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Severely Disturbed Sleep in Patients With Acute Ischemic Stroke on Stroke Units: A Pilot Study
Conclusion: We show that sleep is severely disturbed in patients with acute ischemic stroke admitted to stroke units. Larger studies are needed to clarify associations between deprivation of deep sleep and secondary deterioration.
Source: Frontiers in Neurology - October 24, 2019 Category: Neurology Source Type: research

Autotitrating Bilevel Positive Airway Pressure in Large Vessel Steno-Occlusive Stroke Patients With Suspected Sleep Apnea: A Multicenter Randomized Controlled Study
Conclusions: In this prematurely terminated trial, auto-BPAP was safe but did not show an effect on short-term clinical outcomes in selected ischemic stroke patients. Its tolerability, however, may be limited in hyperacute stroke care and needs to be improved before larger trials are conducted.Clinical Trial Registration:ClinicalTrials.gov, identifier: NCT01812993.
Source: Frontiers in Neurology - April 13, 2021 Category: Neurology Source Type: research

“I Give It Everything for an Hour Then I Sleep for Four.” The Experience of Post-stroke Fatigue During Outpatient Rehabilitation Including the Perspectives of Carers: A Qualitative Study
ConclusionDespite engaging in outpatient rehabilitation, stroke survivors largely learnt to manage fatigue independent of healthcare professionals. Carers often facilitated learning, monitoring rehabilitation, daily routines and fatigue exacerbation. Conversely, family could be dismissive of fatigue and possess unrealistic expectations. Post-stroke fatigue must be considered by clinicians when delivering outpatient rehabilitation to stroke survivors. Clinicians should consistently screen for fatigue, provide flexible session scheduling, and educate about individual indicators and strategies for management. Clinicians shoul...
Source: Frontiers in Neurology - June 2, 2022 Category: Neurology Source Type: research

Sleep Duration and Stroke: A Mendelian Randomization Study
Conclusions: Our study suggests that sleep duration is not causally associated with risk of stroke and its subtypes.
Source: Frontiers in Neurology - October 6, 2020 Category: Neurology Source Type: research

Relationship between circadian syndrome and stroke: A cross-sectional study of the national health and nutrition examination survey
ConclusionCircadian syndrome was associated with the risk of stroke. Particularly, we should pay more close attention to the risk of stroke in those populations who were female, non-Hispanic whites, had the symptoms of elevated waist circumference or short sleep.
Source: Frontiers in Neurology - August 11, 2022 Category: Neurology Source Type: research

Self-reported cognitive and psychiatric symptoms at 3 months predict single-item measures of fatigue and daytime sleep 12 months after ischemic stroke
ConclusionSelf-reported cognitive and psychiatric symptoms at 3 months predict increased daytime sleep and fatigue at 12 months. This highlights the relevance of monitoring cognitive and psychiatric symptoms in the subacute phase post-stroke. However, future research using validated measures of self-reported symptoms are needed to further explore these relationships.
Source: Frontiers in Neurology - November 17, 2022 Category: Neurology Source Type: research

Passive Properties of the Wrist and Fingers Following Chronic Hemiparetic Stroke: Interlimb Comparisons in Persons With and Without a Clinical Treatment History That Includes Botulinum Neurotoxin
Conclusion: Our results suggest that neural impairments that follow chronic, hemiparetic stroke do not lead to passive mechanical changes within the wrist and finger muscles. Rather, consistent with animal studies, the data points to potential adverse effects of BoNT on passive muscle properties post-stroke, which warrant further consideration.
Source: Frontiers in Neurology - August 10, 2021 Category: Neurology Source Type: research

Impact of Sleep Duration on Depression and Anxiety After Acute Ischemic Stroke
Conclusions: Sleep duration of shorter than 6 h was predictive of anxiety and depression after ischemic stroke.
Source: Frontiers in Neurology - March 26, 2021 Category: Neurology Source Type: research

Associations of sleep apnea risk and oxygen desaturation indices with cerebral small vessel disease burden in patients with stroke
ConclusionIn patients with TIA/minor stroke, high OSA-risk was associated with a greater CSVD burden. Oxygen desaturation indices (ODI and DesDur) rather than AHI were independently associated with global CSVD burden, indicating that longer and more severe desaturations may contribute to the pathogenesis of CSVD.
Source: Frontiers in Neurology - August 25, 2022 Category: Neurology Source Type: research

Relationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke
Conclusion: Our findings indicate a relationship between coronary atherosclerotic burden measured by the CAC score and the severity of sleep apnea. Performing polysomnography could be useful for investigating the severity of hidden coronary artery disease among these patients.
Source: Frontiers in Neurology - July 30, 2019 Category: Neurology Source Type: research

Patient Reported Outcomes Measurements Information System in Stroke Patients in Full and Shortened Format
Conclusion: PROMIS better reflects the overall health status of stroke patients beyond functional outcome as measured by the mRS. Simplification of the questionnaire with a single question per PROMIS domain could potentially replace the full questionnaire, but needs further validation.
Source: Frontiers in Neurology - January 22, 2021 Category: Neurology Source Type: research

Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies
This study aimed to identify independent risk factors for first occurrence of stroke in Chinese individuals based on prospective cohort studies. Forty prospective cohort studies assessing 1,984,552 individuals were selected for the final meta-analysis. The identified risk factors for stroke in the Chinese population included old age (RR = 1.86, 95%CI: 1.47–2.36), hypertension (RR = 2.76, 95%CI: 2.26–3.37), cardiovascular disease history (RR = 1.98, 95%CI: 1.06–3.69), chronic kidney disease (RR = 1.65, 95%CI: 1.36–2.01), diabetes mellitus (RR = 1.71, 95%CI: 1.34–2.18), metabolic syndrome (RR = 1.59, 95%CI: 1.33–...
Source: Frontiers in Neurology - March 18, 2022 Category: Neurology Source Type: research

Efficacy and safety of acupuncture on sleep quality for post-stroke insomnia: a systematic review and meta-analysis
ConclusionAcupuncture could improve sleep quality, has long-term efficacy and without serious adverse events. However, the findings should be treated with caution owing to the existence of methodological quality issues. More studies with rigorous designs are warranted for validation and explored the safety of acupuncture.
Source: Frontiers in Neurology - June 27, 2023 Category: Neurology Source Type: research

Self-Designed Ningxin Anshen Formula for Treatment of Post-ischemic Stroke Insomnia: A Randomized Controlled Trial
In conclusion, self-designed NXAS Formula is effective and safe and has little adverse effect in treating post-stroke insomnia of blood-deficient and liver-heat syndrome.
Source: Frontiers in Neurology - November 9, 2020 Category: Neurology Source Type: research

Factors Associated With Response to Pilot Home-Based Light Therapy for Fatigue Following Traumatic Brain Injury and Stroke
Conclusion: Light therapy may have a greater impact on sleep in younger individuals and those with an evening chronotype. Older individuals may need higher treatment dose to achieve benefit.Clinical Trial Registration:www.anzctr.org.au, identifier: ACTRN12617000866303.
Source: Frontiers in Neurology - July 15, 2021 Category: Neurology Source Type: research

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