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Condition: Sleep Disorders
Drug: Lithium
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Total 94 results found since Jan 2013.
Lithium affects the circadian clock in the choroid plexus - A new role for an old mechanism
Biomed Pharmacother. 2023 Jan 24;159:114292. doi: 10.1016/j.biopha.2023.114292. Online ahead of print.ABSTRACTLithium is an effective mood stabilizer, but the mechanism of its therapeutic action is not well understood. We investigated the effect of lithium on the circadian clock located in the ventricle barrier complex containing the choroid plexus (CP), a part of the glymphatic system that influences gross brain function via the production of cerebrospinal fluid. The mPer2Luc mice were injected with lithium chloride (LiCl) or vehicle, and their effects on the clock gene Nr1d1 in CP were detected by RT qPCR. CP organotypic...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - January 26, 2023 Category: Drugs & Pharmacology Authors: Karol ína Liška Tereza Do čkal Pavel Houdek Martin Sl ádek Vendula Lu žná Kateryna Semenovykh Milica Drap šin Alena Sumov á Source Type: research
Factors Associated With Sleep Disturbance Amongst Youth With Bipolar Disorder
CONCLUSIONS: Converging with data from adults, present findings indicate greater sleep disturbance among youth with BD versus HC. Also convergent with adults with BD, mood disturbance, whether depression severity or emotional lability, comprised the predominant correlates of sleep disturbance among youth with BD. Future research is warranted to better understand the temporal association between sleep disturbance and its correlates in youth with BD. Relatedly, interventions that address both mood and sleep disturbances may help improve overall functioning.PMID:36425019 | PMC:PMC9661909
Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry - November 25, 2022 Category: Psychiatry Authors: Jessica Barton Megan Mio Vanessa Timmins Rachel H B Mitchell Brian J Murray Benjamin I Goldstein Source Type: research
