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Effect of aqueous olanexidine versus alcohol-based chlorhexidine for surgical skin antisepsis on incidence of surgical site infections in gastrointestinal surgery: multicentre randomised controlled clinical trial (OEDO trial) protocol
Introduction Surgical site infections (SSIs) are among the most common nosocomial infections in surgery patients. Two types of preparations, povidone-iodine and chlorhexidine-alcohol, are commonly used in preoperative antiseptic procedures worldwide. However, there are inconsistencies among international guideline recommendations concerning skin antiseptics. This trial aimed to evaluate the superiority of olanexidine, which reduced SSI rates more than povidone-iodine in our previous randomised trial, over chlorhexidine-alcohol in clean-contaminated surgery. Methods and analysis This multicentre randomised controlled clini...
Source: BMJ Open - August 21, 2023 Category: General Medicine Authors: Takeuchi, M., Obara, H., Furube, T., Kawakubo, H., Kitago, M., Okabayashi, K., Aoyama, J., Amemiya, R., Fujisaki, H., Sano, J., Goto, R., Sato, Y., Kitagawa, Y. Tags: Open access, Surgery Source Type: research

Infants immunisations, their timing and the risk of allergic diseases (INITIAL): an observational prospective cohort study protocol
Introduction Vaccinations are considered to have a large impact on disease control, hence a multitude of vaccines in infancy is recommended. Retrospective studies suggest a possible relation between timing, kind or number of vaccines given in the first year of life and the subsequent incidence of allergic diseases. It must be clarified whether a causal relationship exists to ensure safety and reduce vaccine hesitancy. Methods and analysis Due to the high recommendation rate of vaccines, a long-term randomised controlled trial is not considered as ethically acceptable. Therefore, this study aims to observe prospectively th...
Source: BMJ Open - June 23, 2023 Category: General Medicine Authors: Wrenger, J., Martin, D. D., Jenetzky, E. Tags: Open access, Public health Source Type: research

Scabies cases misdiagnosed and treated as allergic diseases: itch as alarm
Acta Clin Croat. 2022 Aug;61(2):349-353. doi: 10.20471/acc.2022.61.02.22.ABSTRACTThe lack of scabies recognition by physicians is often caused by its similarity with other dermatoses and allergies such as eczema, urticaria, atopic dermatitis, allergic contact dermatitis, etc. The aim of this study was to present the most common misdiagnoses of scabies in physician's work. With the aim of preventing future misdiagnoses in physicians' work, we present 6 cases of patients (1 woman and 5 men, aged 23-82) who had been misdiagnosed prior to admission to our ward (tertiary care unit). In our patients, scabies was unrecognized for...
Source: Acta Clinica Croatica - February 23, 2023 Category: General Medicine Authors: Liborija Lugovi ć-Mihić Marija Dela š Aždajić Iva Be šlić Source Type: research

The need of an updated culture of "occupational" atopic hand dermatitis in children at the time of COVID-19
Acta Biomed. 2022 Dec 16;93(6):e2022324. doi: 10.23750/abm.v93i6.13135.ABSTRACTDuring the COVID-19 outbreak, handwashing emerged as an essential tool to prevent the spread of SARS-CoV-2 virus. It can put into practice using warm water and soap or, if not available, alcohol-based hand sanitizers (ABHS). Anyway, the use of warm water and soap is not always possible. On the contrary, ABHS are frequently used for their versatility, but can represent a risk factor for atopic dermatitis exacerbations in the pediatric age. At the same time, the Italian Ministry of Health established a school regulation, asking the students to per...
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Luca Pecoraro Giovanni Chiaffoni Giorgio Piacentini Angelo Pietrobelli Source Type: research

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