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Source: Current Vascular Pharmacology
Condition: Septic Shock
Drug: Insulin
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Kinin Receptors in Vascular Biology and Pathology.
Abstract
Endogenous kinins are important vasoactive peptides whose effects are mediated by two G-Protein-coupled receptors (R), named B2R (constitutive) and B1R (inducible). They are involved in vascular homeostasis, ischemic pre- and post- conditioning, but also in cardiovascular diseases. They contribute to the therapeutic effects of angiotensin-1 converting enzyme inhibitors (ACEI) and angiotensin AT1 receptor blockers. Benefits derive primarily from vasodilatory, antiproliferative, antihypertrophic, antifibrotic, antithrombic and antioxidant properties, which are associated with the release of endothelial fact...
Source: Current Vascular Pharmacology - February 26, 2014 Category: Drugs & Pharmacology Authors: Couture R, Blaes N, Girolami JP Tags: Curr Vasc Pharmacol Source Type: research
