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Total 2 results found since Jan 2013.

Valproic acid decreases vascular smooth muscle cell proliferation via protein phosphatase 2A-mediated p70 S6 kinase inhibition
In conclusion, our results demonstrate that VPA decreased cell proliferation via PP2A-mediated inhibition of p-p70S6K-Thr389 in basal and PDGF-stimulated VSMCs. The results suggest that VPA could be used in the treatment and prevention of atherosclerosis and in-stent restenosis.PMID:35339758 | DOI:10.1016/j.bbrc.2022.03.100
Source: Atherosclerosis - March 27, 2022 Category: Cardiology Authors: Hansol Lee Yun-Jin Hwang Jung-Hyun Park Du-Hyong Cho Source Type: research