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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Diabetes
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Total 164 results found since Jan 2013.
Significant Association between OPG/TNFRSF11B Variant and Common Complex Ischemic Stroke
The serum level of osteoprotegerin (encoded by OPG or TNFRSF11B) was previously shown to be increased in patients with ischemic stroke. A single nucleotide polymorphism rs3134069 in the TNFRSF11B gene was previously associated with ischemic stroke in a population of diabetic patients in Italy. It remains to be determined whether rs3134069 is associated with ischemic stroke in the general population or populations without diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - February 28, 2018 Category: Neurology Authors: Xin Xiong, Duraid Hamied Naji, Binbin Wang, Yuanyuan Zhao, Junhan Wang, Dan Wang, Yuting Zhang, Sisi Li, Shanshan Chen, Yufeng Huang, Qin Yang, Xiaojing Wang, Dan Yin, Xin Tu, Qiuyun Chen, Xu Ma, Chengqi Xu, Qing K. Wang Source Type: research
The Burden of Diabetes and the Chance of a Previous Stroke: Thrombolysis for Recurrent Stroke in Diabetics
Intravenous thrombolysis with recombinant tissue plasminogen activator is still not approved by the European Medicines Agency for patients with diabetes mellitus and previous stroke. We assessed functional benefit and potential risk of thrombolysis in patients with diabetes and previous stroke and the influence of age, preexisting diabetic damage, as well as acute and chronic hyperglycemia on outcome, symptomatic intracranial hemorrhage, and in-hospital mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2018 Category: Neurology Authors: Alexandra Filipov, Anne D. Ebert, Eva Neumaier-Probst, Angelika Alonso Source Type: research
Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Introduction: Having a low level of physical activity is an established risk factor for stroke, but little is known about the importance of common sedentary behavior —television viewing—to stroke risk. Methods: We conducted a retrospective analysis of data that were collected as part of the longitudinal Australian Diabetes, Obesity, and Lifestyle study. Stroke events reported during the study (between baseline assessment in 1999-2000 and April 2011) were con firmed using adjudication based on medical records.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Toby B. Cumming, Elizabeth Holliday, David Dunstan, Coralie English Source Type: research
Collagen-Induced Platelet Aggregates, Diabetes, and Aspirin Therapy Predict Clinical Outcomes in Acute Ischemic Stroke
This study aimed to identify factors that may affect platelet aggregability and their role in clinical outcomes in acute ischemic stroke. Methods: Consecutive acute ischemic stroke patients (n = 352) who were transferred within 24 hours after its onset were enrolled. Peripheral venous blood was sampled to measure platelet aggregability and other parameters. Results: Mean values of spontaneous small-sized platelet aggregates and collagen- or adenosine diphosphate (ADP)-induced large-s ized aggregates were elevated in acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2019 Category: Neurology Authors: Kaho Harima, Sumika Honda, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Joji Hagii, Hirofumi Metoki, Minoru Yasujima, Tomohiro Osanai Source Type: research
Sodium-Glucose Cotransporter-2 Inhibitors and Protection Against stroke in Patients with type 2 Diabetes and Impaired Renal Function: A Systematic Review and Meta-Analysis
It is well established that diabetes mellitus type 2 (T2DM) is associated with increased risk of cardiovascular disease, including ischemic stroke. Among past antidiabetic agents, only pioglitazone and glucagon-like peptide 1 receptor agonists (GLP-1RA) have been shown to decrease the risk of stroke.1-5 Similarly, sodium-glucose cotransporter-2 inhibitors (SGLT2i) were expected to reduce the risk of stroke, considering their blood pressure lowering and neuroprotective effects demonstrated by experimental studies.
Source: Journal of Stroke and Cerebrovascular Diseases - March 10, 2021 Category: Neurology Authors: Fotios Barkas, Sebastian Filippas Ntekouan, Evangelos Liberopoulos, Theodosios Filippatos, Haralampos Milionis Source Type: research
Chronic Kidney Disease is a Risk Factor for Stroke
Chronic kidney disease (CKD) is a sustained reduction in estimated glomerular filtration rate (eGFR), and/or presence of albuminuria. People with CKD have adverse cardiovascular outcomes including stroke. CKD and stroke share several risk factors, most notably older age, diabetes and hypertension, but CKD is also an independent risk factor for stroke. Relative burden of increased risk is worse for younger people and women, with
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2021 Category: Neurology Authors: Melanie Wyld, Angela C Webster Source Type: research
Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis
Globally, the number of people estimated to have diabetes mellitus (DM) in 2019 was 463 million, and the estimated number is expected to rise to 578 million people by 2030.1 DM is also associated with an increased risk of atrial fibrillation (AF), 2 and has shown to be an independent risk factor for stroke in patients with AF.3 A meta-analysis of 102 studies further showed that patients with diabetes have a higher risk of all subtypes of stroke (ischemic, hemorrhagic and unclassified stroke).4 This has generated great interest in anti-hyperglycemic agents and their ability to reduce the cardiovascular complications of diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2021 Category: Neurology Authors: How Ting Ong, Yao Hao Teo, Yao Neng Teo, Nicholas LX Syn, Caitlin Fern Wee, Shariel Leong, Alicia Swee Yan Yip, Ray Meng See, Adriel Zhi Hen Ting, Alys ZQ Chia, Alex Jia Yang Cheong, Benjamin Yong-Qiang Tan, Jamie Sin-Ying Ho, Leonard Leong-Litt Yeo, Aloy Source Type: research
Effect of Low-Intensity Ergometer Aerobic Training on Glucose Tolerance in Severely Impaired Nondiabetic Stroke Patients
Objective: To investigate whether low-intensity ergometer aerobic training has beneficial effect on glucose tolerance in nondiabetic patients with severely impaired stroke.Methods: Fifty-four severely impaired stroke survivors were recruited and randomly assigned to the experimental group and control group. They have no diabetes history with fasting plasma glucose less than 7 mmol/L. Both groups participated in a 6-week rehabilitation training program with low-intensity ergometer aerobic training added only in the experimental group 3 times per week. Primary outcome variables were fasting glucose, fasting insulin, 2-hour ...
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2013 Category: Neurology Authors: Zun Wang, Lei Wang, Hongjuan Fan, Xiao Lu, Tong Wang Tags: Original Articles Source Type: research
The Impact of Atherosclerotic Factors on Cerebral Aneurysm Is Location Dependent: Aneurysms in Stroke Patients and Healthy Controls
This study included consecutive 283 asymptomatic healthy adults and 173 acute stroke patients, from patients diagnosed with acute cerebral hemorrhage or cerebral infarction and admitted to our hospital. The incidence, maximum diameter, and location of UIAs were evaluated, and we also investigated the following factors: age, gender, current smoking, HT, diabetes mellitus (DM), and dyslipidemia. UIAs were found in 19 of the total 456 subjects (4.2%), 11 of 283 healthy subjects (3.9%), and 8 of 173 stroke patients (4.6%). These differences are not statically significant. The incidence of middle cerebral artery (MCA) aneurysms...
Source: Journal of Stroke and Cerebrovascular Diseases - August 25, 2014 Category: Neurology Authors: Masaaki Hokari, Masanori Isobe, Tetsuaki Imai, Yasuhiro Chiba, Naotaka Iwamoto, Toyohiko Isu Tags: Original Articles Source Type: research
Poor Outcome of Experimental Ischemic Stroke in Type 2 Diabetic Rats: Impaired Circulating Endothelial Progenitor Cells Mobilization
This study tried to investigate whether T2DM worsens the cerebral I/R injury via affecting circulating EPCs.
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2015 Category: Neurology Authors: HongNa Yang, Shuang Ma, Ying Liu, Yi Li, Wei Wu, EnJi Han, GuoYong Jia, CuiLan Wang Source Type: research
Metabolic Syndrome, Its Components, and Diabetes on 5-Year Risk of Recurrent Stroke among Mild-to-Moderate Ischemic Stroke Survivors: A Multiclinic Registry Study
This study aimed to examine these associations.
Source: Journal of Stroke and Cerebrovascular Diseases - December 24, 2015 Category: Neurology Authors: Xianghua Fang, Hongjun Liu, Xinqing Zhang, Hongmei Zhang, Xiaoming Qin, Xunming Ji Source Type: research
Association of Sleep Duration with Stroke in Diabetic Patients: Analysis of the National Health Interview Survey
Habitual sleep duration is increasingly being recognized as an important risk factor for stroke. We sought to describe the association between sleep duration and stroke in a cohort of individuals with diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - December 28, 2015 Category: Neurology Authors: Oluwaseun A. Akinseye, Nwakile I. Ojike, Leah I. Akinseye, Perundurai S. Dhandapany, Seithikurippu R. Pandi-Perumal Source Type: research
Race-Ethnic Disparities in Cardiometabolic Risk Profiles among Stroke Survivors with Undiagnosed Diabetes and Prediabetes in the United States
Up to 25% of the U.S. population has undiagnosed diabetes. Diabetes and stroke both disproportionately afflict race/ethnic minorities. We assessed race/ethnic differences in the prevalence of undiagnosed diabetes, prediabetes, and cardiometabolic risk profiles among stroke survivors in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - August 10, 2017 Category: Neurology Authors: Okkyung Kim, Bruce Ovbiagele, Natalie Valle, Daniela Markovic, Amytis Towfighi Source Type: research
Sex Differences in Outcomes after Stroke in Patients with Diabetes in Ontario, Canada
Outcomes after stroke in those with diabetes are not well characterized, especially by sex and age. We sought to calculate the sex- and age-specific risk of cardiovascular outcomes after ischemic stroke among those with diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - September 13, 2017 Category: Neurology Authors: Mandip S. Dhamoon, John W. Liang, Limei Zhou, Melissa Stamplecoski, Moira K. Kapral, Baiju R. Shah Source Type: research
