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Response to clopidogrel is associated with early neurological deterioration after acute ischemic stroke.
Conclusions: CR and END are fairly common after acute IS. CR is associated with higher risk of END. Clopidogrel plus aspirin combination therapy provides greater inhibition of platelet aggregation, and may afford protection against END. PMID: 29731992 [PubMed]
Source: Oncotarget - May 9, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack.
Conclusion: Serum PDCD11-Ab level may serve as a potential biomarker for TIA. PMID: 29507658 [PubMed]
Source: Oncotarget - March 8, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Relation between baseline plaque features and subsequent coronary artery remodeling determined by optical coherence tomography and intravascular ultrasound.
We examined the influence of baseline plaque characteristics on subsequent vascular remodeling in response to changes in plaque size. Using optical coherence tomography (OCT) and intravascular ultrasound (IVUS), we examined 213 plaques from 138 patients with acute coronary syndrome at baseline and repeated IVUS at the 12-month follow-up. The change in external elastic membrane (EEM) area for each 1 mm2 change in plaque area (i.e., the slope of the regression line) was calculated as a measure of vascular remodeling capacity. In plaques with static positive remodeling, the slope was smaller than in plaques without static pos...
Source: Oncotarget - December 20, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The effect of the severity of obstructive sleep apnea syndrome on telomere length.
In conclusion, our study indicates the presence of an association between LTL and OSAS and a significant impact of severity of OSAS in telomeres shortening. PMID: 27690344 [PubMed - as supplied by publisher]
Source: Oncotarget - October 2, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research