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Condition: Diabetes
Countries: Japan Health

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Total 325 results found since Jan 2013.

DNA methylation level of the gene encoding thioredoxin-interacting protein in peripheral blood cells is associated with metabolic syndrome in the Japanese general population
Endocr J. 2021 Oct 14. doi: 10.1507/endocrj.EJ21-0339. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is cluster of metabolic diseases, including abdominal obesity, hyperglycemia, high blood pressure, and dyslipidemia, that directly escalate the risk of type 2 diabetes, heart disease, and stroke. Thioredoxin-interacting protein (TXNIP) is a binding protein for thioredoxin, a molecule that is a key inhibitor of cellular oxidation, and thus regulates the cellular redox state. Epigenetic alteration of the TXNIP-encoding locus has been associated with components of MetS. In the present study, we sought to determine wh...
Source: Endocrine Journal - October 14, 2021 Category: Endocrinology Authors: Mirai Yamazaki Hiroya Yamada Eiji Munetsuna Keisuke Maeda Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yoshiki Tsuboi Koji Ohashi Hiroaki Ishikawa Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki Source Type: research

Work-related factors among people with diabetes and the risk of cardiovascular diseases: A systematic review
CONCLUSIONS: This systematic review summarized the available evidence on work-related factors influencing the risk of CVD in people with diabetes. The findings should be interpreted cautiously pondering the limited evidence and imprecision. We identified only five articles related to the topic, and there were no studies from Japan. The scarcity of studies on work-related factors on the prognosis of diabetic patients implies the need for more research in this field. We recommend further exploration of the topic designing primary studies.PMID:34599639 | PMC:PMC8487164 | DOI:10.1002/1348-9585.12278
Source: Journal of Occupational Health - October 2, 2021 Category: Occupational Health Authors: K M Saif-Ur-Rahman Razib Mamun Yuanying Li Masaaki Matsunaga Atsuhiko Ota Hiroshi Yatsuya Source Type: research