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Study provides deeper insight into long COVID
This study is an important step toward defining long COVID beyond any one individual symptom, " said study author Dr. Leora Horwitz, director of the Center for Healthcare Innovation and Delivery Science and co-principal investigator for the RECOVER Clinical Science Core at NYU Langone Health. " This research definition — which may evolve over time — will serve as a foundation for scientific discovery and treatment design. "The researchers say studying the underlying biological mechanisms of long COVID is central to advancing informed interventions and identifying effective treatment strategies. In addition to establish...
Source: The University of Arizona: Health - May 30, 2023 Category: Universities & Medical Training Authors: mittank Source Type: research

Nanoparticle with mRNA appears to prevent, treat peanut allergies in mice
Key takeawaysPeanuts are one of the most common food allergens for children.UCLA scientists have developed a nanoparticle that delivers mRNA to liver cells in order to teach the immune system to tolerate peanut protein and alleviate allergies.In mice, the nanoparticle successfully dampened symptoms of serious allergy.Peanut allergies affect 1 in 50 children, and the most severe cases lead to a potentially deadly immune reaction called anaphylactic shock.Currently, there is only one approved treatment that reduces the severity of the allergic reaction, and it takes months to kick in. A group of UCLA immunologists is aiming ...
Source: UCLA Newsroom: Health Sciences - April 3, 2023 Category: Universities & Medical Training Source Type: news

UArizona Health Sciences Researchers to Study Long COVID as Part of National Collaborative
This study of post-acute sequelae of SARS-CoV-2, which is aimed at understanding the reasons for persistence of symptoms and organ involvement, assumes tremendous importance for us to devise new treatments and cures to address the long-term consequences of this pandemic, " said Dr.Sairam Parthasarathy, one of the project ' s multiple principal investigators.In addition to Parthasarathy, who is a professor of medicine and chief of the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine at the UArizona College of Medicine – Tucson and a BIO5 Institute member, principal investigators include Dr.Marilyn Glassber...
Source: The University of Arizona: Health - December 16, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

Respiratory Tract Bacterial Extracts Could Prevent COVID-19
This study is unique because it is the first time researchers have targeted the receptor – the lock – with a bacterial extract and shown it protects against infection with live virus. We ' re essentially removing the lock from the cell wall so there ' s nothing for the virus ' key to attach to, " said senior author Dr.  Donata Vercelli, professor of  cellular and molecular medicine at the UArizona College of Medicine – Tucson and professor of genetics at the BIO5 Institute.  When SARS-CoV-2 enters the lungs, it binds to receptors including the angiotensin converting enzyme 2 receptor, known as ACE2, on the out...
Source: The University of Arizona: Health - December 14, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

Researchers to Study Why COVID-19 Strikes Asthma Sufferers Less Severely Than Others
A University of Arizona Health Sciences-led research team received $7.16 million in federal funding to study how to better control severe asthma and determine why sufferers are less likely to contract COVID-19, influenza and rhinovirus. Today University of Arizona Health Scienceswomen_blowing_nose-948301830-hero-web.jpgHealthCollege of Medicine - TucsonExpertsExplorationResearchAn investigation into why asthma sufferers are less likely to contract COVID-19 is one of several aims for research funded through a $7.16 million National Institutes of Health cooperative agreement with the  Asthma and Airway Disease Research ...
Source: The University of Arizona: Health - December 9, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news

Study Shows SARS-CoV-2 Antibodies Provide Lasting Immunity
Digital media& downloads Study Shows SARS-CoV-2 Antibodies Provide Lasting Immunity UArizona Heath Sciences researchers developed one of the most accurate COVID-19 antibody tests available and now have shown antibodies persist for months after infection, providing long-term immunity. Stacy Pigott Today University of Arizona Health SciencesPresident-Robbins_klh7008-2-web.jpg Staff process samples at blood draw at the UArizona Cole and Jeannie Davis Sports Center, which served as a temporary clinic for antibody testing of first responders and health care workers in late April. Kris Hanning/University of Arizona He...
Source: The University of Arizona: Health - October 13, 2020 Category: Universities & Medical Training Authors: spigott Source Type: research

Single-use N95 respirators can be decontaminated and used again, study finds
N95 respirators,which are widely worn by health care workers treating patients with COVID-19and are designed to be used only once, can be decontaminated effectively and used up to three times, according to research by UCLA scientists and colleagues.An early-release version of their study has beenpublished online, with the full study to appear in September in the journal Emerging Infectious Diseases.N95 respirators reduce exposure to airborne infectious agents,including SARS-CoV-2, the virus that causes COVID-19,and are one of the key pieces of personal protective equipment used by clinical workers in preventing the spread ...
Source: UCLA Newsroom: Health Sciences - August 27, 2020 Category: Universities & Medical Training Source Type: news

UCLA is part of NIH-sponsored clinical trial for possible COVID-19 therapies
UCLA Health is one of 75 sites around the globe participating in a clinical trial sponsored by the National Institutes of Health to test the effectiveness of a candidate antiviral drug against COVID-19.The drug, called remdesivir, was originally developed as a treatment for Ebola. Although it was found to be safe, it was not effective in treating patients with the disease. In laboratory tests, however, it appears to work against the SARS-CoV-2 virus that  causes COVID-19, which has raised hope that it may be effective against the coronavirus that has swept the globe, sickening and killing thousands.The clinical trial wa...
Source: UCLA Newsroom: Health Sciences - April 3, 2020 Category: Universities & Medical Training Source Type: news

Study reveals how long COVID-19 remains infectious on cardboard, metal and plastic
The virus that causes COVID-19 remains for several hours to days on surfaces and in aerosols,a new study published in  the New England Journal of Medicine found.The study suggests that people may acquire the coronavirus through the air and after touching contaminated objects. Scientists discovered the virus is detectable for up to three hours in aerosols, up to four hours on copper, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel.“This virus is quite transmissible through relatively casual contact, making this pathogen very hard to contain,” said James Lloyd-Smith, a co-author of...
Source: UCLA Newsroom: Health Sciences - March 20, 2020 Category: Universities & Medical Training Source Type: news