stroke that had commenced within 48 hours before enrolment in the study. The experimental group was administered 100 mL NBP injections twice a day in the first 14 days, and a sequential 200 mg NBP soft capsule 3 times a day for the next 76 days. The control group was administered 100 mL NBP placebo injections ...
Source: Medicine - November 19, 2021 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Vagus nerve stimulation for upper limb motor impairment after ischemic stroke: A meta-analysis
Background:
Upper limb motor impairment is a common complication following stroke. Although few treatments are used to enhance motor function, still approximately 60% of survivors are left with upper limb motor impairment. Several studies have investigated vagus nerve stimulation (VNS) as a potential technique for upper limb function. However, the efficacy and safety of VNS on upper limb motor function after ischemic stroke have not been systematically evaluated. Therefore, a meta-analysis based on randomized controlled trial will be conducted to determine the efficacy and safety of VNS on upper limb motor function aft...
Source: Medicine - November 19, 2021 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Effect of Danhong injection on neurological recovery and adverse events in patients with acute ischemic stroke: A protocol for a randomized, double-blind, placebo-controlled clinical study
This study will evaluate the effect of Danhong injection on neurological recovery and AEs in AIS. The results will provide a reference for the clinical use of AIS.
Source: Medicine - November 19, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
The role of rehabilitation and vitamin D supplementation on motor and psychological outcomes in poststroke patients
Post-Stroke depression affects between 12% and 72% of patients who have suffered a stroke. The association between low serum levels of 25-hydroxyvitamin D (25(OH) D) and increased risk of depression is reported in both stroke and non-stroke patients. Similarly, high 25(OH) D levels might be associated with greater functional improvement during rehabilitation program.
We wanted to investigate the effects of an intensive rehabilitation on poststroke outcomes. We wondered if the daily rehabilitation of motor and cognitive functions could also have an effect on mood and functional abilities in addition to or as an alternati...
Source: Medicine - November 12, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Posterior fossa transient ischemic attack in the setting of bilateral persistent hypoglossal arteries: A case report and literature review
We reported a 54-year old female with posterior fossa TIA due to the coexisting bilateral persistent hypoglossal arteries and left internal carotid artery stenosis.
Diagnosis:
The patient was diagnosed with posterior fossa TIA, bilateral persistent hypoglossal arteries and left internal carotid artery stenosis.
Interventions:
The patient was given aspirin 100 mg/qd and advised to avoid excessive neck movement.
Outcomes:
Symptoms of intermittent subjective dizziness accompanied by nausea were relieved.
Lessons:
Although requires no special treatment, PHA could be accompanied by hypoplasia of ve...
Source: Medicine - November 12, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Quadrantanopia as the only symptom of post-COVID stroke in the occipital pole: Case report
We report a case of a 46-year-old woman with quadrantanopia due to stroke confirmed with brain MRI, secondary to COVID-19 infection with chronically elevated D-dimers and treated with anticoagulation/antithrombotic modalities. Quadrantanopia was the only symptom recognized by the patient of a stroke localized in the occipital pole of the brain.
Diagnosis:
The patient was diagnosed with quadrantanopia due to stroke confirmed with brain MRI, secondary to COVID-19 infection.
Intervention:
Patient underwent ophthalmological examination and MRI.
Outcomes:
A thrombotic or ischemic risks in the chronic recove...
Source: Medicine - November 5, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Short- and long-term mortality after intravenous thrombolysis for acute ischemic stroke: A propensity score-matched cohort with 5-year follow-up
This study aimed to investigate the efficacy of IVT in AIS using propensity score matching, to determine whether IVT could reduce short- and long-term mortality, and to identify risk factors influencing short- and long-term mortality in AIS.
During 2013 to 2014, the nationwide Korea Acute Stroke Assessment registry enrolled 14,394 patients with first-ever recorded ischemic stroke. Propensity score matching was used to match IVT and control cases with a 1:1 ratio. The primary outcome was survival up to 3 months, 1 year, and 5 years, as assessed using Kaplan–Meier estimates and Cox proportional hazards.
In tota...
Source: Medicine - November 5, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Association of total cholesterol and atherosclerotic cardiovascular disease in patients with follicular thyroid cancer: A real-world study from Chinese populations
The association between serum total cholesterol (TC) level and incident atherosclerotic cardiovascular disease (ASCVD) in patients with follicular thyroid cancer postthyroidectomy is unknown.
This was a retrospective study and patients (n = 384) were divided into low and high TC groups according to the median TC level. Incidence of composite ASCVD (myocardial infarction, ischemic stroke, and cardiovascular death) was compared between these 2 groups and factors contributing to the association of TC and ASCVD were evaluated.
Patients in the high TC group were older and more likely to have diabetes and have higher C...
Source: Medicine - October 1, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Vertebral artery hypoplasia as an independent risk factor of posterior circulation atherosclerosis and ischemic stroke
Vertebral artery hypoplasia (VAH) is a frequent anatomical variation of vertebral arteries, with emerging evidence suggesting that it contributes to posterior circulation ischemia. However, the relationship between VAH and ischemic stroke remains unknown. Hence, this study aimed to determine the prevalence of VAH in patients diagnosed with acute ischemic stroke who were followed up in a neurology clinic and to determine if it can potentially be a risk factor for atherosclerotic stenosis in vertebrobasilar circulation.
This retrospective study included 609 patients diagnosed with acute ischemic stroke between January 1, ...
Source: Medicine - September 24, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Reversible cerebral vasoconstriction syndrome with basilar artery stenosis: A case report
Conclusions:
A headache in young patients with risk factors of atherosclerosis, such as smoking history, uncontrolled hypertension, and dyslipidemia may be caused by reversible cerebral vasoconstriction syndrome or ischemic stroke, which has fatal neurological complications. Therefore, reversible cerebral vasoconstriction syndrome or ischemic stroke should be suspected and appropriately evaluated in such patients, even if the headache is not the thunderclap type.
Source: Medicine - September 24, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Predictors of hemorrhagic complications after intravenous thrombolysis in acute cerebral infarction patients: A single-center study of 391 cases
This study aimed to analyze the risk factors of hemorrhagic complications after intravenous thrombolysis using Urokinase in acute cerebral infarction (ACI) patients.
Total 391 consecutive ACI patients were enrolled and divided into 2 groups: the hemorrhagic complications group and the non-hemorrhagic complications group. The related data were collected and analyzed.
Univariate analysis showed significant differences in prothrombin time, atrial fibrillation (AF), Mean platelet volume, large platelet ratio (L-PLR), triglyceride (TG), Lactate dehydrogenase, alanine aminotransferase (ALT), high-density lipoprotein, and b...
Source: Medicine - September 17, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Prognostic value of red blood cell distribution width in predicting 3-month functional outcome of patients undergoing thrombolysis treatment for acute ischemic stroke
This study was performed to determine whether red blood cell distribution width (RDW) is associated with 3-month poor functional outcome in patients undergoing thrombolytic therapy for acute ischemic stroke.
RDW was measured in patients with thrombolytic therapy in emergency department. Functional outcome was assessed after 3 months and poor functional outcome was defined as modified Rankin scale 3 to 6.
A total of 240 patients were enrolled, and 82 (34.2%) had a poor functional outcome. The median RDW was significantly elevated in patients with a poor functional outcome compare with those with a good outcome. RDW ...
Source: Medicine - September 17, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Exploring community-dwelling stroke survivors’ experiences of receiving a nurse-led theory-based stroke self-management programme: A qualitative study
This study concurred that the SSMP enhanced stroke survivors’ self-efficacy in self-management. Rearrangement of the programme format and enhancements in accessibility could be further examined to enable more effective stroke self-management.
Source: Medicine - September 17, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
A retrospective study on the preventive effect of statin after carotid artery stenting
This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS).
Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatment) and control group (routine treatment), each group 50 patients. Outcomes consisted of degree of nerve defect (as measured by National Institute of Health Stroke Scale), lipid profiles (mg/dL), and CAS complications within 30 days after surgery.
After treatment, there were no significant differences in National Instit...
Source: Medicine - September 3, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
