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Specialty: Molecular Biology
Condition: Diabetes
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Total 188 results found since Jan 2013.
TNFAIP3 is anti-inflammatory in the retinal vasculature
CONCLUSIONS: TNFAIP3 serves as an anti-inflammatory factor in the retinal vasculature. Epac1 regulates TNFAIP3. TNFAIP3 may offer a new mechanism for regulating inflammation and permeability in the retinal vasculature.PMID:36034737 | PMC:PMC9352365
Source: Molecular Vision - August 29, 2022 Category: Molecular Biology Authors: Li Liu Youde Jiang Jena J Steinle Source Type: research
ABCG1 is Expressed in a LXR-Independent Manner in Patients with Type 2 Diabetes Mellitus
CONCLUSION: The study suggested that the expression of ATP-binding cassette G1 and high density lipoprotein-induced cholesterol efflux in macrophages were reduced in type 2 diabetes mellitus. Impairment of cholesterol efflux and ATP-binding cassette G1 gene expression in type 2 diabetes mellitus might be regulated by a Liver X receptor-independent pathway.PMID:36017862 | DOI:10.2174/1566524023666220822150820
Source: Molecular Medicine - August 26, 2022 Category: Molecular Biology Authors: Hui-Juan Wang Ji-Hong Wang Xin-Na Xu Xing-Shan Zhao Wei Liu Source Type: research
Tubular epithelial cell-derived extracellular vesicles induce macrophage glycolysis by stabilizing HIF-1 α in diabetic kidney disease
CONCLUSION: Our study suggested that albuminuria induced renal macrophage glycolysis through tubular epithelial cell-derived EVs by stabilizing HIF-1α, indicating that regulation of macrophage glycolysis may offer a new treatment strategy for DKD patients, especially those with macroalbuminuria.PMID:35962319 | DOI:10.1186/s10020-022-00525-1
Source: Molecular Medicine - August 12, 2022 Category: Molecular Biology Authors: Yijie Jia Jiaqi Chen Zhikang Zheng Yuan Tao Shuting Zhang Meina Zou Yanlin Yang Meng Xue Fang Hu Yang Li Qian Zhang Yaoming Xue Zongji Zheng Source Type: research
