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Ischemic Stroke in the Very Elderly: Experience from an Italian Stroke Unit Hub Over a Period of 8 Years in the Era of Thrombectomy
Industrialized countries witnessed a staggering increase in life expectancy in the last century.1 In Italy, as in many western countries, demographic growth is stagnant and life expectancy reached an average of 84 years old.2 Since age is one of the most important non-modifiable risk factors for stroke,3 the number of patients affected by ischemic stroke will increase and elderly patients, who are particularly susceptible to vascular diseases, will eventually represent the majority of stroke victims.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2021 Category: Neurology Authors: Lorenzo Ricci, Marilena Mangiardi, Jacopo Lanzone, Alfredo De Liso, Adriana Fallacara, Maria Cristina Bravi, Francesca Romana Pezzella, Sabrina Anticoli Source Type: research

Significant Association between OPG/TNFRSF11B Variant and Common Complex Ischemic Stroke
The serum level of osteoprotegerin (encoded by OPG or TNFRSF11B) was previously shown to be increased in patients with ischemic stroke. A single nucleotide polymorphism rs3134069 in the TNFRSF11B gene was previously associated with ischemic stroke in a population of diabetic patients in Italy. It remains to be determined whether rs3134069 is associated with ischemic stroke in the general population or populations without diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - February 28, 2018 Category: Neurology Authors: Xin Xiong, Duraid Hamied Naji, Binbin Wang, Yuanyuan Zhao, Junhan Wang, Dan Wang, Yuting Zhang, Sisi Li, Shanshan Chen, Yufeng Huang, Qin Yang, Xiaojing Wang, Dan Yin, Xin Tu, Qiuyun Chen, Xu Ma, Chengqi Xu, Qing K. Wang Source Type: research