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Plasma Trimethylamine- < em > N < /em > -Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis
Conclusions Plasma TMAO levels are associated with incident ischemic stroke in a diverse population. Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00005133.PMID:37581385 | DOI:10.1161/JAHA.122.029230
Source: Atherosclerosis - August 15, 2023 Category: Cardiology Authors: Rozenn N Lemaitre Paul N Jensen Zeneng Wang Amanda M Fretts Colleen M Sitlani Ina Nemet Nona Sotoodehnia Marcia C de Oliveira Otto Weifei Zhu Matt Budoff W T Longstreth Bruce M Psaty David S Siscovick Stanley L Hazen Dariush Mozaffarian Source Type: research

Correlation Between Intracranial Calcification and Extracranial Stenosis of the Internal Carotid Artery
We examined a population not selected for cerebral disease. This retrospective study contained 179 subjects aged 18 years and older from the Hawaii Diagnostic Radiology database. Extracranial internal carotid artery stenosis was determined using the absolute diameter, North American Symptomatic Carotid Endarterectomy Trial, and common carotid artery methods. Calcification was scored using the modified Woodcock method. A positive correlation between intracranial calcification and extracranial carotid stenosis was found using all three methods. Individuals with intracranial calcification were more likely to be older, have a ...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Julia R Jahansooz Andrew Ko Ryoko Hiroi Masako Matsunaga Enrique Carrazana Jason Viereck Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
Curr Neurol Neurosci Rep. 2023 Apr 11. doi: 10.1007/s11910-023-01266-2. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Stroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and antic...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Kunal Bhatia Lindsey M Ladd Kelsey H Carr Mario Di Napoli Jeffrey L Saver Louise D McCullough Maryam Hosseini Farahabadi Diana L Alsbrook Archana Hinduja Jorge G Ortiz Garcia Sara Y Sabbagh Alibay Jafarli Afshin A Divani Source Type: research

Outcomes with IV tenecteplase and IV alteplase for acute ischemic stroke with or without thrombectomy in real-world settings in the United States
J Stroke Cerebrovasc Dis. 2022 Dec 6;32(2):106898. doi: 10.1016/j.jstrokecerebrovasdis.2022.106898. Online ahead of print.NO ABSTRACTPMID:36493706 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106898
Source: Atherosclerosis - December 9, 2022 Category: Cardiology Authors: Adnan I Qureshi William I Baskett Navpreet K Bains Brandi R French Farhan Siddiq Camilo R Gomez Chi-Ren Shyu Source Type: research

The Sky's the Limit: Expanding Nursing's Contribution to Acute Stroke Science
Am J Crit Care. 2022 Jul 1;31(4):266-274. doi: 10.4037/ajcc2022109.ABSTRACTStroke is the number one cause of preventable disability in adults in the United States. Significant advances have occurred in medications and technology supporting rapid stroke diagnosis and treatment during the past 30 years, along with blurring of the lines of what traditionally constituted nursing or medical research. Ischemic stroke is a disease of vascular insufficiency that mirrors myocardial infarction more than any other neurologic diagnosis. My primary program of research is focused on exploration of methods to improve intracranial blood f...
Source: Atherosclerosis - June 30, 2022 Category: Cardiology Authors: Anne W Alexandrov Source Type: research