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Brainstem strokes are associated with increased obstructive apnea index during sleep acutely after stroke
Sleep-disordered breathing (SDB) and ischemic stroke are intertwined pathologies. Stroke topography may influence SDB presentation. We investigated the association of stroke topography with obstructive (OAI) and central apnea indices (CAI) in acute and subacute stroke.The prospective multicentre SAS-CARE study included 204 stroke patients. Demographic, anthropometric and stroke characteristics were recorded at admission. Stroke topography (left- and right-sided, supra- and infratentorial, cortical, subcortical, insular, brainstem, cerebellar) was visually scored on the MRI at admission and binary coded. Polysomnography was...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Filchenko, I., Dekkers, M., Baillieul, S., Seiler, A., Schmidt, M., Bernasconi, C., Bassetti, C. Tags: Sleep and control of breathing Source Type: research

EAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke
Sleep disorders are highly prevalent in the general population and may be linked in a bidirectional fashion to stroke, which is one of the leading causes of morbidity and mortality. Four major scientific societies established a task force of experts in neurology, stroke, respiratory medicine, sleep medicine and methodology, to critically evaluate the evidence regarding potential links and the impact of therapy. 13 research questions were evaluated in a systematic literature search using a stepwise hierarchical approach: first, systematic reviews and meta-analyses; second, primary studies post-dating the systematic reviews/...
Source: European Respiratory Journal - April 20, 2020 Category: Respiratory Medicine Authors: Bassetti, C. L. A., Randerath, W., Vignatelli, L., Ferini-Strambi, L., Brill, A.-K., Bonsignore, M. R., Grote, L., Jennum, P., Leys, D., Minnerup, J., Nobili, L., Tonia, T., Morgan, R., Kerry, J., Riha, R., McNicholas, W. T., Papavasileiou, V. Tags: Original Articles: EAN/ERS/ESO/ESRS statement Source Type: research

Predicting sleep disordered breathing acutely after stroke: comparing eight sleep questionnaires and a logistic regression model
Conclusion: Neither the questionnaires nor the multivariate model is sufficiently powerful to diagnose SBD in acute stroke patients. Nonetheless, STOP-BANG and SACS are useful to triage acute stroke patients with a higher likelihood for SDB to testing with limited channel sleep studies for early diagnosis and treatment in the acute phase after stroke.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Dekkers, M., Horvath, C., Woerz, V., Duss, S., Schmidt, M., Brill, A.-K., Bassetti, C. Tags: Sleep and control of breathing Source Type: research

The prevalence and risk factors of obstructive sleep apnea in patients with stroke in a tertiary care hospital in India
Conclusion: OSA is highly prevalent in the stroke population with subtle clinical symptoms. BMI was found to be an independent risk factor associated with moderate to severe OSA. A diagnostic sleep study is warranted in stroke patients, particularly with obesity.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Rajagopal, T. V., Christopher, D. J., Isaac, B., Oliver, A., Mathew, V., Sivadasan, A. Tags: Sleep and control of breathing Source Type: research

Pulse-rate variability during sleep studies predicts stroke risk in patients with obstructive sleep apnea
Conclusion: In patients investigated for clinical suspicion of OSA, PRV derived from oximetry during sleep studies allows a reliable prediction of stroke incidence: patients with marked low sympathetic/parasympathetic tone, expressed as a decrease in the LF/HF ratio, were at higher risk of stroke.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Sabil, A., Gerves-Pinquie, C., Blanchard, M., Feuilloy, M., Trzepizur, W., Meslier, N., Goupil, F., Pigeanne, T., Balusson, F., Oger, E., Girault, J.-M., Gagnadoux, F. Tags: Sleep and control of breathing Source Type: research

Sleep disorder level in stroke patients and related factors
Conclusions: In this study, an increase in sleep disorder was detected in stroke patients according to the control group. We found that functional status, sleep quality and depression were related to each other and that sleep quality deteriorated and functional status deteriorated with increasing depressive mood, and sleep quality and depressive mood also affected each other negatively in stroke patients.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Parlak, S., Yılmaz, H., Bekci, T. T., Parlak, L. Tags: Sleep and control of breathing Source Type: research

Thrombolysis and evolution of sleep apnea in ischemic stroke
Conclusions: Sleep apnea is present in the vast majority of newly diagnosed ischemic stroke patients and the prevalence remained high after six months follow-up. Remarkable declining in ESS, ODI4 and hypopneas per hour was observed in the thrombolysis group. Thrombolysis seems to be an independent protective factor for developing sleep apnea post-stroke.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Huhtakangas, J., Saaresranta, T., Huhtakangas, J. Tags: Sleep and control of breathing Source Type: research

Relationship between daytime sleepiness, fatigue severity and respiratory muscle strength in stroke patients
Conclusion: Daytime sleepiness and fatigue levels of stroke patients are related each other, but both of sleepiness and fatigue levels are not related to respiratory muscle strength. Will contribute to improving their participation in daily life activities and quality of life.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Yildiz, A., Mustafaoglu, R., Bardak, A. N. Tags: Rehabilitation and Chronic Care Source Type: research

Benefits of early diagnosis and treatment of obstructive sleep Apnea-Hypopnea syndrome in patients with acute ischemic stroke: SASS (Sleep Apnea in Stroke patients Study)
Conclusions: Acute polygraphy is feasible in patients with AIS. Early treatment of OSAHS could improve stroke outcome, although larger multicentric studies are necessary to confirm these results
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Rodriguez Martin, P. J., Ferrer Galvan, M., Guerrero Zamora, P., Sanchez Gomez, J., Benitez Moya, J. M., Valido Morales, A. S. Tags: Sleep and control of breathing Source Type: research

Hypoxic burden and heart rate variability predict stroke incidence in sleep apnoea
Obstructive sleep apnoea (OSA) is increasingly recognised as a risk factor for stroke [1]. However, the incidence of stroke in patients investigated for OSA has been assessed in a limited number of studies reporting conflicting results on the association between the apnoea–hypopnoea index (AHI) and stroke incidence [1–3].
Source: European Respiratory Journal - March 25, 2021 Category: Respiratory Medicine Authors: Blanchard, M., Gerves-Pinquie, C., Feuilloy, M., Le Vaillant, M., Trzepizur, W., Meslier, N., Goupil, F., Pigeanne, T., Balusson, F., Oger, E., Sabil, A., Girault, J.-M., Gagnadoux, F., on behalf of the ERMES study group Tags: Original Articles: Research letters Source Type: research

The relationship between functional recovery and OSA in Stroke patients of a neurorehabilitation unit in Santiago, Chile
Conclusions: There was a moderate inverse correlation between the value of AHI and the change in FIM. Those patients who presented severity of OSA had less recovery.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Monge, G., Otto-Yanez, M., Torres-Castro, R., Oyarzo, D. Tags: Sleep and control of breathing Source Type: research

Obstructive sleep apnea and cardiovascular risk in Chinese population: a Meta-analysis
Conclusions: This meta-analysis of prospective cohort studies suggests that OSA significantly increases the risk of CHD, stroke and CCVD in Chinese population.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Ye, J., Li, J., Xu, J., Yin, G., Zhan, S. Tags: Clinical Problems Others Source Type: research

Cerebral blood flow (CBF) response to orthostatic stress in patients with obstructive sleep apnea (OSA)
Conclusions:These preliminary results suggest an impairment cerebral vascular reactivity in severe OSA patients related with obesity and oxygen saturation. Diffuse optical techniques may allow noninvasive assessment of the involvement of the cerebral microvasculature.1) B. L. Edlow et al, Physiological Meas 2010.2) T. Durduran et al, Optics Express 2009.This work was funded by SOCAP ( 2011) and SEPAR (2012).
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Cotta Ramusino, G., Fortuna, A., Blanco, I., Mola, A., Zirak, P., Durduran, T., Mayos, M. Tags: 4.2 Sleep and Control of Breathing Source Type: research

OSA results in nocturnal cerebral hypoxia which is prevented by CPAP - Data from a randomised controlled trial
Conclusions: CPAP therapy withdrawal – and thus recurrence of OSA – results in intermittent and sustained nocturnal cerebral tissue deoxygenation to a degree reported to cause functional impairment. These findings suggest that patients with untreated OSA are at increased risk of nocturnal cerebral damage, a threat than can be prevented by CPAP therapy.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Schwarz, E. I., Furian, M., Schlatzer, C., Stradling, J. R., Kohler, M., Bloch, K. E. Tags: 4.2 Sleep and Control of Breathing Source Type: research

Assessing the role of cerebral autoregulation during intrathoracic pressure changes by near infrared spectroscopy (NIRS)
Changes in intrathoracic pressure in obstructive sleep apnea have strong intermittent effects on oxygenation of hemoglobin and left ventricular stroke volume. While compensatory systemic mechanisms are well studied the role of cerebral autoregulation remains essentially unknown. We aimed to compare hemodynamic response in muscle and brain assessed by NIRS during Valsalva- and Müller- maneuvers (VM respectively MM) and thereby describing the role of cerebral autoregulation.In five healthy adults cerebral and muscular NIRS and esophageal pressure (EP) were continuously measured during normal breathing, two VM (EP +15...
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Laures, M., Bolz, N., Zhang, Z., Mensen, A., Schmidt, C., Khatami, R. Tags: 4.2 Sleep and Control of Breathing Source Type: research

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