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Source: American Journal of Rhinology and Allergy
Condition: SARS

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Total 18 results found since Jan 2013.

Qualitative Olfactory Dysfunction and COVID-19: An Evidence-Based Review with Recommendations for the Clinician
CONCLUSIONS: While other respiratory viruses are known to cause qualitative olfactory disturbances, the incidence of parosmia following COVID-19 is notable, and correlates negatively with age. The presence of parosmia predicts persistent quantitative olfactory dysfunction. Onset can occur months after infection, and symptoms may persist for well over 7 months. Affected patients report increased anxiety and decreased quality of life. Structured olfactory training with essential oils is the preferred treatment, where parosmia predicts recovery of aspects of quantitative smell loss when undergoing training. There is limited e...
Source: American Journal of Rhinology and Allergy - August 12, 2022 Category: ENT & OMF Authors: Joseph B Gary Liam Gallagher Paule V Joseph Danielle Reed David A Gudis Jonathan B Overdevest Source Type: research

Effect of Sodium Gluconate on Decreasing Elevated Nasal Calcium and Improving Olfactory Function Post COVID-19 Infection
CONCLUSION: Based on the proposed results, sodium gluconate may associate with an improvement of the olfactory dysfunction post-COVID-19 infection.PMID:35942688 | DOI:10.1177/19458924221120116
Source: American Journal of Rhinology and Allergy - August 9, 2022 Category: ENT & OMF Authors: Mohamed H Abdelazim Ahmed H Abdelazim Source Type: research

Intensive Olfactory Training in Post-COVID-19 Patients: A Multicenter Randomized Clinical Trial
CONCLUSION: These data suggest that training intensification by increasing the number of essences for 4 weeks does not show superiority over the classical method. Moreover, fluctuant olfaction seems to be related to a higher score on the UPSIT.PMID:35866202 | DOI:10.1177/19458924221113124
Source: American Journal of Rhinology and Allergy - July 22, 2022 Category: ENT & OMF Authors: Ícaro de A T Pires Sara T Steffens Aurenzo G Mocelin Debora E Shibukawa Let ícia Leahy Fernanda L Saito Nicole T Amadeu Nat ália M D Lopes Ellen C D Garcia Maria L Albanese Laura F De Mari Isabel M Ferreira C ésar A Veiga Yasser Jebahi Herton Coifman Source Type: research

Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis
CONCLUSION: ECRS patients with type 2 inflammation showed decreased ACE2 and TMPRSS2 expressions in their sinus mucosa. ACE2 and TMPRSS2 regulation seems to be positively related to IFN-γ and TNF-α production in CRS patients; ACE2 and TMPRSS2 were co-expressed in the ciliated epithelium of their paranasal mucosa, implicating the paranasal epithelium as a portal for initial infection and transmission.PMID:34989246 | DOI:10.1177/19458924211059639
Source: American Journal of Rhinology and Allergy - January 6, 2022 Category: ENT & OMF Authors: Tomohiro Kawasumi Sachio Takeno Takashi Ishino Tsutomu Ueda Takao Hamamoto Kota Takemoto Yuichiro Horibe Oda Takashi Source Type: research

Regulation of the Expression of SARS-CoV-2 Receptor Angiotensin-Converting Enzyme 2 in Nasal Mucosa
CONCLUSION: Inflammatory endotype affects ACE2 expression in the nasal mucosa and influences susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In particular, type 2 inflammation could downregulate ACE2 expression in the nasal mucosa and reduces susceptibility to SARS-CoV-2 in patients with CRSwNP. Although in vivo experiments are required, administration of SCFAs to the nasal cavity might be worthy of consideration as a preventative or therapeutic strategy for the early-stage COVID-19.PMID:34232770 | DOI:10.1177/19458924211027798
Source: American Journal of Rhinology and Allergy - July 7, 2021 Category: ENT & OMF Authors: Tetsuji Takabayashi Kanako Yoshida Yoshimasa Imoto Robert P Schleimer Shigeharu Fujieda Source Type: research

COVID-19-Induced Anosmia and Ageusia Are Associated With Younger Age and Lower Blood Eosinophil Counts
CONCLUSION: Anosmia and ageusia were more common among younger patients and those with lower blood eosinophil counts. Ageusia was less commonly reported among men, and time to taste recovery was earlier among both men and Latinos.PMID:33813917 | DOI:10.1177/19458924211004800
Source: American Journal of Rhinology and Allergy - April 5, 2021 Category: ENT & OMF Authors: Esha Sehanobish Mali Barbi Valerie Fong Meryl Kravitz Denise Sanchez Tejera Mohammad Asad Cynthia Matsumura Denisa Ferastraoaru Meaghan O'Neill Merhunisa Karagic Nadeem Akbar Danielle M Bottalico Viraj Patel Alexandre Peshansky Mahendra Rangareddy Golda H Source Type: research