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Source: International Journal of Stroke
Condition: Ischemic Stroke

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Total 291 results found since Jan 2013.

Heavy ethanol consumption aggravates the ischemic cerebral injury by inhibiting ALDH2
International Journal of Stroke,Volume 10, Issue 8, Page 1261-1269, December 2015.
Source: International Journal of Stroke - July 14, 2015 Category: Neurology Source Type: research

Direct medical cost of stroke in Singapore
ConclusionThere is a considerable economic burden associated with stroke in Singapore. The type of stroke, length of poststroke period, and stroke complications and comorbidities are found to be associated with the total costs. Efforts to reduce inpatient costs and to allocate health resources to focus on the primary prevention of stroke should become a priority.
Source: International Journal of Stroke - July 14, 2015 Category: Neurology Authors: Charmaine Shuyu Ng, Matthias Paul Han Sim Toh, Jiaying Ng, Yu Ko Tags: Research Source Type: research

Heavy ethanol consumption aggravates the ischemic cerebral injury by inhibiting ALDH2
ConclusionsHigh concentrations of ethanol aggravate cerebral injury by inhibiting of aldehyde dehydrogenase 2 and inducing excess accumulation of aldehydes.
Source: International Journal of Stroke - July 14, 2015 Category: Neurology Authors: Wei Wang, Li‐Li Lin, Jin‐Min Guo, Yan‐Qiong Cheng, Jiao Qian, Jawahar L. Mehta, Ding‐Feng Su, Ping Luan, Ai‐Jun Liu Tags: Research Source Type: research

Canadian Stroke Best Practice Recommendations: Hyperacute Stroke Care Guidelines, Update 2015
The 2015 update of the Canadian Stroke Best Practice Recommendations Hyperacute Stroke Care guideline highlights key elements involved in the initial assessment, stabilization, and treatment of patients with transient ischemic attack (TIA), ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and acute venous sinus thrombosis. The most notable change in this 5th edition is the addition of new recommendations for the use of endovascular therapy for patients with acute ischemic stroke and proximal intracranial arterial occlusion. This includes an overview of the infrastructure and resources required ...
Source: International Journal of Stroke - July 6, 2015 Category: Neurology Authors: Leanne K. Casaubon, Jean‐Martin Boulanger, Dylan Blacquiere, Scott Boucher, Kyla Brown, Tom Goddard, Jacqueline Gordon, Myles Horton, Jeffrey Lalonde, Christian LaRivière, Pascale Lavoie, Paul Leslie, Jeanne McNeill, Bijoy K. Menon, Brian Moses, Melani Tags: Guidelines Source Type: research

The European Stroke Organisation Guidelines: a standard operating procedure
In 2008, the recently founded European Stroke Organisation published its guidelines for the management of ischemic stroke and transient ischemic attack. This highly cited document was translated in several languages and was updated in 2009. Since then, the European Stroke Organisation has published guidelines for the management of intracranial aneurysms and subarachnoidal hemorrhage, for the establishment of stroke units and stroke centers, and recently for the management of intracerebral hemorrhage. In recent years, the methodology for the development of guidelines has evolved significantly. To keep pace with this progres...
Source: International Journal of Stroke - July 6, 2015 Category: Neurology Authors: George Ntaios, Natan M. Bornstein, Valeria Caso, Hanne Christensen, Jacques De Keyser, Hans‐Christoph Diener, Exuperio Diez‐Tejedor, Jose M. Ferro, Gary A. Ford, Armin Grau, Emanuella Keller, Didier Leys, David Russell, Danilo Toni, Guillaume Turc, Ba Tags: Guidelines Source Type: research

Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and TIA: a systematic review and meta‐analysis
ConclusionsThe clinical and prognostic significance of poststroke atrial fibrillation episodes shorter than 30 s is unknown. The high frequency of poststroke atrial fibrillation episodes shorter than 30 s justify further investigation into the risk of stroke recurrence and the risk–benefit profile of anticoagulation for this patient population.
Source: International Journal of Stroke - July 6, 2015 Category: Neurology Authors: Luciano A. Sposato, Lauren E. Cipriano, Patricia M. Riccio, Vladimir Hachinski, Gustavo Saposnik Tags: Systematic review Source Type: research

European Stroke Organisation (ESO) guidelines for the management of temperature in patients with acute ischemic stroke
ConclusionsThe currently available data about the management of temperature in patients with acute ischemic stroke are limited, and the strengths of the recommendations are therefore weak. We call for new randomized controlled trials as well as recruitment of eligible patients to ongoing randomized controlled trials to allow for better‐informed recommendations in the future.
Source: International Journal of Stroke - July 1, 2015 Category: Neurology Authors: George Ntaios, Tomasz Dziedzic, Patrik Michel, Vasileios Papavasileiou, Jesper Petersson, Dimitre Staykov, Brenda Thomas, Thorsten Steiner, Tags: Guidelines Source Type: research

Management of ischemic stroke in Central and Eastern Europe
We present features of current management of stroke in Central and Eastern European countries.
Source: International Journal of Stroke - July 1, 2015 Category: Neurology Authors: Hrvoje Budincevic, Cristina Tiu, Daniel Bereczki, Janika Kõrv, Alexander Tsiskaridze, Kurt Niederkorn, Anna Czlonkowska, Vida Demarin, Tags: Panorama Source Type: research

A double‐tuned 1H/23Na resonator allows 1H‐guided 23Na‐MRI in ischemic stroke patients in one session
ConclusionsThe use of a double‐tuned 1H/23Na birdcage head coil in a clinical setting ‘allowed sodium intensity measurements’ in a justifiable time also for acute stroke patients, and heterogenous sodium signal intensity in the diffusion weighted imaging lesion might represent differences in tissue damage or repair.
Source: International Journal of Stroke - June 30, 2015 Category: Neurology Authors: Eva Neumaier‐Probst, Simon Konstandin, Judith Ssozi, Christoph Groden, Michael Hennerici, Lothar R. Schad, Marc Fatar Tags: Research Source Type: research

Prognostic importance of weight change on short‐term functional outcome in acute ischemic stroke
ConclusionsShort‐term weight loss after stroke appears to be more common than we expected, and our results suggest that it is associated with unfavorable functional outcomes. Therefore, clinical nutrition should be considered as a component of medical treatment and weight loss should be monitored as an indicator of malnutrition.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Yerim Kim, Chi Kyung Kim, Seunguk Jung, Sang‐Bae Ko, Seung‐Hoon Lee, Byung‐Woo Yoon Tags: Research Source Type: research

A comparison of location of acute symptomatic vs. ‘silent’ small vessel lesions
ConclusionsLesions that present with acute lacunar ischaemic stroke symptoms may be more likely noticed by the patient through affecting the main motor and sensory tracts, whereas white matter hyperintensity and asymptomatic lacunes mainly affect other areas. Brain location could at least partly explain the symptomatic vs. covert development of small vessel disease.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Maria del C. Valdés Hernández, Lucy C. Maconick, Susana Muñoz Maniega, Xin Wang, Stewart Wiseman, Paul A. Armitage, Fergus N. Doubal, Stephen Makin, Cathie L. M. Sudlow, Martin S. Dennis, Ian J. Deary, Mark Bastin, Joanna M. Wardlaw Tags: Research Source Type: research

Dynamic changes of intramural hematoma in patients with acute spontaneous internal carotid artery dissection
ConclusionsSpatial and temporal dynamics of intramural hematomas after spontaneous internal carotid artery dissection showed an early volume increase with concomitant progression of the internal carotid artery stenosis in 5 of 10 patients. Although spontaneous internal carotid artery dissection overall carries a good prognosis with spontaneous hematoma resorption in all our patients, early follow‐up imaging may be considered, especially in case of new clinical symptoms.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Mirjam R. Heldner, Mila Nedelcheva, Xin Yan, Johannes Slotboom, Etienne Mathier, Justine Hulliger, Rajeev K. Verma, Matthias Sturzenegger, Simon Jung, Corrado Bernasconi, Marcel Arnold, Roland Wiest, Urs Fischer Tags: Research Source Type: research

Combined lysis of thrombus with ultrasound and systemic tissue plasminogen activator for emergent revascularization in acute ischemic stroke (CLOTBUST‐ER): design and methodology of a multinational phase 3 trial
ConclusionsSince intravenous recombinant tissue‐plasminogen‐activator remains the only medical therapy to reverse ischemic stroke applicable in the emergency department, our trial will determine if the additional use of transcranial ultrasound improves functional outcomes in patients with severe acute ischemic stroke (NCT#01098981).
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Peter D. Schellinger, Andrei V. Alexandrov, Andrew D. Barreto, Andrew M. Demchuk, Georgios Tsivgoulis, Martin Kohrmann, John Alleman, Virginia Howard, George Howard, Anne W. Alexandrov, Gordon Brandt, Carlos A. Molina, Tags: Protocol Source Type: research

Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Following Stroke practice guidelines, update 2015
Every year, approximately 62 000 people with stroke and transient ischemic attack are treated in Canadian hospitals, and the evidence suggests one‐third or more will experience vascular‐cognitive impairment, and/or intractable fatigue, either alone or in combination. The 2015 update of the Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Module guideline is a comprehensive summary of current evidence‐based recommendations for clinicians in a range of settings, who provide care to patients following stroke. The three consequences of stroke that are the focus of the this guideline (poststrok...
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Gail A. Eskes, Krista L. Lanctôt, Nathan Herrmann, Patrice Lindsay, Mark Bayley, Laurie Bouvier, Deirdre Dawson, Sandra Egi, Elizabeth Gilchrist, Theresa Green, Gord Gubitz, Michael D. Hill, Tammy Hopper, Aisha Khan, Andrea King, Adam Kirton, Paige Moorh Tags: Guidelines Source Type: research